Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76426	Gsk-1059615	GSE92742	MCF10A	Human	6h	2uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	93	IKZF1; TSC22D3; ZNF589; TRIM22; KDM5D; HCFC2; PBXIP1; DDIT3; ARNTL; RBL2; PEG3; KLF4; RBPMS; NFIL3; PNRC1; BMI1; WWTR1; ZNF117; HEY2; TOX; LPIN2; TP63; CERS4; TFEB; SP100; HDAC6; FOXO1; HMGB3; TLE4; NANOG; NR1H3; TGFB1I1; SOX13; TXNIP; CITED2; ERG; TAF10; KLF9; HOXB6; ZBTB16; ISL1; PBX1; ZSCAN31; NFIB; MDM2; MED23; GATA6; HBP1; MYRF; NR2F1; HOXA5; SUB1; MYCN; MAF; IRF2; BASP1; KLF2; TBX3; RUNX3; PTRF; NRIP1; SOX17; HMGB2; MED7; PHF8; FLNA; BRD8; TFEC; HLF; STAT6; ZFPM2; BBX; CD3D; ZNF91; CREG1; FOXF1; HHEX; EGR2; IRF7; MXI1; PAX5; IRF9; ID4; MEIS2; HEY1; LITAF; PIR; KAT6B; ZBTB18; PTTG1; MAFB; BHLHE41; MTA1
Down-regulation	125	NFE2L2; TRIM28; ZNF551; TRIM33; ZNF576; E2F6; ERF; MAML1; REL; CHD1; CIC; AGO2; ZNF574; ERCC3; PLAGL2; PCGF3; THAP11; E2F3; SHOX2; ZNF629; TSC22D1; SIX3; PIAS4; CLOCK; ELF3; TLE2; SFPQ; THAP4; PMS1; RCOR1; RNF4; MGA; NCOA6; VEZF1; PSMD9; ZBED4; ZNF180; ZNF227; SIX2; CTBP2; ARNT2; ID1; NEUROD1; NCOA4; HDGF; IRF6; HOXD3; ZNF652; URI1; ATOH1; PAX6; ZNF562; DEK; CDK8; SERTAD2; PRRX2; E2F8; SP3; BRIP1; ZNF45; GCFC2; SOHLH2; KMT2A; PREB; CAMTA1; NFE2L3; WHSC1; ST18; SATB2; FOXD1; HOXD1; E2F5; RNF6; SIAH2; ZNF443; HIVEP2; ZNF146; NKX2-2; AES; CREM; ZXDC; DLX5; FOSL1; TEAD4; ETS2; BAZ1A; HOXB7; HLTF; PHF20; THAP10; YAP1; CDC5L; HDAC4; HOXC10; ZNF331; MKL2; ARID5B; ZNF44; HMGA2; ABL1; NR4A1; ZMYM2; KLF10; MYBL1; PITX1; NR4A2; MED13; ZHX2; HDAC9; RUNX1; SATB1; ZNF239; NFKB2; ATF5; CEBPZ; TCFL5; TRIM29; DAXX; STAT1; MNDA; MTF2; BIRC2; CREB1; ZIC1; DACH1