Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76475	Pf-431396	GSE92742	MCF10A	Human	6h	0.08uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	TRIM22; NFATC3; KDM5A; VGLL4; ZNF14; OSR2; CERS4; TRIM28; TRIM24; ETV6; IRX5; TLX2; FOXL2; ZNF133; DLX5; BHLHE40; SOX12; HMGN3; HOXA3; ZNF136; CSDC2; MEF2D; SIX5; MAF; TGFB1; EVX1; TGFB1I1; USP16; ZNF671; GLI1; ZSCAN32; FLNA; E4F1; POU4F1; SP100; PRPF6; BTG1; ZSCAN31; ZNF571; ZNF112; MED15; GTF3A; ZNF292; ZNF12; ZNF304; TCF15; BRDT; CHD8; IRF7; VGLL1; WWTR1; ZNF415; ADNP; ZNF224; CTNNB1; TULP3; SPDEF; MDM2; TBX21; POLR2A; IRF3; PURA; HOXC10; TWIST1; TAF12; SKI; FOXJ3; CREB3L2; MECOM; DNMT3B; HLF; SOX4; TBX3; CNOT2; NKRF; FOSL2; NFKB2; PHIP; ZNF45; AHR; DLX4; EN1; IRF6; CBX6; PLAGL1; HLTF; ZNF443; GATA3; ZNF532; DAXX; ZNF43; SOHLH2; SALL1; ESRRG; ETV5; TCF4; FOXF1; RUNX3; NAB2; BBX; IKZF1; HDAC4; TFCP2; ZNF148; ZBTB38; TFDP2; HDAC1; SMARCD3; IRF9; KAT2B; CREM; ZNF124; NR2F1; MEOX2; ZNF93; SMAD6; MYCN; HIRA; SOX9; SOX11; TCFL5; CD3D; KAT6B; WT1; FOXF2; ZEB1; ZNF331; E2F2; TAF1D; CUX1; FOXC1; HOXA5; JUP; NR4A2; SMARCA1; TRPS1
Down-regulation	209	ZNF143; RAN; NFKBIA; TRIM33; NFYB; CCNA2; BMI1; HIPK2; THAP11; PMF1; HMGB2; FOSB; NFKBIB; HIVEP2; MEF2A; RSF1; BACH2; CDYL; BRIP1; BTAF1; SETDB1; MYRF; HDGF; TFAP2A; TRIM16; BPTF; HNRNPD; PSMC3; ACTL6A; ZNF354A; TCEA1; BCL10; UIMC1; CSDE1; RCOR3; NCOR1; TOB1; FOSL1; RCOR1; SUV39H1; EDF1; ZKSCAN1; VPS72; NPAS2; XRCC6; RORC; PHF2; PRDM10; UBE3A; COPS2; EHF; ZMYND11; ASH2L; INSM1; MED6; HDAC9; BASP1; SKIL; BAZ1A; WDR77; RBBP8; BCL11B; MAFF; NHLH2; MYNN; ATF6; PKNOX2; HMGA2; IFI16; MTDH; TBP; FOS; COPS5; ZNF770; HMGA1; NFYC; ZNF24; KLF4; PITX1; SERTAD2; CHD9; KLF3; TERF2; CHD7; RNF141; SMARCA4; SAP18; ESR1; TCF12; ETV1; AGO2; RYBP; CCNE1; SP2; TAF9B; TOX3; RNF111; JAK2; DEK; ZNF232; MED24; EGR3; IRF2; SIAH2; GATA6; ZHX2; ZNF652; SETD2; TSG101; RLF; VDR; BAZ1B; ETS2; MYT1L; NELFB; PAWR; VEZF1; WWC1; ZNF672; ADRB2; AEBP1; CRY1; EMX2; TFEB; PCGF2; CNBP; ZNF32; FOXN3; EZH2; TTF1; KMT2A; CDK8; E2F8; ID3; ASCL1; EHMT2; KLF11; TGIF1; ZNF140; HBP1; TAL1; TSC22D2; NLK; ANKRD1; STAT3; NCOA2; SNAI2; ZNF146; ZBED2; SMAD3; LMCD1; MKL2; RXRA; MYCBP; TLE1; HIPK1; SOX17; FOXO1; PSMD9; AATF; PRKDC; APEX1; GABPB1; MEIS2; TAF4; SPEN; FOXO3; ELF1; ID1; ETS1; CUX2; MED1; FOXA2; MTA1; PHF8; ZNF23; GTF2IRD1; JUND; MLX; ID4; SOX13; RBM14; HIPK3; SCAND1; CREBZF; RFX5; FOXA1; ZMYM2; RBPMS; THAP10; ERBB4; USP22; CCNC; OLIG2; YAP1; AFF1; NRIP1; PTTG1; NR1H2; TAF10; ATF5; PDLIM1; LITAF; MYB; TRIM29; CREB1; ERBB2; SMAD1; PBX3