Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76386	Afatinib	GSE92742	MCF10A	Human	6h	10uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	131	FOXO4; ZNF646; TOX; SIRT2; HMX1; TCF15; LDB1; HOXD13; HIF3A; DDIT3; PITX3; ZNF205; CDX2; HDAC7; TSC22D3; PFDN5; MYOG; ETV7; MLXIPL; PNRC1; MEF2D; ZNF500; SALL2; NFATC4; CCNH; SUPT3H; HOXD11; PRDM14; SIX5; TP73; ZNF91; SMARCB1; FOXG1; SPI1; NR2E1; KLF13; SPIB; SOX2; LOXL2; ELF4; TSC22D4; YEATS4; PCGF1; TEAD3; FOXJ3; ST18; ACTL6A; TTF2; ZIC3; BRD4; ZNF219; VGLL1; ZNF415; BTG1; TFAP2A; ZNF117; ZNF33B; ATF3; NAB2; BARX1; PEX2; SUMO1; MYCN; SIX6; PBX1; PROX1; SUPT4H1; VPS72; HBP1; ARID5A; MEIS2; NR2F1; SPDEF; IRF6; KDM5C; AIP; PAX5; NCOA1; ZFPM2; HDAC9; NR0B1; ZNF580; TCF7L1; CRYM; CNOT2; SSBP3; ZNF93; TULP3; SOX13; ASCL1; ZNF85; ZNF467; PBXIP1; EN1; MAZ; TCF21; ETS1; ATF5; CBFA2T3; SOHLH2; CALR; ZNF195; ID3; KLF7; TAF10; INSR; TCF7L2; TERF1; MKL2; CITED1; MED13; NFE2; CUX2; MYBL1; MYCL; TRPS1; NLK; AEBP1; ZBTB16; ZNF423; ERBB4; ZIC1; ZSCAN18; AR; CITED2; EMX2; IRF9; BASP1; KAT6B; DACH1; TRIB3
Down-regulation	153	MYC; TRIM28; CHD1; SMARCA4; NFX1; IKBKAP; FOSL1; SMARCC1; XBP1; TRIM32; ELK3; ETS2; TOPORS; YBX3; HMGA2; SFPQ; BCLAF1; EWSR1; TMF1; KDM5D; ELF3; UBP1; URI1; PARP1; SFMBT1; SOX11; BRD3; NUP62; ORC2; IRX5; DPF2; BMI1; GTF2I; TRRAP; ZBTB38; HIVEP1; EGR3; NCOA6; CREB5; MSX1; RCOR1; SETD2; WWC1; FLNA; MGA; TRIP6; CBX3; HNRNPD; ENO1; ZBTB1; LIMD1; EGR1; KAT7; ZBED4; ZNF652; FHL2; NELFB; SP2; PHOX2B; ADRB2; ARNTL2; AFF1; CHD7; FOS; ZMYND11; EDF1; CRK; NFKB1; ZBTB11; IRF1; ELF1; ZNF264; ZNF587; KDM5A; MED24; RBM14; JAK2; TFAM; TXNIP; HIPK3; REPIN1; TEAD1; SOX9; CTR9; RNF138; ISL1; PBRM1; NR1D2; SP3; REST; IKZF5; TSC22D1; PHF2; SIAH2; RBL2; NR2C1; GABPA; BIRC2; RUVBL2; KLF2; PURA; RNF14; PRKDC; KDM5B; SPEN; TP53; NFKB2; FOXO3; MYRF; ZNF146; PCGF2; BACH1; HOXB7; SATB1; FOXN3; TTF1; ZMYM2; BAZ1A; SATB2; MAGED1; JUNB; GTF2IRD1; PHF20; NKX3-1; STAT1; ZNF217; RUNX1; CBFB; YAP1; CEBPZ; HES1; ID1; ECD; ZNF131; CRY1; MLXIP; ZBTB18; HOXC6; NFE2L3; TCFL5; ZNF512B; SCAND1; RBPMS; TSC22D2; EGR2; HOXA10; MED1; MTA1; NR1H2; DAXX; MNDA; NR4A2; RELB