Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76359	Canertinib	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	220	NFKB2; IKZF1; ZNF586; AR; EP300; DAXX; ZNF124; ZNF611; ZNF264; PHIP; TEAD3; ZNF43; TSC22D3; ZNF117; OSR2; RARG; ZNF253; BNC2; ZNF768; MAML1; ZNF160; NR5A1; PRDM12; ZNF665; CSDC2; ZNF74; IRF6; CNOT6; ZNF711; HDAC3; TXNIP; NONO; EYA1; KLF3; ZNF671; ZNF506; ZNF44; INSM1; GTF2I; MYCL; ZNF140; MAF; PNRC1; KDM4A; STAT4; ZNF623; HMGN3; PRDM2; AES; NCOA1; CALCOCO1; ING4; PCGF3; HSF1; TBX3; ZXDC; STAT2; SRCAP; REL; TAF12; PHF20; POU2F1; SIAH2; ACTL6B; ATOH1; ZNF257; ADRB2; PRDM1; MEIS2; ZNF141; TBL1X; ZNF587; TERF2; RBL2; ZNF562; NR2C1; ZNF573; ZNF268; E2F2; THAP11; ZHX2; WT1; PAX6; ZNF75D; BTG1; HOXB2; ERBB4; ZNF304; TBX21; PIAS1; TRIM29; ZNF512B; ZMYM2; ZBED1; SP140L; SNAI2; WNT4; TRIM16; SSBP3; GTF2F1; ZNF551; ESR1; IRF7; TAF1; HOXB5; ZNF93; ZNF606; NR4A2; NHLH1; VDR; IRF5; ZNF273; RLF; FOSL2; CBFA2T2; NHLH2; HOXC13; ZNF652; FOXO3; ELF4; CBX4; ZNF701; UBE2B; DLX5; ZNF721; CTNNB1; JAK2; ZNF266; TRPS1; TCF25; ZNF84; MECP2; TCF7L2; ZFPM2; NCOA2; JUP; EYA2; HIC2; PRRX2; TERF1; NR4A3; ZNF358; ELF3; SREBF2; HIVEP1; ZNF415; ZNF195; ZSCAN31; ZNF3; ARNT2; YBX1; SPDEF; MNDA; NFAT5; BCL11A; URI1; KLF2; KLF13; RREB1; RORA; PQBP1; ID4; GATA6; DBP; ZNF331; MAFG; ZNF354A; ZNF33B; FOXA1; ZKSCAN1; TOX4; ARL2BP; PHF1; SP3; BACH2; ID1; E2F5; SCAND1; DACH1; SOX11; GRHL2; KLF5; TCEB2; HIRA; ING2; FOXF1; HDAC4; TDP2; ZBTB38; ZNF430; CBFA2T3; CREG1; CUX2; ATF5; TFDP2; MYCN; FOXF2; KLF11; ZNF423; TLE1; DLX2; ZNF217; MEIS1; LIN28A; SMAD6; NANOG; ZFP36L1; ZNF91; ZMIZ1; FOXG1; NKX3-1; ZIC1; TCF4; KLF4; HMGB3; SATB2; TCF7; EHF; TOX3; PEG3
Down-regulation	199	CENPF; PSIP1; FOSL1; YEATS4; PTTG1; CCNA2; CBFB; ETV1; WHSC1; MED1; BLM; CTR9; EZH2; TBPL1; TCERG1; NUP62; RUVBL2; EED; TTF2; DDX5; TBP; C1QBP; RUVBL1; DRAP1; IKBKAP; PMS1; CAPN15; UBE2I; CCNC; C1D; BRPF1; HSF2; FOXM1; HDAC6; ECD; BRCA1; MBD2; RBM14; RHOA; CCDC59; POU3F2; POLR3F; MTF2; MED21; DNAJC2; RFX7; PPRC1; REST; CITED1; YAF2; SMARCA4; MED27; ZNF692; MTDH; ORC2; HDAC9; JARID2; PCBD1; REXO4; TAF10; MED13; KMT2B; PMF1; ZNF143; GABPB1; MLXIPL; HIF1A; ZNF302; EGR2; ELK1; RNF4; MSX1; BRIP1; NFKBIB; MYBL2; NRBF2; TRAK1; PHF2; BIRC2; ID3; NFIB; TTF1; CRY1; TSC22D4; WDHD1; HCFC2; TAF1D; ELF5; TRIP6; NR1I2; SAP30; EGR1; ZNF23; SETD2; PIAS2; ETV4; MED4; PHF8; TFCP2; NFIL3; IL16; NEDD8; BRD8; ABL1; DMRT1; ERG; STAT6; TAF5; POLR2A; AIP; BPTF; MED24; HDAC1; MNAT1; ZNF432; SMAD2; ZNF267; ANKRD1; HLTF; PCGF1; BATF3; SIX1; BCLAF1; TADA3; DDX17; NR2F1; ELK3; NELFB; CLOCK; CALR; DR1; ING3; PA2G4; TFAM; CEBPZ; NRIP1; TOPORS; HMGB2; ZBTB32; BAZ1A; KLF6; WWTR1; SREBF1; CREB5; RERE; DNMT1; MAFF; XRCC6; SMAD1; FOS; BRF2; ETV5; ASH2L; NCOA3; BMI1; ZNF226; ZNF473; BHLHE40; HDGF; TRIM28; NKX2-2; ENO1; TWIST1; KLF7; ZNF165; SAP18; TCFL5; ARID1A; HOXB7; SMARCA2; SSRP1; ITGB3BP; NR2F6; FOXA2; ZEB1; RNF138; HMGA2; RBPMS; RFX5; MYCBP; CBX6; NR2F2; MAZ; SUB1; ZNF593; CSDE1; TBL1XR1; ZBTB18; MECOM; HTATIP2; SUV39H1; PAX5; SERTAD2; HHEX; ZNF281; SOX9; PPARG; ASCL1; KDM5D