Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76384	Azd-5438	GSE92742	MCF10A	Human	6h	10uM	EID0439

Response Information :

Types	Number	Response transcription factors
Up-regulation	71	BHLHE40; POU3F2; FOSB; MAFF; SUB1; DRAP1; MYBL2; CSDE1; SAP18; MSC; HIPK2; NR2E1; BRD4; AEBP1; LOXL2; FOSL1; RB1; PKNOX2; NRIP1; HDAC6; DLX2; HMGA1; HEY1; HDAC1; TADA3; TGFB1; CNOT3; PFDN5; PEG3; SOX9; HOXB5; NR1I2; TP53; ZNF91; PQBP1; SMARCB1; CITED1; ZNF580; KLF4; TAF10; ASH2L; ZSCAN18; SPEN; TAL1; KLF10; PDLIM1; PAX5; KLF5; ZNF226; INSR; PRKDC; LEF1; PBX3; EGR3; NCOR2; FLNA; MEOX2; NR2F1; MAZ; PITX1; SNAI2; ASCL1; EGR2; PBX1; ZNF274; MYCBP; CREB1; TCFL5; PSMD9; BHLHE41; TRIB3
Down-regulation	181	CEBPB; ZNF184; CCNA2; CHD1; ADRB2; NFIL3; CDK7; TOPORS; ARID4B; CHD9; XBP1; ZNF292; NFYB; TRIM32; TRIM27; ZNF281; CENPF; TOB1; TAF1A; BRCA2; ZNF473; TGIF1; ARID4A; BRWD1; PHIP; TSC22D3; ZNF571; SIX3; RSF1; ZNF573; MAML1; ATF2; ZNF711; MGA; PMS1; ZSCAN31; REL; NPAT; ZZZ3; ATF7IP; PATZ1; ELF2; HIF1A; SAP30; VGLL4; HIVEP1; TSC22D1; MED23; ZNF200; ZNF263; SUV39H1; E2F6; ELF3; STAT4; MEF2A; CEBPA; ZNF7; HMGB2; RBPJ; ADNP; WDHD1; ZNF117; ZNF304; ZNF623; CDYL; BCL10; TLE1; ZNF12; TULP4; EN1; FOXJ3; RRN3; CRK; DEK; CNOT6; SOX4; ZNF107; DR1; GFI1; UBE2B; AHR; PCGF3; E2F3; HSF2; NFYA; ZNF3; ZKSCAN7; HBP1; AFF1; BLZF1; RORA; BRIP1; AGO2; KLF11; HMGXB4; RFC1; MED17; PHF20; KDM5B; ZFHX4; SFPQ; RNF111; ZNF165; SMAD4; ZNF124; VEZF1; MED20; KMT2A; PAWR; CARHSP1; FOXO3; TP63; MKL2; ZNF611; ZNF84; ZSCAN16; PRRX2; ZNF160; ZNF721; ZNF217; SP3; ZXDC; BRD3; E2F8; YEATS2; IRX5; MEIS2; FOXK2; NFE2L2; MYT1L; MED7; TBL1XR1; CD3D; NR2C1; ERF; NLK; ZNF146; MTF2; WWP1; EHF; BAZ2B; CTBP2; BACH1; ZFP36L2; ARID5B; ID4; NCOA2; DLX5; ZEB1; CEBPZ; TCF7L1; MYBL1; TXNIP; OSR2; NR4A2; HIPK1; CITED2; RUNX3; SATB1; GATA6; CCNE1; RAD21; WT1; TCF7L2; MXI1; ID1; TRIM29; PSIP1; DAXX; ZMYM2; SMAD3; BASP1; ZBTB20; KAT6B; NFKB2; ATF5; ZBTB16; STAT1; ZNF131; HOXA10; TRPS1