Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76364	Ruxolitinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	38	SOX13; ZHX2; IRF9; ZIC1; HOXD1; NPAS2; PSMC3; SP140L; ENO1; BRIP1; ZNF22; ZNF24; HMGB1; SP110; CREB3L2; PQBP1; SPEN; PITX2; ERBB4; SALL1; WT1; TFAP2C; NKX2-1; SOX11; RYBP; ST18; ZBTB16; ZNF274; ZBED2; ZFP36L1; BCL11A; SUB1; MEIS2; GATA6; ZNF91; POU2AF1; ASCL1; PEG3
Down-regulation	73	HOXA5; HOXB7; MYCBP; CBFB; MSX1; EDF1; FOXO3; HEY1; ELK3; ZNF189; ING2; KLF5; BRD3; RUVBL2; ELF3; TGIF1; TRIB3; SMARCA5; TAF10; SAP30; HOXC6; RXRA; KLF4; CDK9; RUNX3; EGR2; TWIST1; PHOX2B; NR4A2; HMGB2; ZFP64; KLF6; MAZ; CIZ1; WWTR1; KLF10; LEF1; ZFHX4; TSC22D2; PIR; ZFP36L2; BCL3; ZBTB43; MECOM; SMAD1; FOXC1; ZBTB18; TP63; THAP11; AFF1; CTBP2; TCFL5; POU4F1; FOSL2; ZNF217; HOXB6; DLX5; YWHAB; CITED2; DNMT3B; PDLIM1; FLNA; TGFB1; BMI1; ZNF131; ID3; PBX3; STAT1; NR2F6; FOSB; NRIP1; PPARG; RELB