Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76450	Mgcd-265	GSE92742	MCF10A	Human	6h	2uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	296	SOX2; SP140; MEF2C; PHOX2B; KDM5D; DMTF1; TRIM24; NFATC3; STAT5B; GATA3; ELF3; ELF5; ZSCAN32; HOXD3; TGIF1; BHLHE40; SSX1; CNOT3; FOXG1; OVOL2; TOX; ING1; EHMT1; XBP1; ZNF415; PPARD; ARNTL; ZBTB14; ZNF816; ZNF329; ZNF141; PRDM2; ETV6; TULP4; CIR1; SOX11; TFAP4; KDM5A; BCL10; PHOX2A; ZNF580; BATF; ATF4; TADA3; NR1D2; IRX5; NUP62; L3MBTL1; ZBTB44; TEAD3; ZFHX3; TDRD3; ZFPM2; MEIS1; NFAT5; PCGF3; SATB1; SOHLH2; RARG; TRIM22; IRF5; ZNF107; NHLH2; TCF4; ZNF532; MYCN; ING4; LZTS1; CEBPD; ELF4; ZNF117; TGFB1; RBPJ; ZNF175; NRBF2; IRF7; CHD1; ZNF444; SOX10; ZNF202; PROX1; ZNF623; SP100; TGFB1I1; HMGN3; MBD2; UBTF; ONECUT2; SSBP3; TOX3; BCL3; VGLL4; TRPS1; NR2F1; ZFHX4; JUNB; CEBPG; CREM; TRAK1; NR1H3; TDP2; ZNF124; HOXD1; MAF; ZEB2; FEV; NFKB2; ENY2; ZFP30; CBL; GTF3A; ZNF75D; WT1; SMAD2; CCNT1; SUPT5H; ZNF268; POU6F1; ZNF571; TSG101; ZKSCAN3; ZNF287; AGO2; EYA1; INSM1; MSC; ACTL6B; URI1; TBL1X; LIMD1; TCEB2; SOX5; HHEX; ZNF253; MED12; EBF2; EYA2; HAND1; MXD4; ID2; E4F1; EN1; USP21; NR3C2; ZNF257; ZNF562; SMAD6; HDAC7; HMGB2; RSF1; HMG20A; ZNF835; ZNF671; FOXF1; IKZF1; MECOM; CBX5; AHR; ZNF14; CAPN15; ZNF200; SPDEF; SMARCC2; BLM; ZNF701; TOPORS; TAF9B; NCOA6; PRDM1; ZZZ3; SMARCD1; NKX2-1; DR1; NCOA1; HOXC10; ARID1A; EP400; UBP1; ZNF682; BAZ2A; HESX1; ZNF211; ERBB4; DAXX; KDM5C; MEIS2; BCL6; LPIN2; TBX3; ZNF248; SSBP2; ABL1; ACTL6A; NCOA3; BRPF1; YEATS2; ZNF239; SP2; EGR2; ZNF419; E2F5; PDLIM1; SMARCA1; ZNF606; GATA6; ZNF3; KLF10; NFIL3; IRF4; TFDP2; WWP1; ZNF536; PIR; PHF20; NCOA2; RORA; ZNF587; JUP; RNF4; ASCL1; BTG1; EPAS1; FOXN3; ATF5; TEAD1; HMBOX1; DBP; NRIP1; ZNF93; ZNF264; SERTAD2; ZKSCAN7; ISL1; RBBP4; LMCD1; SATB2; IL16; NAB2; TRIM25; CREB3L2; ADNP; CBX4; POLR2A; TP53; ZSCAN9; MAZ; BHLHE41; NFE2L2; MDM4; ZNF131; MYCL; HES1; DNAJC2; TERF1; PLAGL1; GRHL2; STAT5A; ZNF331; ZSCAN16; PSPC1; CITED1; CREB1; ZNF267; TBL1XR1; NHLH1; CBFA2T2; ZBTB16; EHMT2; MYBL1; CAMTA1; TRIM29; MYB; HSF1; PRMT2; ZNF43; ZBTB38; MNT; SMAD7; FOS; NR1H2; CAMTA2; ETV5; E2F2; ST18; ZNF148; BBX; SCAND1; KAT6B; BASP1; ZNF226; MKL2; TFEC; FOSL2; NR4A2; ZBTB20; DACH1
