Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76514	Tgx-221	GSE92742	MCF10A	Human	6h	0.4uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	96	TBP; BRCA1; ZNF177; XBP1; SMARCD2; PITX1; ZEB2; MSX1; KLF12; HOXB7; PCGF2; TXNIP; AATF; TADA2A; HMGB3; PIAS3; ASH2L; KLF5; ZNF528; KDM5D; MAX; BCL6; ESR1; NR1H3; MED1; CREB3L1; UBE2L3; HOXC4; SMARCE1; HOXC6; BAZ1A; WDR77; EP400; ARRB1; KMT5A; RNF141; KAT8; PHF8; MAFB; GATAD2A; ORC2; RCOR1; SIX1; NCOA1; RUNX1; ZNF552; CEBPA; TRAK1; HOXB6; TAL1; HTATIP2; TRIM22; NR2F1; HOXC10; HDAC1; PAX5; PA2G4; PSMC3IP; ERG; ZNF516; DDIT3; ZNF83; PURA; PBRM1; ISL1; POU4F1; GABPA; ZNF131; SUB1; PRKDC; TAF10; LEF1; TBL1X; LOXL2; MLXIP; RUVBL2; ZNF432; TP53; MNT; MDM4; TRIM29; SIAH2; HSBP1; INSR; FOXO3; TAF1D; FOSL1; TLE4; ATF5; CBFB; POU2AF1; FOXC1; MYCBP; TCFL5; ZNF274; BCL3
Down-regulation	122	ZNF551; URI1; ZNF281; REPIN1; ZNF652; REL; CENPF; ZFP36L2; PHIP; ELK4; ADNP2; THAP11; INSM1; TWIST1; PNRC1; HMGB2; TAF1; SUPT5H; HMBOX1; TFDP2; ALX1; SFPQ; ZNF235; FOXK2; RFC1; NANOG; TFAP2A; RUNX3; VEZF1; ZNF532; RAD21; LMCD1; ZNF611; ZKSCAN1; BCLAF1; CREBL2; ATF7IP; BTF3; ZNF268; SCMH1; DEK; SOX10; NFE2L2; CRYM; RLF; RERE; ST18; HBP1; MEIS2; ZNF12; ELF5; COPS2; EGR4; ID4; CCNE1; HOXB2; ZNF112; NKX2-1; ZNF721; CREB3L2; RNF138; PIAS1; ZBED2; STAT4; KLF6; SMAD7; TCF7L1; ZNF264; CAMTA1; ZNF430; SMARCA1; TGFB1I1; IRF4; NR5A2; SMAD4; ZEB1; CUX2; SP3; ARID1A; APEX1; TGIF2; ARID5B; NFIB; DAXX; BNC2; MYRF; CITED2; SSX1; HHEX; HIPK1; ZNF512B; ERBB4; HEY1; NR4A1; ZNF423; MYCL; PHF20; ZNF160; TCF7; SOX11; GATA6; KAT2B; TRPS1; PBX3; NFKB2; ZBTB20; AFF1; MAF; FOXF2; ZIC1; EYA1; HOXA5; MYB; BCL11A; PEG3; SMAD3; IRF9; NR1H2; BIRC2; SCAND1; MYBL1; PBX1