Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76457	Linsitinib	GSE92742	MCF10A	Human	6h	10uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	55	TSC22D3; GATA3; CEBPD; FOXO4; BTG1; FUBP1; KDM5D; HOXC4; OSR2; TP63; LDB1; HBP1; KDM5B; HAND1; DDIT3; HMGB2; CCDC59; BCL6; ATF3; TBL1X; YEATS4; MBD2; HOXB7; TRIM29; TOB1; NR1H3; HOXA5; ELF5; BRD8; ZFP36L2; KLF6; HOXC6; PNRC1; FOXN2; TSC22D1; ID3; ISL1; ERBB2; ELF1; HDAC1; MEOX2; NR2F2; TXNIP; CREG1; SAP30; ARID5B; PDLIM1; HEY1; CITED2; DAXX; ERBB4; SOX9; PSMD9; TLE4; DACH1
Down-regulation	60	NANOG; TRIM32; TERF2; WT1; EGR3; ESR1; MGA; ETV5; HHEX; HMGA2; SATB2; LEF1; NFATC3; EGR4; ELK3; HOXD3; CREB3L1; ZKSCAN7; NFE2; WWC1; NKX2-2; FOSL1; MAGED1; LOXL2; ZEB2; FHL2; LIN28A; NR0B1; TEAD4; ZFP36L1; NFE2L3; HES1; EHF; ERG; SCAND1; TSC22D2; KLF10; INSR; SMARCA1; HOXB2; ATF5; IRF4; SMAD1; ZSCAN18; SMAD3; TCFL5; SALL1; THAP11; STAT1; HDAC9; ZBTB38; MYB; ZBTB18; ID1; ZMYM2; SSBP2; PBX1; MYBL1; MTA1; ZBTB20