Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76506	Pyrazolanthrone	GSE92742	MCF10A	Human	6h	0.4uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	ERG; XBP1; TOX; ETS2; RUVBL2; ORC2; KLF12; FOXJ3; E2F3; NFE2L1; ELK3; ZNF587; BMI1; HEY2; BRPF1; IRX5; TRAF6; GTF2I; ZNF175; POLR2A; RCOR3; JUND; RNF10; HOXA1; JARID2; MNT; NR3C2; AFF4; NAB1; DNMT3B; ADNP2; CRY1; CHD7; AEBP1; TFAM; MMS19; ZNF415; TEAD1; KDM5B; ETV1; PRKDC; ZSCAN18; SAP18; HNRNPD; SMAD2; KLF6; CAPN15; GABPA; TAL1; FOXN2; FOSB; PIAS2; PAWR; SMAD5; GATAD2A; MSX1; JUNB; MYCN; MAGED1; SMAD7; RFX7; PHF8; TSC22D2; SAP30; STAT6; NKX3-1; KLF9; YWHAB; HMGN3; TLE2; TAF1D; SMARCC2; CCNE1; HDAC1; HMGB3; TCF7L1; MAFB; CUX2; HTATIP2; PCGF2; RUNX1; CBFB; MAF; EGR2; ATF5; JUP; PBX1; TLE1; MED1; ZIC1; BASP1; ZMYM2; TRIB3
Down-regulation	94	EN2; HOXB2; PSMC3; FOXI1; CCNH; MYRF; FOXG1; HLF; JAK2; TP63; IRF5; COPS2; RBFOX2; REL; ARNT2; KAT2B; DEAF1; ZZZ3; ZFP36L1; PFDN5; ID3; IRF8; ZNF232; RXRG; PQBP1; MNDA; SRCAP; PITX1; MECP2; MXI1; SMARCD3; ENY2; ST18; HMGA2; NFE2L2; MED6; TOB1; ZNF266; FLNA; ZNF430; SPIB; ZNF611; KDM5D; VDR; ZNF721; MAX; NR4A3; PEX2; AHR; TGIF1; CERS6; NFE2L3; ZNF32; BACH2; THAP7; TOX3; ZHX2; ZXDC; NFE2; PHIP; E2F5; FOXA2; ETV5; GATA6; TEAD4; CBX4; BCL11A; SOX10; TCF21; IRF7; MEIS2; HIPK1; SALL1; TGFB1I1; LEF1; PHF20; TCF7; NFKB2; TRIM29; AR; ID1; HOXA5; TFAP2C; ZBTB38; HOXD1; ZNF331; MYBL1; SMAD6; EYA1; MTF2; ID4; ZBTB20; BIRC2; RELB