Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76460	Ibrutinib	GSE92742	MCF10A	Human	6h	10uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	91	ID2; TSC22D3; CEBPA; SATB1; CTCF; TEAD3; NFIL3; SOX11; STAT5B; RBPJ; HABP4; ELF5; RNF10; BRD7; TCEB2; BTG1; ZBED1; NR3C2; PHIP; FOXJ3; NCOA6; TBL1X; IRX5; NFKB2; ZNF444; BCL6; CBX5; TDP2; ZMIZ1; DDIT3; SOX10; ARID1A; FOXM1; CDIP1; TCF25; MXD1; CREM; POU2AF1; KLF4; DAXX; NCOA2; WHSC1; RNF4; NR5A2; NR4A3; HBP1; MAF; ELF3; HEY2; IRF7; GCFC2; FOXD1; POU4F1; BRD8; REL; SPDEF; NCOA1; TRIM29; SP3; CITED2; FOXC1; ENO1; FOXF2; YEATS2; RUNX3; HIRA; KAT2B; MYBL1; HMGB3; FOSL2; LITAF; NR2F2; TCF7L1; PHF20; BASP1; AHR; ZNF423; SALL1; KAT6B; SPEN; NRIP1; CREG1; ATF3; MAFB; ID4; TCFL5; NR2F1; TCF4; TRPS1; MNDA; NR4A2
Down-regulation	94	MYC; CSDE1; HIF1A; HDAC9; SOX17; PRRX1; FOS; ZBED2; MAFF; ZNF136; ZNF266; ETV4; KAT2A; ING3; FOSL1; TFAM; ZNF91; MYRF; E2F3; PMS1; HOXB6; ETV1; TCF12; ORC2; WT1; CCNE1; CREB5; MED17; ZMYND11; MEOX1; ZNF443; KLF13; HHEX; HOXB5; SFPQ; MED1; EGR3; TFEB; MAX; PEG3; EMX2; JUNB; ERG; ARID4B; EHF; NCOA3; ASH2L; HES1; ETS2; TWIST1; CDK8; PRKDC; SNAI2; FOXO1; TAF1D; RUNX1; FOSB; MSX1; TGFB1; ZNF430; ZNF22; ZNF432; TOB1; LMCD1; ASCL1; PIAS2; RNF6; TRIP6; ESR1; HEY1; NPAS2; RYBP; ZNF93; MYCBP; RFX7; BIRC2; BAZ1A; PHF8; KLF9; MTF2; ZNF43; SSBP2; PAX5; MTA1; ZBTB38; EGR2; ATF5; PDLIM1; PBX3; ZMYM2; TBX3; BHLHE41; HOXA10; RFX5