Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76556	Canertinib	GSE92742	MCF10A	Human	6h	2uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	141	NFKBIB; TSC22D3; KMT2D; MEIS1; SMARCB1; RBM39; MSC; BRF2; TSC22D4; HDAC7; HDAC5; ZNF177; SIRT2; MEF2A; KLF9; MNAT1; PA2G4; ZNF556; BRD8; KDM4A; KDM5D; INSR; ST18; RUVBL1; TRAK1; PIR; MECOM; WHSC1; BRCA1; ERG; DBP; STAT6; SAFB2; YEATS4; ZBTB16; SAP30; PMF1; NR2E1; HOXC10; CBX5; PDLIM1; DMTF1; HOXD1; ESRRA; VDR; ASXL1; HDAC6; MEOX1; KAT8; PMS1; DPF2; BRDT; RB1; CEBPD; LDB1; HMG20A; PRPF6; KDM2A; TP53; MLXIPL; DDIT3; ID2; POLR2A; ZNF281; SNW1; CEBPA; VPS72; CCNH; MAZ; TAF10; BRD4; HOXD3; KDM5C; TULP3; MYCN; CALR; RNF141; HTATIP2; JUP; HOXC4; NFATC4; MYB; TTF2; CNOT3; ZFHX3; TRIM22; SPIB; EMX2; MED6; ARID1A; SMAD6; MAFG; SMAD2; ASH2L; GLI3; PAX5; ITGB3BP; PHF8; SPDEF; TOB1; COPS5; TWIST1; RBPMS; TOX; SSBP3; RARA; AEBP1; HOXA11; ATF5; SOX13; NFIC; NR1H3; PEG3; WT1; AATF; LITAF; HDAC1; MNT; PBX1; ZMIZ1; HMGB1; HOXA5; PLAGL1; SCAND1; NFIB; HSBP1; SMAD3; NCOR2; NR2F1; TAF1D; PRKDC; ASCL1; KLF7; KAT6B; FOXO1; CITED2; HOXC6; TRIM29; PSMD9; TCF4; LEF1
Down-regulation	133	MYC; JUN; ZNF551; ZNF136; ZNF215; FOSL1; IRF8; HDAC3; HIVEP1; NFE2L3; URI1; JAK2; CBX7; ELK4; KLF1; EGR2; ZNF652; PHIP; CDYL; HMGA2; CHD1; ZNF180; ZNF12; ZNF134; NR2F6; IRF6; REL; CTBP1; ZNF264; GATA6; ZFPM2; ATF3; KLF10; GRHL2; ID1; ZNF506; E2F6; ZBED2; CREBL2; NR4A3; RREB1; IRF1; SHOX2; NR4A1; ZZZ3; BCLAF1; PRRX1; TRIP6; THAP4; TBX21; MYT1; ZNF512B; ARNTL2; HOXB2; HOXB6; TDP2; UBP1; ZNF611; FOXE1; ZBTB38; CERS6; FOS; NFYA; BACH2; SP140L; BACH1; NR1D2; HOXB5; PRMT2; ZNF148; DEK; TAF7; TLE2; SSX1; ID4; ZNF32; ZNF586; TGIF1; CRY1; ELK3; SOX11; SLC2A4RG; CTBP2; EN1; ADRB2; ZMYND11; ZBTB20; TCF7; IL16; INSM1; CREG1; NFE2L2; NKX2-1; BBX; EGR3; ZNF160; ETS2; PHF1; MNDA; EZH2; KLF2; FOXK2; NFKB2; MYCBP; STAT4; FOXC1; POU2AF1; FOXG1; ETV5; MEOX2; ZNF274; NKX3-1; ZNF331; HES1; MLX; ECD; DAXX; SP3; ZFP36L2; STAT1; PTTG1; SOX9; KAT2B; CITED1; BASP1; BIRC2; ZNF239; MYBL1; TCEA2; BCL3; CEBPZ; NR4A2; DACH1