Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76431	Gsk-2126458	GSE92742	MCF10A	Human	6h	10uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	358	PPARG; FOXO4; MEIS1; FOXG1; TBL1X; TGIF1; DMTF1; ID2; TSC22D3; MNAT1; ZFHX4; NFATC1; GATA1; HOXD3; VGLL1; XBP1; ZNF175; PROX1; KDM5C; WT1; FOXJ1; GATA6; RFX2; HLF; CEBPD; CHD2; ZFP64; ZNF329; ZIM2; LHX3; IRF4; ZNF266; CARM1; PPARD; KDM4A; ZNF286A; TOX; SOHLH2; IRF5; PRDM5; MYCN; MYOG; EHMT1; SMARCD2; SRY; MAF; HIC1; WNT4; GFI1; ZNF415; KDM5A; CREM; NKX2-2; ATF4; TRIM24; NCOA6; HOXB8; ZNF835; ZNF562; ZIC3; PLAGL1; APBB1; ZNF556; PRDM8; CSDC2; ZNF580; ZSCAN32; SOX5; LPIN2; BATF; ARID4A; MBD1; SIX1; STAT5B; PEG3; CENPB; HOXC11; MEN1; POU3F1; ZNF816; NANOG; HAND1; ZKSCAN3; SATB2; HLX; ZNF467; SMAD6; ATOH1; TEF; EPAS1; ZNF165; HNF1B; HABP4; RARG; ZNF671; NFATC3; PREB; ZNF141; FOXC1; BRD2; ZNF506; MED12; OVOL2; TCF4; SERTAD2; ZNF253; ASH2L; KMT2D; NKX3-2; PRDM2; HMGA1; LZTS1; ZNF443; ARNTL; KLF12; ZNF536; TEAD3; OSR2; PKNOX2; ZNF211; TRPS1; MYNN; NFYB; ZNF93; NFATC4; EYA1; NR3C1; NFKB2; ZNF324B; DLX5; EP400; ZEB2; HMGA2; KDM2A; PAWR; TCF15; STAT4; HES2; LHX1; PLAG1; MSC; TSC22D1; ZNF778; PIAS3; PRRX2; NFX1; KLF4; CAPN15; BRD4; MECOM; ZBTB3; BTG1; DACH1; FOXA2; SHOX; WWP1; CXXC1; NFAT5; HHEX; ZNF14; ONECUT2; ETV6; ZNF500; GCM1; FOXF1; ZFPM2; TCF7L1; WHSC1L1; FOXJ2; ZIC1; HMGN3; NCOA1; NPAS2; REPIN1; NFYC; CBX6; ING1; SOX17; IFNB1; TOB1; MXD1; NR1D2; HOXD10; TFDP2; ZNF510; SOX21; NFIL3; ZNF257; IL16; ZSCAN18; POLR2A; EVX1; PRDM14; TRIP11; ZXDC; HAND2; AEBP1; HOXD11; EBF2; DBP; DDIT3; HDAC11; BASP1; CBX2; ZMYND8; MNX1; RNF4; ELF3; TLE1; ELF4; SNAI1; ZNF75D; EMX1; RUNX1; NR2F1; ZNF423; PAX6; ERBB4; ZNF117; ZBTB25; MAGED1; HDGF; SOX2; EZH1; ELF5; NRIP1; MEOX2; SMARCA4; WIZ; IKZF1; JAK2; STAT5A; NRBF2; CERS4; ZNF701; SIAH2; FOXD1; CAMTA2; HOXC8; MXD4; CDYL; TOPORS; USP21; NR5A2; SOX11; EGR4; ZNF358; ZNF623; ETS2; TERF1; NR6A1; ZNF304; ZNF552; ZNF273; ZNF331; KLF9; RELA; MAX; KLF3; DAXX; ZNF131; ZNF571; PDLIM1; PRDM4; GABPB1; SLC2A4RG; NFKB1; PURA; KDM4C; SMARCA1; SRF; ADNP; BARX2; ZMIZ2; MYCL; ZBTB16; STAT3; RARA; ZNF217; NUP62; MLXIPL; CBFA2T3; PIR; SMAD2; ETV5; HOXA10; ZZZ3; NEUROD1; SSBP2; HIVEP2; BCL11A; ZNF468; PHOX2B; SSBP3; ZNF200; ZNF43; SOX9; MYT1L; ZNF134; PBXIP1; ZNF24; ERF; SPEN; NR3C2; HOXD1; NHLH1; CREB3L2; PHF1; PIAS2; ZSCAN9; CAMTA1; HEY2; NR4A3; MNDA; TAF4; IRF9; TXNIP; ZBED2; IRF6; HOXC10; IRF7; SOX10; ING2; CNOT3; SOX4; NCOA2; NR2F2; EHMT2; RBM14; NELFB; SCAND1; TLE4; E2F2; GTF3A; AHR; ST18; MTA1; JUND; ELF1; CBX4; NR1H2; PHF20; TCFL5; RING1; NFE2; SMARCD3; NLK; MYB; KLF5; FOSL2; ESR1; JUP; BHLHE41; TCF7; PBX1; RBPMS; PBX3; SALL1
