Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76330	Vx-745	GSE92742	MCF10A	Human	24h	0.4uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	214	SATB1; NFKB2; GATA2; TBX3; CBX7; TCF7L2; PRDM2; DAXX; ZNF586; ZNF571; MGA; ZNF562; TEAD3; PAWR; TAF1C; ZNF331; MYT1; EP300; ZNF623; SLC2A4RG; ZNF136; ZNF32; PHIP; NPM1; ZMIZ1; CEBPZ; ZNF124; ZBTB44; TCF4; NR2C1; NCOA4; ZNF264; ZNF175; ZNF239; PSPC1; KLF11; ZSCAN31; NR3C2; MXI1; TGFB1I1; ELF2; ZNF266; WWTR1; SOX2; TAF12; TRPS1; CNOT2; ZNF140; GATA6; FOXJ2; ZNF44; LIN28A; ZNF551; ZNF611; AR; KAT2B; ZNF443; SCAI; ADNP2; ZNF350; MNDA; ZNF544; ZNF131; TFAP2C; THAP7; SUMO1; HLF; CERS4; CSDC2; KDM4C; PAX6; KAT6B; FOXF1; ZNF512B; ZNF304; NFIB; PHF1; BRCA2; CCNE1; ZNF14; TLE2; ZNF573; SCAND1; HDAC3; FOXF2; ZNF268; ZBTB20; ZNF12; IKZF1; PHF20; ZSCAN32; ZNF3; BTG1; PRRX1; PQBP1; GRHL2; ZNF45; ZNF180; WWP1; ZNF529; ZNF177; ZNF652; ZNF10; ZNF500; KLF13; NANOG; CREB3L2; SP140L; ID1; AGO2; CD3D; ZNF273; JUNB; TRIM29; NKX2-1; ZFX; ZNF329; ATF2; E2F2; BACH1; ZIC1; ZFP36L2; CCNH; IRF9; NKX2-2; ARNTL2; RORA; ZNF232; ZNF117; SOX3; IRF6; CEBPA; HDAC4; LITAF; PCGF3; KLF3; CUX2; NR1H2; SIM2; TFCP2L1; HMGB1; ZEB1; COPS2; TFDP2; SALL1; CDK2; ZNF43; IRF5; SRCAP; E2F8; CNBP; BTF3; ZNF426; CENPB; ERBB4; NR4A3; NR4A2; DDX5; ZNF354A; ZFHX4; HIC2; DNMT3B; TAF11; INSR; BHLHE41; TOB1; HIVEP1; SP3; RXRA; ZNF85; KLF4; ZBTB39; NR2F1; TCF7; PLAGL1; ARNT2; NFATC3; TXNIP; TCEA1; ZNF93; NFE2L3; SOX11; RREB1; ZNF160; CERS6; MECOM; MYB; ISL1; PURA; OSR2; MEIS1; NRIP1; MYCL; GCFC2; PBX1; ZNF430; SATB2; CREG1; HHEX; HEY1; TP63; ZFPM2; OLIG2; GTF3A; ZSCAN18; CALR; DLX5; MAFB; POU2AF1; SMAD6; ZBTB16; JUP; FOXG1; EHF
Down-regulation	224	UBE2I; FOSL1; MED1; RHOA; MED24; PMF1; TSC22D3; TAF10; RFX7; SMARCA4; BAZ1A; HDAC6; HIVEP2; AATF; CENPF; TRIP6; SMAD3; TCERG1; NEDD8; SMARCD2; ZNF384; AFF3; PARP1; IKBKAP; BRD4; EGR3; SOX17; ZNF528; NFKBIA; EDF1; MSX1; ETS1; CBX3; VPS72; GTF2IRD1; JUN; ETV1; PUF60; RNF6; GTF2I; RUVBL2; SETD2; ZMIZ2; CAPN15; SND1; ASH2L; HIPK2; CTR9; MLXIPL; MTA2; YEATS2; TRRAP; IRF8; RLF; HDAC9; HCFC1; SMAD5; RBM14; ELF1; DMRT1; FOXD1; PCBD1; VDR; PHF8; HDGF; HOXB7; RUVBL1; HSF2; UIMC1; MAGED1; SAP18; TRAK1; PPRC1; EGR1; PSMD9; ZBTB18; DNAJC2; NUP62; WIZ; BACH2; KDM2A; STAT3; BRD7; NFKBIB; FOXO4; REST; SMARCE1; CBFB; LEF1; SSRP1; ZNF672; PAX3; ID2; HDAC1; FOXO3; PHF2; MMS19; MTDH; MED4; RBL2; RFXANK; HOXB6; USP22; MED23; ZIM2; CHD3; IFI16; CAMTA2; TRIM28; USP21; FLI1; SMARCB1; DEAF1; BAZ1B; RFX5; SMARCA5; WDR77; CHD4; RNF141; HNRNPD; ALX1; KLF12; NCOA6; TAF6; CRYM; HIF1A; POLR2A; THRAP3; RERE; ELF3; ZNF432; MYC; CHD7; BIRC2; TSC22D1; SOX13; DPF2; IFNB1; TRIM22; ENO1; MLX; TAF1D; CNOT6; SPEN; SAP30; FOSB; SF1; SUZ12; IL16; TMF1; EN2; TBP; KMT2B; HLTF; BAZ2A; RELA; ZNF516; TFE3; MAFF; RBPJ; BCL6; BATF; CITED1; ZNF83; ATF7IP; SMARCC1; ZNF580; MLLT10; ATF1; MTF2; TCEB2; CUX1; BASP1; PTTG1; TSC22D2; ENY2; KDM5B; NR2F2; PDLIM1; LZTS1; TBL1X; TFAM; MYRF; ID3; FOXA2; ELF4; MDM2; NCOA3; HLX; TGIF2; BCLAF1; RBBP7; GATAD2A; KLF6; ZFP36L1; MYBL2; TFDP1; EGR4; HOXB2; TWIST1; HIPK3; TP53; HOXD3; ERBB2; JARID2; VGLL4; SSX1; MKL2; KAT6A; DACH1; MEIS2; SOX9; NFKB1; EMX2; BMI1; STAT1; ATF5; ABL1; FOSL2; KDM5D; PEG3; CRK; SUV39H1; RELB