Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76331	Vx-745	GSE92742	MCF10A	Human	24h	0.08uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	169	SATB1; NFKB2; TEAD3; MTA1; CEBPZ; AR; PSPC1; ZNF239; ZNF12; TGIF1; ZBTB44; JUP; PRDM2; ZNF611; ZNF571; SUMO1; ZNF74; SUPT3H; CDC5L; DAXX; ZNF354A; RCOR3; NR1H3; ZNF281; CBX7; BRD4; REL; KLF13; PIAS1; ZNF467; TLE2; ZNF195; TBX3; MAFG; ZNF44; TCF4; SMARCA1; POLR3C; IRF9; POU2AF1; ZNF711; ZNF117; LHX6; DLX2; KLF7; IRF7; TCF3; ZNF544; PROX1; PSMC3; PCGF3; KLF11; LOXL2; POU2F1; DEK; ZNF562; ZNF350; HOXC4; SIN3B; ZNF124; ZFPM2; NFATC4; PAWR; ZNF131; SP140L; HMGB1; CREB5; BCL6; ARNT2; CREB3L2; SLC2A4RG; PBX2; AES; CCNH; ZNF43; OVOL2; ZNF232; WT1; TCF7L2; FOXA1; NKX2-2; SPDEF; HBP1; SRCAP; IRF6; HOXC13; ZNF423; ZNF22; HIRA; CUX2; LIN28A; KLF3; GTF3A; RBFOX2; MYBL1; ZHX2; ZNF331; ZMYM2; NR5A2; NR1H4; ZNF654; TRPS1; SOHLH2; RBBP8; RBPJ; ZNF3; SFMBT1; YAP1; PAX5; ZNF93; CNBP; NANOG; SMAD1; ZBTB20; CBX4; HIC2; MNDA; HDGF; BACH2; ATF5; ILF2; TDP2; NFATC1; THAP7; SMARCE1; TBL1XR1; ZNF512B; CREB1; NKX2-1; IRF1; MYCL; CNOT3; HOXC10; EN1; ZFP36L2; HOXD1; CUX1; HMGB2; USP16; CLOCK; CEBPD; RYBP; ZIC1; NR2F6; TFDP2; LMCD1; HOXC6; TCEA1; SP110; TCF7; ZFP36L1; NR4A2; ERBB4; ZNF430; ZSCAN18; SPEN; SIM2; HOXB2; ATF3; BCL11A; ID1; RORA; NFIB; LEF1; NR1H2; MEIS2; CREG1; NKX3-1; ARID5B
Down-regulation	176	TCERG1; MED1; HSF2; HDAC6; ATF6; EED; PIR; CTR9; SETD2; JUN; RFX7; SMARCA2; RHOA; TTF2; ASH2L; NCOA6; KAT7; BLM; TCF12; AATF; WHSC1; IKBKAP; TRIP6; MED24; MSX1; GATA3; REST; PHF8; ZNF528; TAF10; GTF2A1; TRAK1; TMF1; ELF1; HDAC1; BAZ1A; MAFF; TRIM24; ETS1; SAP30; SOX15; TAF4; NEDD8; YEATS4; PCBD1; ID2; BRF2; POU3F2; HIF1A; NRBF2; HDAC9; ETV1; PCGF2; KLF12; CREB3L1; PLAG1; RBM14; MITF; PSMC3IP; HES1; PTTG1; RBL1; ADNP; MED6; NCOR2; RUVBL2; RNF111; SMARCD2; PURA; TXNIP; HNRNPD; ZMIZ2; SIX1; NFKBIA; HEY1; MAGED1; ZNF292; BAZ1B; ARRB1; ZEB2; SMAD5; BAZ2B; ZMYND11; ING3; ZBTB11; MTDH; PRKDC; BATF; TP53; ZFP64; NCOA4; NUP62; KDM2A; BTG1; BMI1; ZNF552; TEAD1; UBE2B; EP400; FOSB; SOX17; CITED1; BCL10; RBBP7; TSC22D2; RRN3; ING2; MSC; STAT5A; ZNF516; AFF1; NCOA2; SHOX2; KLF4; TOB1; ATF7IP; SUB1; EMX2; LPIN2; MKL2; EDF1; EGR3; LZTS1; RBPMS; NR2F2; TCEB2; BBX; NFE2L1; JUND; ASCL1; SMAD2; HIPK3; VDR; EGR2; BCLAF1; RXRA; KDM5B; NRIP1; THAP11; TP63; UBP1; REPIN1; ZBTB18; ZBTB38; BATF3; HTATIP2; NR1D2; ZNF468; RNF6; USP22; TRIM22; NFE2L3; KAT6A; RUNX1; TCFL5; PITX1; FOXN3; MYCN; SATB2; AHR; EYA2; YWHAB; FOXC1; TRIM16; IRF4; PBX1; MECOM; HOXB6; BASP1; CITED2; TLE1; EHF; KDM5D; PPARG; PEG3; SUV39H1