Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76298	Pelitinib	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	166	EED; E2F2; TSC22D3; IRF9; CALCOCO1; ZNF611; ZNF652; AR; TBX3; ATF3; EZH1; WNT4; TEAD3; CBX7; AES; DAXX; ESR1; PRDM2; KAT2B; PBXIP1; SETDB1; BARX1; ING4; NFATC4; CDIP1; ZNF688; MXI1; ARHGAP35; SMAD3; RARG; ZNF768; ZNF264; MED15; ZNF587; TULP3; ZNF160; THRA; PBX1; TCF4; SALL2; CSDC2; TAL1; LOXL2; ZKSCAN4; TERF2; ELF4; ZNF580; RSF1; HOXB2; FOXO4; SP140L; ZMYM2; BTG1; IRF7; EMX2; MAF; CERS4; OSR2; ERBB4; NFAT5; RBL2; KLF3; ZNF83; ZNF224; BCL6; NFE2L1; SIRT7; TRPS1; PHIP; HBP1; CREBL2; NCOA2; SOX3; IRF6; ZNF117; TBX21; ID2; HMGB1; MEIS1; POLR3C; SP110; KLF9; FOXO3; SPDEF; PFDN5; SNAI2; ZNF91; SP100; ZNF44; ZNF721; IRF3; SMARCC2; MZF1; FOXA1; TCF7L1; TLE2; OVOL2; RBFOX2; SRCAP; KLF13; ARID1A; MAFB; ZNF467; TRIM29; TCEB2; BNC2; ZFHX3; TAF11; CUX2; ZNF12; RFXANK; NR4A2; ZNF33B; NR2C1; RFX5; TCF7L2; SPI1; GTF2F1; PNRC1; ZNF665; SPEN; FOXN3; DLX4; BRD2; ZBTB16; PGR; BCL11A; TWIST1; JAK2; ERBB2; CEBPD; TGIF1; TGFB1I1; ID3; SCAND1; LITAF; TRIM16; ZBTB20; ZSCAN18; MEIS2; TCEA1; INSM1; FOXO1; HOXB6; HIPK1; HOXB7; GATA6; MECOM; RERE; ZFPM2; ZKSCAN1; DLX5; TRIM22; CREG1; CSDE1; NR1H2; FOXF1; PIR; FOSB; EYA2; TOX3; EHF; BASP1; ID4; IFI16; TRIB3
Down-regulation	174	PUF60; CENPF; HDAC2; IKBKAP; FOSL1; TCERG1; GABPB1; CCNA2; RUVBL1; FOXM1; HSF2; ETV1; CCNE1; CCNC; MTDH; DRAP1; UBE2I; WHSC1; CHAF1B; NCOA4; RBM14; TBPL1; REXO4; EZH2; RNF138; EGR1; SNIP1; NELFB; ORC2; BRPF1; POLR3F; C1QBP; HMGA1; MED27; BCLAF1; SFPQ; CTR9; ZNF200; HMGB2; PARP1; CBFB; PTTG1; BRCA1; BATF3; ING2; REST; ERCC2; ZMYND11; RHOA; GTF2I; C1D; NRBF2; SNAPC4; AGO2; HNRNPD; CBX3; ETV4; TRIM32; SMARCA4; PLAGL2; ZNF134; NFX1; URI1; TEAD4; WDHD1; YEATS4; ZNF143; TRIM28; E2F6; THAP1; SAP30; YAF2; ZBTB24; TBP; MED7; GABPA; BAZ1A; HMGA2; GTF2IRD1; CHD7; RAN; MED21; AATF; ING1; WWTR1; RUVBL2; CAPN15; ZBTB18; NFYA; NR1I2; DDX5; BLM; SF1; NPM1; SMARCA5; ENO1; ETV5; PIAS2; EGR3; NEDD8; PHF2; PAXBP1; ZBTB11; PSMC3IP; EDF1; RBL1; MSX1; NFIB; SOX9; EGR2; SMAD1; TAF1A; EGR4; CCDC59; PREB; MAGED1; SMAD2; ELK3; TOB1; MYT1L; HLF; MYC; KMT2B; ILF2; REPIN1; KLF6; CEBPZ; MYF6; YWHAB; NUP62; VDR; TAF5; TOPORS; XRCC6; ATF7IP; SERTAD2; ZFP64; NFE2L3; ZNF146; BHLHE40; HDAC4; TSC22D1; JARID2; MYBL2; SSRP1; MYCBP; BMI1; PCGF1; RCOR1; SUV39H1; BHLHE41; ING3; MEF2A; TCFL5; POU4F1; SATB2; SHOX2; NFKB1; TFAM; PLAGL1; HOXD1; ELF5; HEY1; SSX1; ZNF281; ZNF131; DNMT3B; HDAC9; HMGB3; PPARG; CALR; STAT1; PEG3; KDM5D