Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76286	Pf-431396	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	132	SSBP2; TSC22D3; PRDM2; AR; BRD4; IRF9; SETDB1; CHD4; ATF3; SOX2; GLI3; RB1; SATB1; TEAD3; ARID1A; SSBP3; HBP1; DAXX; ING4; TCF25; CD3D; ZNF43; CHD8; CCNT1; ZNF91; MYCL; NKRF; TCF7L1; BTG1; CDIP1; TCF7L2; TULP3; CALCOCO1; INSR; SALL2; ZNF117; ZNF12; IRF6; FOXO3; ZNF93; HMGB1; ZBTB16; TBL1X; ZIC3; CUX2; RARA; SOHLH2; MEOX1; NFATC4; HOXB2; BAZ2B; HDAC9; PNRC1; SMARCC2; JUND; RBPJ; MEOX2; DACH1; MTF2; ZNF232; CUX1; SCMH1; POU2AF1; HDAC5; NCOR2; ZNF423; BCL10; LIN28A; CREBL2; MITF; BNC2; FLI1; ZNF33B; KLF9; PFDN5; SIX3; BACH2; EYA1; ZNF665; INSM1; ZBED1; ZNF516; ZNF22; NEUROD1; SPDEF; MDM2; ZNF239; TLE4; TBX3; FOXN3; KLF7; PBX1; MEIS1; CERS6; ZNF467; KLF6; ERBB2; ZKSCAN1; ERBB4; RERE; STAT6; AEBP1; ZFHX3; HIPK3; ZNF415; NCOA2; CRYM; KLF11; ZNF331; RYBP; ISL1; ESR1; TWIST1; ST18; ZSCAN18; SIX2; HIC2; NFIB; GTF3A; PBX3; CBX6; ZFP36L1; ZBTB18; FOXG1; MYBL1; TCF4; GATA6; TOX3; SSX1; HTATIP2; MYCN; TRIB3
Down-regulation	143	IKBKAP; PMS1; HDAC2; C1QBP; TBPL1; DNAJC2; DDX5; HSF2; EED; GTF2A2; FOSL1; GABPB1; RUVBL1; ZNF23; SOX15; PIAS2; UIMC1; ZNF189; ID1; YEATS4; PITX1; TOB1; REST; PSMC3IP; MED7; SFPQ; CCNE1; CBFB; ID3; CBX3; ZBTB11; CDYL; EZH2; HNRNPD; PTTG1; CCNC; RHOA; ZBTB25; BBX; TMF1; BCLAF1; EDF1; RUVBL2; ZMYND11; MED1; FOXD1; ARID4A; HES1; RBM14; ORC2; SMARCA5; CCDC59; TBP; CTR9; GATA4; NCOA4; BIRC2; GATA1; ZNF45; KDM2A; BAZ1A; CEBPA; KLF1; TRIM32; ZNF226; IRF1; TEAD4; MYF6; ZBTB1; CEBPZ; COPS2; SUB1; BLM; SREBF1; ZNF473; TTF1; ZNF302; NR1D2; TRIP6; JUNB; BHLHE40; ING2; ZNF146; TAF10; RUNX1; HLTF; BMI1; POU4F1; ASH2L; PDLIM1; TGFB1; PAXBP1; ETV5; BRCA1; MNAT1; PURA; ING3; KLF5; ZNF576; CEBPD; NRIP1; ZBTB38; RXRA; PEG3; DR1; NAB1; BATF; IRX5; ITGB3BP; ZFP64; COPS5; ARNTL2; TCFL5; CHD1; RNF138; CHD7; SMAD6; LMCD1; BCL3; BATF3; SMAD7; UBP1; SMARCA2; STAT1; TAL1; CREG1; PPARG; KLF10; CCNA2; MYCBP; ZNF274; HOXA1; NR4A2; FOXC1; PIR; LEF1; SOX9; NFATC3; MYRF; ETS2; SUV39H1; BASP1; RELB