Down-regulation	362	IFI16; MYC; HDAC2; ID3; CRK; CCNA2; JUN; XRCC6; SIX2; ZNF143; BRCA1; MED17; ATF2; VGLL4; MED23; RCOR3; NCOA4; CDK2; CSDE1; HOXB7; ZNF652; VDR; HOXB6; MED24; TAF5L; DRAP1; ARID4B; NCOR1; HDAC3; EWSR1; ARL2BP; TFAP2A; TFAM; ZNF337; UBE2L3; STAT6; TCEA1; ZNF593; MED15; ADRB2; NOC2L; NKX2-1; ASXL1; SP140L; NSD1; PSMC3; MSL3; KAT2A; PMF1; MMS19; SUMO1; LOXL2; TBP; BTAF1; PRKDC; SF1; TERF2; CTBP1; APEX1; ZBTB40; CNOT6; CBFB; BCLAF1; POLR3F; CCNC; BAZ1B; ZBED4; ZNF551; PAX8; NR2C1; TSG101; MED14; TAF7; IRX4; HLTF; WDR77; PSIP1; CEBPE; ZNF721; HSF2; FOXI1; PRPF6; SAFB2; ZNF263; RBM39; SMARCC1; BAZ1A; COPS2; TTF1; ZNF160; NONO; TCF3; SAP18; SETDB1; PAXBP1; ZNF668; ETV1; ZNF473; TRIP6; ZNF394; NFKBIB; CIZ1; YBX1; ZNF432; SSRP1; C1QBP; DEK; RFXAP; SP110; TRIM22; PGR; TAF11; ID1; TP63; CBX3; ZFHX2; MYT1; GTF2F1; RFC1; YEATS2; USP22; SUB1; THAP11; ZNF212; ZNF12; PNRC1; HDAC5; RRN3; LMO1; KAT8; ENO1; MSX1; MBD4; ZNF532; CHD9; SPI1; TFEB; SNAPC4; FOXJ3; PHF2; ETV4; ZNF232; NR4A1; KDM5D; SND1; ZNF32; ZNF292; MED25; MGA; ZNF215; PCGF2; ITGB3BP; HES1; ERCC3; MED6; FLNA; ASH1L; PRDM13; KLF7; ZNF611; PRRX1; ZNF8; MTDH; BACH2; ZNF135; MTF2; POU2F1; DDX17; RBBP5; RERE; ILF2; SMAD1; PRDM10; WWC1; REXO4; PPRC1; HIPK2; CTBP2; HBP1; TCF25; POU5F1B; VSX1; RBBP8; CHD8; LITAF; NFIB; MAML1; KAT7; TP53; SP1; SMAD3; TGS1; TOX3; UBE2B; GMEB2; CREB5; SUZ12; ZNF274; ZNF576; MITF; HOXB5; MECP2; MED21; SUV39H1; ATF1; ZNF410; MAZ; CEBPG; NR0B2; ATF5; ZNF544; TRIP4; USF2; ZNF136; HMGXB3; SNW1; FLI1; POU2AF1; HOXC13; BRD7; SIX6; ZNF692; ZBTB7A; THRA; HMGXB4; TRIM32; TCERG1; CNBP; INSR; MAK; ZBTB11; PIAS4; REL; MDFI; ZMYM2; HIRA; ZNF10; BRIP1; ZNF529; ZBTB1; SOX15; ZKSCAN1; NCOR2; ARID5B; CITED1; NFE2L1; HDAC1; IRF8; PAX9; FOS; USP16; RBFOX2; CNOT2; RNF14; BAZ2B; HDAC9; TFCP2; THAP4; E2F8; ZNF224; TWIST1; ZMYND11; PITX1; VEZF1; CASZ1; MLX; GTF2A1; PTRF; CDK8; WDHD1; EDF1; ABL1; IRF1; TCEB2; RHOA; CREBZF; POLR3C; TRAF6; SREBF1; TAF10; KAT5; RAD21; TTF2; ANKRD1; HIC2; VPS72; SFMBT1; GCFC2; DR1; DPF2; PTTG1; NKRF; RFX5; AES; CTNNB1; ZNF430; MNT; SMAD7; PATZ1; BIRC2; PLAGL2; CARHSP1; NFE2L3; ASCL1; BHLHE40; ZNF195; ERG; PSMC3IP; MYBL2; TLE2; MYBL1; MYBBP1A; KMT2B; CITED2; ZNF672; LEF1; SHOX2; FOSB; FHL2; NPM1; PSPC1; ZEB1; RBBP4; TBL1XR1; TCF7L2; KLF2; SMAD4; ZMIZ1; SOX3; PHF8; ZNF146; MED1; YWHAB; EGR3; KAT6B; YAP1; SUPT7L; AR; RNF6; ARID1A; EGR2; EHF; HMGB3; KLF11; CDC5L; STAT1; CDK9; PAX5; HTATIP2; ZNF239; CD3D; NKX3-1; FOXO3; DDX5; ERBB2; BNC2; CUX1; ATF3; ZBTB18; CEBPZ; CREB1; ZBTB20