Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76360	Canertinib	GSE92742	MCF10A	Human	24h	2uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	208	IRF9; MEIS2; MED15; ZHX2; ID2; ZNF12; TBX3; ZNF611; DAXX; EP300; SOX2; TSC22D3; CSDC2; SSBP2; TRPS1; CD3D; KLF3; CALCOCO1; FOXK2; TAF1C; CDK2; JUN; HBP1; ZNF331; THRA; ZNF768; MZF1; TEAD3; PNRC1; SATB1; SUMO1; IRF6; TCF7L2; SP140L; HOXB13; OSR2; ZNF652; CBFA2T2; SHOX2; EZH1; ZNF124; RING1; ZNF91; RB1; TBX21; ZFHX3; CUX2; SUPT3H; ZNF117; ZNF160; AEBP1; CBX7; INSM1; CIR1; NFE2L2; ZNF688; RBL2; KLF9; ZNF467; YEATS2; EPAS1; UBE2B; MXI1; LZTR1; TCF25; ZNF573; LITAF; RBFOX2; DLX2; ZXDC; PBX2; CCNH; NCOA1; ZNF232; ZNF665; TFAP2A; FOXF2; ZNF350; ACTL6B; CDIP1; BNC2; SSBP3; BRD4; STAT2; BRD2; ERBB4; EHF; FOXO3; CREBL2; ZIC1; SPI1; NFATC4; ZNF354A; TERF2; HIC2; ZNF586; SMARCA1; BCL11A; ZNF43; ZNF266; ARNT2; ATF3; SNAI2; ZNF500; TAL1; SALL2; SPDEF; DACH1; THAP11; NHLH1; ZNF195; ZNF264; ZSCAN18; PHIP; PBXIP1; ZNF33B; REL; ID1; SP100; MYCL; MAF; HIPK1; LOXL2; WNT4; ZNF44; TGFB1I1; JUND; COPS2; DLX4; HMBOX1; MDM2; LYL1; TRIM29; HOXB2; POU2AF1; CHD9; SOHLH2; ID4; ZNF423; ZNF721; ZMIZ1; THAP4; KLF7; THAP7; ZMYM2; TWIST1; KLF13; ZNF93; CDK9; TCF7; JAK2; PHF1; PBX1; MNDA; SALL1; HOXC4; ZSCAN31; CSDE1; NFE2; ZFPM2; TGIF2; PRRX1; NR4A2; TOX3; ZNF512B; ZNF217; ELF4; MLXIP; DBP; HDAC9; TXNIP; TFAP2C; GRHL2; PFDN5; PEG3; ARID5B; CBFA2T3; ZBTB16; HHEX; INSR; SIM2; DLX5; JUP; ARID1A; ZFP36L1; ESR1; IFI16; MYBL1; JUNB; DDIT3; ZKSCAN1; ZNF131; FOXF1; WT1; CREG1; FOSL2; ZNF274; SPEN; GATA6; BHLHE41; LEF1; PAX5; MYRF; ISL1; PBX3; ETS2; TRIB3; BASP1
Down-regulation	187	PUF60; CENPF; IKBKAP; PSIP1; PSMD9; CCNA2; PTTG1; DRAP1; REST; HDAC2; EZH2; WHSC1; FOXM1; TCERG1; UBE2I; ARNTL; TBPL1; HMG20B; RUVBL1; FOSL1; MED27; HLTF; CTR9; RUVBL2; RHOA; REXO4; EDF1; TRIM28; HSF2; RBM14; ETV1; PMF1; NRBF2; MAGED1; SMARCA4; DNAJC2; SMARCA5; VGLL4; TRIM32; MSX1; ZBTB24; NUP62; WWTR1; MED1; BCLAF1; NR1I2; EGR3; SMARCE1; XBP1; RNF4; AATF; BAZ1B; ETV4; TBP; DDX5; EED; UIMC1; BRPF1; WDHD1; BRCA1; RBBP7; C1D; PHF2; CHAF1B; ING2; NELFB; ING1; ETV5; MED6; CBX3; NEDD8; ENO1; PARP1; GTF2A2; ZNF143; PPRC1; MEOX2; YEATS4; YAF2; PIAS2; ELK1; GABPB1; DPF2; NFIB; MTDH; BLM; MNAT1; TLE4; ECD; RNF138; BIRC2; PCBD1; IRX5; CBFB; TRIP6; POLR2A; SAP30; HMG20A; BATF3; MYCBP; PIAS3; DDX54; PLAGL1; EGR4; BMI1; RFC1; CCNC; FOXD1; ZBTB11; PLAGL2; TTF1; SMARCD2; ELK3; JARID2; ADNP; NR1H2; E2F8; THAP1; SFPQ; TMF1; SMAD2; HMGA2; HDAC1; EGR1; KLF5; HOXB7; CASZ1; SMARCC1; ORC2; ZFP64; CXXC1; CARM1; ZNF432; ZBTB1; UBP1; BRIP1; SMAD1; ASH2L; KDM2A; RBBP4; TFEC; ING3; RNF6; DR1; TSG101; HNRNPD; TCFL5; HLF; CLOCK; ZBTB18; SIX1; HAND1; SUV39H1; PHF20; HMGB2; TSC22D1; BAZ1A; SERTAD2; ZBTB32; YWHAB; RFX5; PCGF1; HTATIP2; TP53; FLNA; TBL1XR1; DNMT3B; RXRA; ELF5; ARNTL2; MYBL2; RBPMS; HMGB3; MTF2; APEX1; BHLHE40; USP22; IRF4; CITED2; MYB; SATB2; PPARG; SOX9; PIR; KDM5D; ZBTB38; SSX1