Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76557	Canertinib	GSE92742	MCF10A	Human	6h	0.4uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	TSC22D3; FOXO4; MECOM; NR2E1; MYBL2; LZTS1; CEBPA; TCF25; PBXIP1; FOXG1; LPIN2; BRF2; ID3; ID2; BRD8; HOXB7; MED24; HOXC4; TP53; TOX; TRIM22; LEF1; HTATIP2; HEY2; TAL1; HEY1; PIR; CARHSP1; CTR9; MEIS1; KLF2; ATF3; RBBP4; AEBP1; CALR; HOXC10; HOXC6; STAT3; HMGB3; KDM5D; PSIP1; TLE4; MEIS2; WT1; BRD4; MKL2; CITED1; RUNX1; TAF10; HOXA5; SPEN; RBPMS; NCOR2; TCF4; PSMD9
Down-regulation	69	MYC; ABL1; CHD1; PMS1; HHEX; CTBP2; HMGA2; WWTR1; CHD9; FOSL1; ZBED2; FOS; ING3; ETS2; FOXF1; TXNIP; RBPJ; NANOG; THAP11; RNF138; KLF10; BACH1; ENY2; NFE2L3; EHF; TFAP2C; ZNF12; JUNB; GCFC2; TGIF1; ZNF124; CREB3L2; ZFP36L2; IRF4; ELK3; HNRNPD; ZMIZ2; ZNF43; ZNF22; POU2AF1; NKX2-1; ERBB4; GTF3A; RYBP; AHR; KLF4; SOX11; USP22; HES1; EGR3; KLF9; ESR1; ZFP36L1; CEBPZ; ZNF239; SCAND1; NR4A2; ZHX2; SATB2; BCL11A; MYB; AR; HDAC9; SMAD3; NFKB2; ZNF331; PBX3; TRPS1; ZBTB20