Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76488	Ruxolitinib	GSE92742	MCF10A	Human	6h	10uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	134	CEBPA; TRIM28; NFATC3; CHD9; MECOM; STAT5B; BHLHE40; PPARD; KDM4A; LPIN2; ZNF528; TBX2; HMGN3; XBP1; TBL1X; CTCF; ABL1; GTF2I; HMGA2; PRRX2; RBPJ; ING1; ZNF552; OSR2; CARM1; HLF; FOXL2; RREB1; EBF2; EDF1; POU3F2; MEOX1; CREB3L1; CHD1; ARID4A; RCOR1; NFKB2; ZBED1; TRIM25; HOXC10; FOXJ1; RNF4; MBD1; TADA3; TAF12; CHD3; DAXX; CNOT1; MSX1; TAF9B; SMARCD3; KDM2A; CTBP1; ZNF512B; ATF4; KLF4; ZNF467; RBBP4; ZMIZ2; ZMIZ1; RNF10; IRX5; PLAGL1; NKX2-2; TCEB2; BCL6; FOXC1; TDP2; BATF3; KDM5C; REST; SPDEF; REPIN1; CREM; PEG3; PDLIM1; CCDC59; DLX2; ID2; KLF2; LZTS1; IRF4; HOXD3; BRD2; CNOT2; RUNX3; GTF3A; CBX5; PFDN5; MXD4; SOX4; ZMYND8; MEIS1; MEIS2; BCL3; FOXF2; FOXG1; SOX9; DLX4; AES; CBFA2T3; IKZF1; ZNF226; ELF3; NR0B1; SMARCA1; HSBP1; TOB1; DBP; NEUROD1; BRD8; TSC22D1; KAT6B; FLNA; PHIP; ZNF331; NR2F1; HMGB3; MAF; PAX5; DLX5; DNAJC2; IRF7; ARID5B; LEF1; ZFP36L1; HOXC6; POU2AF1; TCF4; PIR; ZMYM2; MYCL; E2F2; SPEN
Down-regulation	118	ARID4B; NFE2L1; CCNH; EWSR1; THAP1; XRCC6; HOXB6; BRCA1; SUB1; RBM39; SETDB1; KLF13; TERF2; SP2; ZFP36L2; FOXO1; ACTL6A; CALR; THAP11; ADRB2; FOS; LYL1; ZNF532; MED17; ELK3; ZNF432; ZNF669; KLF11; BACH2; ADNP2; HDAC9; TSG101; SNAPC4; ANKRD1; ZBTB43; PRKDC; HBP1; PTRF; ILF2; FOSL1; CCNC; ERG; POLR3C; NPAT; ZNF350; SAP18; GATA6; PBXIP1; HHEX; TFEB; SAP30; TCF7L2; CREB5; RB1; BTG1; TCEA1; TCF21; PIAS4; SUPT7L; BBX; PPP1R13L; PSMC3; HOXB13; TFAM; AGO2; WWC1; TMF1; ID1; HTATIP2; IRX4; TBL1XR1; THRAP3; TP63; FOXN3; TCF7L1; JUNB; ETV1; YAP1; MXI1; TBP; TCFL5; ZNF85; ZBED2; FOXA2; IFI16; ZBTB16; ZEB2; EGR3; FOXO3; HOXA10; KLF7; SOX13; SMAD1; TFEC; RBPMS; PBX3; RUNX1; MTA1; MED13; RAD21; CREG1; KLF9; ATF5; ZHX2; CITED1; NLK; JUND; EMX2; FHL2; BNC2; BIRC2; SMAD3; NR1H2; MED1; ZEB1; MAFB; ZNF91; ZBTB20