Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76365	Ruxolitinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	119	NFKB2; ZNF611; TBX3; ZNF623; TAF12; ZFP69B; SCAI; ZNF573; WWP1; SATB1; ZNF124; RSF1; HBP1; ZNF74; CSDC2; ZHX2; ERBB4; SOX13; TAF1A; MAML1; PCGF3; ZIC1; ZNF160; BRD4; SOX2; BHLHE41; HOXD1; ZNF12; CHD4; REL; PHIP; ZNF44; NONO; ZNF350; ZNF652; MYCL; PIAS1; SOX11; NANOG; FOXF2; MEIS2; ZNF117; ZNF529; ZNF331; RBPJ; BRCA2; BCL11A; CBX7; LIN28A; ATF2; CREB5; MED14; FUBP1; INSM1; ZNF665; CRYM; ZNF253; TBL1X; NR4A2; NFE2L2; DACH1; CAMTA1; PHF20; TRPS1; ZXDC; TRIM22; ZSCAN31; ZNF721; BRD2; KLF3; CREB1; RBBP5; ZFP36L1; RORA; POLR3C; HLF; E2F8; NR1H4; NR3C2; CTNNB1; ZNF551; SALL1; PRRX1; ZNF93; NCOA2; TCF7L2; TFAP2A; TBL1XR1; DEK; RAD21; SOX10; ID4; ZNF195; TOX3; ZBTB20; ARNT2; NKX2-2; ZNF22; FOXF1; LOXL2; HIRA; TDP2; ESR1; HOXB2; ZNF430; NFKB1; ZNF512B; PLAGL1; TRIM29; TOPORS; HDAC9; IRF1; STAT1; RREB1; MXI1; PEG3; NR1H2; WT1; MYBL1
Down-regulation	168	DRAP1; TCEA2; FOSL1; RUVBL2; ELK1; MTDH; NCOA6; HMG20B; HDAC6; TCERG1; ELF1; HR; DPF2; PTTG1; SETD2; PCBD1; TAF9; KAT5; ETV1; USF2; FOXD1; HSF2; PIAS2; ZHX3; SNAI1; MSX1; NCOR2; TRIP6; DNAJC1; ERCC2; VPS72; TSC22D1; ZFP36L2; TRAK1; SMARCD2; ZBTB18; YAF2; MED24; BMI1; TAF1D; HTATIP2; WHSC1; NFRKB; RHOA; TAF10; HIF1A; GATA2; NFIL3; SMAD5; PMF1; MTA1; TTF2; NAB1; KLF6; ASH2L; PLAG1; ZNF552; SAP30; BCL3; TEAD1; AIP; PITX1; NUP62; ZNF574; AFF4; HCFC2; CRY1; CDK8; KLF9; MED1; ZNF532; MEN1; MLXIPL; SKI; FOXO1; ING1; ZNF165; BLM; EGR1; HES1; HMGA1; ZNF222; NR1I2; SMAD1; BATF; NFE2; MITF; PHOX2B; MAZ; BAZ1A; PDLIM1; DDX5; RUNX1; TLE4; SOHLH2; SMARCB1; TFEC; RNF14; LHX6; MSC; FOXO3; SETD3; PCGF2; BATF3; RBM14; GATA4; RBPMS; MLXIP; PTRF; ERF; KLF5; MLLT10; ELF3; TRIM28; IRF6; ATF4; FOSB; STAT3; ZNF576; TSC22D2; HAND1; FHL2; RFX5; SNAI2; ZFP64; CEBPD; KLF7; BRCA1; SMAD2; HOXB7; HLX; LMCD1; JUNB; ARID4B; TWIST1; PIR; BASP1; HMGB3; UBP1; MYB; FOXL2; USP22; TOB1; MYCN; FOXN3; ID3; ZEB2; TP63; BHLHE40; FLNA; ETS2; CREG1; HMGA2; HOXB6; JARID2; ERBB2; KLF10; CEBPG; DLX2; NFATC3; SATB2; SSX1; SUV39H1; FOSL2; HOXC6; PPARG; MEIS1; RELB