Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76329	Vx-745	GSE92742	MCF10A	Human	24h	2uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	105	SMARCA1; TEAD3; TBL1X; AR; ZNF136; TBX3; ZNF544; FOXA1; CENPF; RSF1; SUMO1; GATA3; PURA; KMT2D; NPAS2; CNOT6; WT1; BNC2; RUNX3; HOXB2; CREM; ZNF562; MEF2C; ELF3; ZNF552; ZNF329; RELA; MEIS2; SOX10; ZNF165; TRIP11; PKNOX2; ZNF350; SP100; ZNF331; MED23; NCOA1; CREB3L2; SPDEF; ATF3; SKI; EYA1; HMBOX1; TRIM22; CD3D; BANP; HIC2; ESR1; TCF12; HOXA1; TRPS1; SOX17; ZNF410; RBPMS; EMX2; CBX5; CREB3L1; CUX1; MNAT1; ZNF415; TAF7; CLOCK; ZNF264; SIM2; PEG3; MYCL; TRIM24; PRKDC; SSRP1; RBBP7; EYA2; CREB1; HMGB3; NR2F1; AEBP1; CCNH; BTG1; CEBPD; HMGN3; AHR; ERG; KLF2; CRYM; TOPORS; PIR; SERTAD2; ZSCAN18; CBX6; NKX3-1; IFI16; TFAP2A; BHLHE40; PLAGL1; KLF6; NR2F6; SMARCD3; FOS; ELF5; YWHAB; TCF4; BCL11B; LEF1; KDM5D; MYRF; MEIS1
Down-regulation	105	CEBPB; ATF1; HHEX; PPRC1; CENPB; CDK9; ID1; IRF3; KLF9; DEAF1; CREB5; SREBF1; LOXL2; CREBL2; SHOX2; MTA1; ZBTB20; BLM; MLX; CREG1; PROX1; ZNF672; TGFB1; PSMC3IP; KLF1; PSMC3; CAMTA1; TAF10; ZFP36L2; RNF138; NFIB; JUNB; ERF; ZIC1; EGR1; TEAD4; CBFB; NFE2L1; CBX4; BATF3; DBP; ID3; TRIP6; ELK3; GTF3A; SPI1; THAP10; PTRF; IL16; HAND1; TWIST1; ARNTL2; APEX1; CITED2; KLF4; JUP; ZNF423; HOXC10; PPARGC1A; NKX2-1; FOXA2; JARID2; TLE2; DLX2; INSM1; LHX2; CNOT3; VEZF1; GATA6; IRF8; HLF; STAT6; PBX3; ATF5; ELF4; BCL3; FOXF1; IRX5; STAT1; BMI1; KLF5; SAP30; CIZ1; NRIP1; MNDA; HOXA10; SOX11; NANOG; MAFB; FOXN3; IRF1; ZNF593; THAP11; MECOM; VGLL4; USP22; PDLIM1; AFF1; CTBP2; PBX1; ZNF131; NR1H2; SOX9; ETS2; BASP1