Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76463	Ibrutinib	GSE92742	MCF10A	Human	6h	0.08uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	WT1; BRD7; ZNF329; RB1; TSC22D3; SUPT4H1; POU4F1; FLI1; ZHX2; DDIT3; ZNF468; TDP2; SKIL; ZNF268; FOXM1; TP53; ZNF415; HEY2; TCEB2; ZNF131; PAX5; KLF2; YEATS4; INSR; LOXL2; CREM; CUX1; HMGB3; YWHAB; ZNF217; GATAD2A; CITED1; LIN28A; ISL1; NFIC; ARID5B; KLF5; SOX11; ZNF226; BNC2; POU2AF1; GTF2IRD1; FOXO1; CITED2; ZBTB18; ZFP36L1; PEG3; TFAP2C; SMAD3; RBPMS; TRIM29; ZNF423; TCEA2; PSMD9; TRIB3
Down-regulation	88	BMI1; CDK2; HOXB6; BTAF1; PMS1; ZNF266; HOXB5; GATA2; TAF1D; MAFF; LIMD1; PPP1R13L; RBPJ; JUNB; SERTAD2; WWTR1; EGR3; KDM5D; ZBED2; ID3; ETS2; SOX9; RNF138; TCF12; TFEB; MEIS1; SMARCD1; IRF1; NAB1; ZNF24; PSMC3; SMAD4; SMAD7; HOXB2; NR4A1; IRF7; ELK3; NFIB; TLE1; NR1H3; VDR; HHEX; HDAC9; FOSB; ZNF532; TOB1; ST18; MXD4; KLF10; STAT1; HOXA5; AHR; SATB2; FOXD1; EHF; FOXC1; CALR; CREB3L2; PAX6; HMGA2; ETV5; CRY1; HES1; IRF9; ENO1; HOXA10; AFF1; MAFB; HEY1; ZBTB16; ZBTB20; BASP1; MTF2; MXI1; ID1; PIR; ZEB1; NRIP1; TXNIP; EYA1; FOS; MTA1; ZNF91; BHLHE41; SMARCA1; ZMYM2; NR4A2; DACH1