Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76461	Ibrutinib	GSE92742	MCF10A	Human	6h	2uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	154	GATA2; DMTF1; TSC22D3; DDIT3; KMT2D; HLX; POU4F1; TRIM22; ZNF205; MSC; ZNF415; MEN1; RB1; LZTR1; PEX14; MED12; MLXIPL; TRIM16; NR2F1; DPF2; CUX2; TRIP11; NFIL3; HOXB3; CENPB; HOXB6; POU3F2; SOX2; MEIS1; BTG1; RSF1; AEBP1; CIITA; RELA; HAND1; LEF1; EZH1; STAT6; ZEB2; MEF2A; DMRT1; MTDH; FOSB; ZNF580; ZNF444; UBE2I; GFI1; MBD2; HR; MNAT1; HOXC4; ISL1; NFATC4; SKI; PHF8; CTR9; TAF9; KDM2A; THRA; MSX1; FOXE1; GLI3; OSR2; CDIP1; CAPN15; ZNF175; HOXB2; SATB1; ASH2L; SOX13; ZFHX4; SMARCD3; THRAP3; NCOA2; PIR; MECOM; COPS5; ZIC1; PAX5; ZNF423; NR2C1; HEY1; CERS6; ZFPM2; RFXANK; SSBP3; BRD8; MDM2; MDM4; MAZ; POLR2A; SUB1; KAT5; MAX; ZSCAN18; RUNX1; NKX2-2; TWIST1; MEOX1; SHOX2; DBP; POU2AF1; GATA6; TRIM29; PRKDC; SNAI2; SPDEF; FOXA1; GATAD2A; ARID5B; HDAC1; TERF1; PBX3; SMAD6; TP53; MAFB; SUPT7L; KLF2; KLF5; NR0B1; TCF21; RFX7; RUVBL2; CBX5; CHD7; CBX6; MYCN; EGR2; ST18; HIRA; RBM14; MYRF; MAF; RAD21; INSR; TLE4; ERBB2; RFX5; TRPS1; TBX3; NR2F6; TAF10; PSIP1; BHLHE41; ZNF226; SPEN; ATF5; MEIS2; ZBTB18; PTTG1; TLE1; TCF4; PSMD9; TRIB3
Down-regulation	160	CDYL; TRIM27; YBX1; ZNF3; CHD1; TRIM32; PQBP1; ZNF184; ZNF573; ZNF551; FOXJ3; MAK; DEK; CSDE1; ABT1; BCL10; ZNF354A; NCOA4; CREBL2; VPS72; MYC; REL; THAP11; ING3; FOXL2; TTF1; BATF; SND1; NR4A1; TOB1; XBP1; ZNF667; MED17; ENO1; FOS; HMGA2; URI1; ZNF571; BRD3; ELK3; RNF138; RXRG; EDF1; XRCC6; AES; KDM5D; GTF3A; ZNF124; ABL1; ILF2; ZNF267; TAF1A; APEX1; WWTR1; SP140; ZNF165; E2F3; BIRC2; NFRKB; SATB2; ZBTB38; TSC22D1; BLM; NFE2L3; RBPJ; ZBED4; HOXA7; NR4A2; LMCD1; ZNF611; ZNF652; INSM1; ZNF721; CTBP2; TDP2; MKL2; LHX6; CREB5; CARHSP1; ZNF562; ZBTB43; AGO2; ZNF44; HSF2; SP3; TGIF1; MTF2; MED23; ERBB4; ZNF430; PSMC3; NR4A3; VGLL4; RORA; TADA3; SP110; HOXA5; LIMD1; ZNF468; MXI1; FLNA; EP300; UBE2B; ZNF711; ID1; MAFF; TEAD4; IRX5; ZNF324; IRX4; KLF6; MXD4; KLF4; STAT3; CDK8; ZNF264; ZNF107; HMGB2; ZNF32; ZNF426; NR1D2; ZNF12; MED13; PDLIM1; CDC5L; CCNE1; DAXX; HOXA10; CREM; ZNF160; FOSL1; RNF14; ZNF512B; KLF9; CAMTA1; ZFP36L2; ERG; ING2; PHIP; ZNF131; IFI16; ZNF22; BCL3; PLAGL1; ZNF239; BAZ1A; ZNF217; CRY1; SMAD1; SMAD3; ZNF331; TFAP2C; HIPK1; NFKB2; NPM1; ID4; SSBP2; DACH1; STAT1; RELB