Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76361	Canertinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	99	TSC22D3; GATA3; ELF1; NCOR2; BRD4; FOXO4; MNT; EP300; MED15; ZMYM2; ARHGAP35; HBP1; WNT4; BTG1; PBXIP1; ZNF205; NR3C1; ID2; CEBPA; VDR; FOXO3; AR; ZNF768; MAF; TRIM29; CUX1; OSR2; PCGF2; SIRT7; ZNF268; MXI1; SIAH2; TFAP2C; MITF; ZBTB7A; PRKDC; ZNF226; ESR1; SCAND1; TMF1; BCL6; CUX2; ZFP36L2; CALCOCO1; ZMIZ1; TBX3; TCEB2; ZNF44; STAT3; ZNF195; FOXO1; AES; EYA2; FOXD1; IRF6; ELF3; FLNA; ZNF165; MECP2; JUP; PFDN5; TAF10; CHD9; SNAI2; SOX4; FHL2; TCF7L2; NR4A2; SP100; TRIM16; JUNB; KLF5; HDAC4; FOSB; TLE1; KLF9; CEBPD; KMT2A; DACH1; ZNF160; BCL3; CSDE1; MLXIP; ZKSCAN1; TRPS1; ATF3; EMX2; TCFL5; MAFB; NR1H2; LEF1; CREG1; CITED2; NRIP1; MEIS1; ATF5; WT1; AHR; CRK
Down-regulation	89	CENPF; FOXM1; PTTG1; CCNA2; PSIP1; HMGB2; BLM; GMNN; CHAF1B; MYBL2; EZH2; CCNC; CARHSP1; PAX6; RNF138; ECD; ETV1; NKX2-2; BRCA1; CBFB; HOXC11; RAD21; E2F1; WHSC1; DEK; PSMC3IP; MXD3; CDK2; SAP30; BCLAF1; BATF3; BRCA2; CDC5L; ING1; MTDH; CAMTA1; CCNE1; ETV4; ELK3; SFPQ; CEBPZ; RBL1; RBM14; ILF2; HLF; YBX2; HOXC10; E2F8; ING2; NFIB; TBL1XR1; ARID3B; SMARCA5; BRIP1; NR4A1; SP3; ITGB3BP; TAF5; CCNH; WWTR1; VGLL1; ZEB1; HNRNPD; ENY2; THAP10; NFE2L3; TFDP1; HHEX; MNDA; NR2F1; TRIP6; DNMT3B; ADNP2; CRY1; MYBL1; TOB1; HMGA2; ELF5; HMGN3; PDLIM1; SUV39H1; KLF10; ZBED2; ZBTB38; TCF4; PEG3; SSX1; ARID5B; PPARG