Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76277	Ibrutinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	83	ZNF586; ZNF544; IRF9; ZNF587; MTA1; ZNF304; BRD4; ZNF268; ZNF134; AR; ZNF43; ZNF551; ZNF423; CHD4; CIR1; ZNF195; ZNF606; ZNF135; KLF13; ZNF91; ZNF136; JUND; MEOX2; ATF2; RBPJ; ZNF264; ZNF419; BNC2; ZNF117; ZNF580; KLF7; ZMYND8; CARM1; EMX2; ZHX2; ZNF83; ZNF12; HMBOX1; TRIM22; LITAF; ZNF44; ZNF415; FOXK2; IRF6; PGR; ZBTB18; ESR1; HOXD3; HOXB2; ARID5B; ZNF165; TGFB1I1; LOXL2; OSR2; NFE2L1; ZNF331; SP110; CUX1; HDAC9; ARID1A; POU2AF1; ZNF468; TOX3; ZEB1; MEIS2; ZNF512B; NANOG; ZNF281; ZSCAN18; TFAP2A; MAF; ATF3; ZFPM2; ZBTB20; ATF5; WT1; AEBP1; RORA; EHF; NR2F6; TLE1; LEF1; TRIB3
Down-regulation	76	PSIP1; CENPF; FOSL1; MBD2; ECD; PTTG1; ATF1; EZH2; CHAF1B; BLM; CCNE1; DEK; BRPF1; CARHSP1; HES1; PSMC3IP; SMAD4; PIAS2; YAF2; CBFB; ZBTB14; HMGB2; RNF138; SMAD2; BAZ1A; LHX6; HMGA2; BATF3; TSC22D2; PREB; ZNF226; BRCA1; C1D; PAX6; TOB1; SATB2; MAFB; ING3; HHEX; NAB1; NFIB; KLF4; WWTR1; NR2F1; FLNA; PDLIM1; NR4A2; HLF; SERTAD2; NRIP1; JARID2; RBBP8; ERBB2; ELF5; TCFL5; FOXC1; HTATIP2; SIX2; CCNA2; NR2F2; TBL1XR1; SAP30; MTF2; HLTF; CREG1; VGLL4; ID1; MYBL1; NR1D2; DLX2; SUV39H1; NFATC3; SOX9; BASP1; KDM5D; PPARG