Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76433	Gsk-2126458	GSE92742	MCF10A	Human	6h	0.4uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	108	TSC22D3; IKZF1; NR3C1; XBP1; RORA; E2F2; TBL1X; MED12; NFIL3; ZBTB16; HCFC2; ATF4; NFKBIA; TRIM22; FOXJ3; SIM2; FOXI1; RNF141; EZH1; HOXC4; UBE2B; RBBP8; HOXC10; PLAGL1; BPTF; CEBPG; HBP1; TAL1; ZNF189; KMT2A; ARNTL; DNAJC1; HOXC6; ZMIZ1; EBF2; ZNF165; BRD8; TSG101; PRRX2; IRF8; DEAF1; ZBED1; LPIN2; DDIT3; KLF9; TRIP6; TBX2; KLF7; CALCOCO1; ELF5; RB1; TGIF1; DLX2; MEIS2; ARNTL2; FOXD1; TXNIP; COPS5; TGFB1; TCF4; NRIP1; JAK2; TFDP2; HOXA5; KLF6; SP100; STAT4; NKX3-1; FOXN3; ABL1; TRIM29; KDM5D; URI1; FOXO3; AEBP1; POU4F1; EPAS1; TERF1; CBFA2T3; HIRA; POU2AF1; ELF1; FOXG1; STAT3; LITAF; PNRC1; NCOA2; PRDM2; STAT6; EZH2; FOXO1; NR1H3; IRF7; NFE2; CTR9; TCF7L1; TLE4; SOX9; NCOA1; RBPMS; TBL1XR1; MXI1; SAP30; IRF4; PAX6; CREG1; PSIP1; PSMD9
Down-regulation	136	PARP1; ZNF473; E2F6; MYC; TRIM27; ESR1; NANOG; FOXA2; TEAD1; ZNF551; NR4A1; SOX17; FOSL1; ZNF516; ZNF557; JUN; ANKRD1; TRIM32; MYEF2; HHEX; ZNF652; FOS; SRF; ADRB2; SALL2; WDR77; CDYL; ZNF444; RNF138; ETV4; THAP11; HES1; ZNF443; HOXB6; SOHLH2; E2F3; ZNF532; EGR4; ZNF266; PMS1; PGR; ZNF574; ZNF587; ZNF432; RBFOX2; NEUROD1; KAT2A; DLX5; WT1; ISL1; ZNF224; ZNF175; EGR3; PROX1; DDX17; ZBTB18; UBP1; OSR2; HDAC9; ETS2; ZSCAN9; NFATC3; FOSB; DEK; ZNF134; NFE2L3; SATB2; ZNF544; SSX1; ZNF12; SMARCD1; NKX2-1; HOXB5; CHD7; ZKSCAN7; MYCN; ZFP36L2; CBX6; MITF; HOXA11; ZNF267; PLAGL2; NFAT5; ZNF468; INSM1; LIN28A; HOXD1; ASCL1; TOX; TWIST1; LEF1; CUX2; SMAD5; MYCL; ETS1; PIR; HIC2; ATF3; ZNF264; EMX2; ZNF124; HOXB2; ZNF44; TFAP2C; MLX; EYA1; CALR; OLIG2; ZFP36L1; ZNF331; ETV5; TCFL5; FOSL2; CRY1; ZSCAN18; ARID5B; ID4; PURA; DACH1; KAT2B; BCL3; HEY1; SCAND1; MED13; TOX3; TLE1; STAT1; ZNF239; SPEN; ZEB1; PBX3; BIRC2; MYCBP; BASP1; NR4A2; ZIC1