Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76434	Gsk-2126458	GSE92742	MCF10A	Human	6h	0.08uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	198	SOX2; TSC22D3; ELF3; ID2; NFATC3; HOXC11; FOXG1; ZBED1; SIAH2; BRCA2; OSR2; MEF2C; KDM5D; PITX2; CEBPD; TRIM22; CIZ1; SOX4; TBL1X; ATF4; ETV6; HOXD13; WNT4; SREBF2; ZSCAN32; ZNF562; ZNF492; TGFB1I1; PPARD; ZNF141; SATB1; CDX2; NR3C2; OVOL2; TBX6; TEAD3; FOXF1; ZFPM2; CBX6; ZKSCAN3; ZFP69B; ARL2BP; FOXE1; ZFP30; MAFB; ARNTL2; TCEB2; KLF4; NFKB2; CARM1; YBX1; TRIM24; ZBTB43; KMT5A; BCOR; ZNF329; TRAK1; ZNF257; ING2; ZNF148; MED12; ZNF835; CERS4; SCAI; CHD2; ETV4; KLF3; HABP4; INSR; HSBP1; ZBTB16; CIR1; ZNF33B; GFI1B; ETV5; HDAC1; NR1H4; RBL1; IRX4; NFE2L3; TERF1; ARID3A; CTNNB1; TERF2; TBX1; RORA; ZNF200; PHOX2B; ZNF682; DAXX; MEOX2; ZFY; TCF20; NFIX; ZNF331; ZZZ3; ZXDC; ZNF175; TP63; PLAGL1; ZNF253; MXD1; TOB1; IRF7; ZNF107; ZNF536; TFEB; ZNF415; BTG1; VDR; DLX4; ZNF623; TFAP2A; NR2F1; LHX2; ZNF268; CBX4; NKX2-2; DACH1; ZNF426; HOXC6; PBX3; ESR1; CREM; NFE2L2; ZNF606; FHL5; SOHLH2; TBX3; PLAG1; HMBOX1; CBX3; SOX5; ARNTL; HOXC10; CNBP; MEIS1; FOXF2; IRF9; REPIN1; TOX; HMGA2; SOX10; TCF12; REL; IRF8; RARG; INSM1; ZKSCAN1; MEIS2; PIR; NR0B1; SATB2; PEG3; RBBP7; KLF10; ZNF423; HES1; NRIP1; IRX5; DLX5; NR4A2; NPAS2; IRF6; SMAD6; ZNF91; ELF1; GTF2IRD1; OLIG2; MAF; JUNB; BHLHE41; WWTR1; FLNA; STAT3; NR2F2; ZNF131; MAGED1; HOXD1; AHR; THAP10; KLF6; BASP1; WWP1; ERBB2; ZMYND8; E2F2; ZFP36L1; TLE1; TRPS1; ZIC1; STAT1; ZMYM2; TRIM29; TCFL5; SMARCA1; KAT6B; SCAND1
Down-regulation	269	CEBPB; ZNF337; BMI1; ZNF473; MTDH; LOXL2; ZNF593; ARID4B; SAFB2; NFKBIB; FOSL1; MYC; ZNF576; CENPF; HDGF; CLOCK; POU2F1; PPRC1; BAZ1B; ATF2; SUV39H1; ZNF692; PMS1; THAP1; TBPL1; NRF1; RNF4; RUVBL2; GABPB1; SF1; BRF2; ZFHX2; EN2; RERE; RCOR3; CIC; HIF1A; NAB1; NFX1; PREB; ZNF135; ID3; DNAJC1; GMEB2; ADRB2; SP2; ZNF8; ABL1; ZNF24; HMGXB3; THAP11; PCGF1; NUP62; ELK4; CALR; MED23; MEF2A; WWC1; ASXL1; MED24; KDM5B; KAT2A; PAXBP1; BCLAF1; DPF2; EED; TCERG1; POLR3F; KAT5; ATF6; RRN3; ADNP2; LYL1; PSIP1; JARID2; ILF2; TRIM28; ZBTB7A; ASH2L; TBP; ZMYND11; DDX54; NOC2L; NKX3-2; HSF2; NFE2L1; ZNF10; TAF9B; MED17; PAX8; HLX; SMARCC1; SMARCA2; FOXJ3; CRK; BTAF1; ZNF783; ZNF45; TRAF6; HCFC1; CSDE1; RNF138; ERF; LMCD1; MYNN; PDLIM1; MZF1; TULP4; HLTF; ZNF432; FOS; ERCC3; BAZ2B; FOXA2; GLI2; BHLHE40; BPTF; ZNF672; EHF; TFAM; CCDC59; ZNF544; FUBP1; HDAC6; VGLL4; FOXO1; SFPQ; ZNF532; SAP30; ZFP36L2; PEX2; ZNF32; HBP1; TCEA2; RYBP; RELA; CRY1; SMAD1; ST18; YAP1; ATF5; MBD2; RB1; E2F6; CCNC; HIVEP2; ZNF764; KMT2B; LHX1; PHF2; MYRF; ETV1; HMGB3; ZNF222; SETD2; SREBF1; PPP1R13L; YAF2; SPDEF; SSX1; SIRT7; ERCC2; RBM14; SNW1; ELK3; FOXN3; ZNF232; ORC2; AIP; USF2; LHX6; VPS72; DR1; CBX7; MTF2; TBX19; ID1; UIMC1; SRCAP; HOXA4; ENO1; STAT6; HOXB2; TLE4; KDM2A; ZNF84; MED1; KLF9; ZNF227; SMARCE1; NFYC; PTRF; GLI3; AR; LITAF; ZBTB11; HIPK1; SMAD2; APEX1; MMS19; RFX5; DDX5; ZHX2; PHF1; ZNF146; VEZF1; CBFB; NEDD8; ELF4; BRD8; TMF1; PA2G4; HTATIP2; CCNE1; HOXA10; SAP18; SMAD7; HIPK3; MYCBP; SCMH1; MAZ; CDK8; SPEN; SUPT7L; SP140L; ATF1; EYA2; SLC2A4RG; SOX17; CHD8; PTTG1; AATF; TRIP6; IKZF5; STAT4; NCOR2; RBL2; CITED2; PAX5; TAF1D; HLF; SUB1; GABPA; CREB3L2; AEBP1; SOX9; DBP; NR1H2; ZNF83; SSBP2; SMAD5; ARID1A; CHD7; MLX; IRF4; CEBPZ; JUND; TCF7; CREB1; ZNF274; RUNX1; RBPMS; AFF1; POU2AF1; FOXO3; BCL3; ID4; MNDA; PBX1