Down-regulation	290	YBX3; PARP1; CCNA2; IKBKAP; CRK; NFKBIA; NCOA4; ZNF337; CTBP2; TSC22D3; ID3; EZH2; IFI16; TRIP6; TRIM16; ATF6; STAT6; EN2; THAP4; RREB1; REXO4; MSX1; CSDE1; CENPF; HOXB7; EWSR1; LHX1; HOXA7; RB1; ILF2; SMARCA4; FOSL1; GTF2F1; HDAC2; HOXB6; NOC2L; PPP1R13L; GMNN; SOX15; LOXL2; ARID4B; ZNF12; MED17; ATF2; SUZ12; PSMC3; CREB3; XRCC6; MDFI; ZNF83; KLF1; FOXI1; ZNF143; CRYM; HDAC6; PRRX1; TOB1; TFDP3; CDK8; KLF6; BCLAF1; FOXJ3; CHD9; SIM1; HNF1A; ZNF668; ZHX2; HOXB2; SMARCA2; MED16; PRPF6; CHAF1B; NKX3-2; ARL2BP; SNAPC4; NFKBIB; CCNC; EMX2; AEBP1; ADRB2; BTAF1; ASXL1; HOXA6; RBM39; YAP1; ZFP36L2; ZBTB40; ETV4; MYRF; COPS2; THAP11; HDAC3; LITAF; HOXB3; TBX10; NELFB; VEZF1; TTF2; TBP; ZNF516; ID1; MBD3; NPAT; ZNF394; WDR77; ZBTB18; MED23; SUPT3H; MYBL2; TCF25; HIPK1; NFIX; RCOR1; ZBTB11; LZTR1; ZNF263; ETV1; RCOR3; ZBED4; USP22; PNRC1; PHF2; PREB; SMAD3; ZMIZ1; DLX2; TEAD4; HOXB5; FOSB; MITF; SIN3B; GLI2; ZBTB7A; ASH2L; E2F8; JUN; MED1; PCGF2; HIF1A; ARNTL2; CNOT1; NCOR2; MED15; EHF; VAX2; JARID2; PAXBP1; MED6; FOXM1; SP140L; ADNP2; CCNE1; HDAC5; ELK3; MYC; ETS2; HIVEP2; PMF1; ZNF771; ZNF10; FOXO1; HOXA11; TLE1; KAT2A; TAL1; VDR; ZNF593; UIMC1; EDF1; CNOT6; CEBPA; ZNF232; INSR; USP16; CASZ1; ECD; KLF2; POU2F2; SUB1; NFYA; GATAD2A; RFX5; SMARCD2; ZNF410; RLF; DNMT1; GATA4; SOX9; AATF; TULP3; NFE2L1; HOXB13; ZNF721; PPRC1; CBFB; ZNF266; ZNF219; WWTR1; HDGF; HLX; ZNF672; PTRF; MMS19; ZKSCAN1; TCF7L2; ZBTB1; BAZ1B; MNX1; NKX3-1; PBXIP1; GMEB2; ZMYND11; IRX4; RUNX1; ZMYM2; BIRC2; ERCC2; KLF9; RHOA; RFC1; ERBB2; RFXANK; SPEN; TP63; TAF10; NR0B1; POU5F1B; CREBZF; PAX6; ZEB1; GABPA; LEF1; ZNF426; STAT3; TRRAP; TCEA2; MXI1; HSF2; ZNF32; ENO1; STAT1; OSR2; JAK2; KLF7; TCFL5; NR2C1; TTF1; HLTF; SOX13; TSC22D2; RNF14; KAT5; AFF1; CARHSP1; FOXA2; DEK; SOX17; CCDC59; TCERG1; IRF8; ARID5B; TXNIP; HOXA10; CHD7; PIAS1; BAZ1A; CRY1; NPAS2; BRD4; ZMYND8; TLE4; ZNF274; PBX3; RBM14; DDX5; ZNF423; SAP30; ESR1; CEBPZ; PSMD9; RING1; SNAI2; HIRA; ZFP36L1; OLIG2; NFE2L3; PTTG1; MNDA; PEG3; HOXC6