Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76276	Ibrutinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	130	TBX3; ZNF124; ZNF611; IRF9; ZNF136; CD3D; ZNF264; JUN; ZNF665; ATF3; HIC2; CNOT6; SP140L; NFE2L2; KAT2B; HOXD1; IRF6; TCF7L2; ZNF652; TCEA2; SOX2; ZNF623; KLF3; ARHGAP35; MEIS2; CBX7; ZNF160; NR4A3; REL; NR4A1; ZNF721; JUND; NCOA2; FOXF2; CDK2; NR1H2; TAL1; HBP1; PCGF3; PSMC3; ZNF44; ZNF232; NHLH1; TRPS1; ZNF331; TGS1; ID1; TAF1; ZNF12; PHIP; EYA1; ZNF239; TFAP2A; CTNNB1; ZNF33B; RBFOX2; ARNT2; ZNF43; ZNF22; FOXA1; RFXANK; MXI1; LPIN2; ZNF117; ERBB4; SIAH2; FOXK2; MYCL; TFAP2C; NFE2; ZNF467; BNC2; POU2AF1; SNAI2; TERF2; RING1; TGFB1I1; LEF1; RAD21; GATA6; EPAS1; JUP; CUX2; PHF1; OSR2; CNOT3; HOXB2; TCF7; ERBB2; ID4; MYBL1; HIPK1; SPDEF; ZNF512B; PAX6; CREBL2; NR5A2; MAF; ATN1; STAT4; ID3; HOXC10; HOXD3; BCL11A; SOX11; ZFP36L2; TRIM29; FHL2; NKX2-1; AHR; DLX2; LIN28A; MEIS1; IFI16; FOXF1; TOX; IRF1; SOX10; ZNF430; ZBTB20; MECOM; ZEB1; ZSCAN18; ETS2; WT1; ZFP36L1; SMAD6; AEBP1; ARID5B; TRIB3
Down-regulation	144	UBE2I; ARNTL; ELF1; BRPF1; HMG20B; USF2; EZH2; ING2; YEATS4; CBFB; DRAP1; PSMD9; HSF2; PHF2; CCNC; HOXA5; EDF1; CHAF1B; PMF1; JARID2; RHOA; NCOA6; KMT2B; ING1; CRY1; WWTR1; SAP30; TBP; ZNF146; ZMIZ2; WHSC1; TBPL1; CREBZF; FOSL1; RUVBL2; HNRNPD; PTTG1; SAP18; MNT; NRBF2; NEDD8; CCNA2; CTR9; EGR1; KDM2A; YAF2; HDAC1; BRD3; MSX1; FOXJ3; CAPN15; TLE4; C1D; MBD2; ZNF302; TAF10; HOXB7; BAZ1A; ZBTB24; AATF; KAT6B; ELK3; POLR2A; ETV1; PIAS2; RBM14; TOB1; MTA1; ZBTB11; SMARCA2; BRD8; MSC; NR2F2; SIX1; HTATIP2; NUP62; MEOX2; HOXC6; ATF4; ZBTB32; RNF6; TRIM28; EBF2; RNF4; VEZF1; NFIB; SMARCA4; HLTF; BMI1; BLM; ZFP64; NR0B1; BBX; MAFB; CEBPD; MTF2; CEBPA; PURA; TCFL5; EN2; BCLAF1; PREB; HMGA2; PATZ1; ZNF226; BRCA1; RBBP7; BATF3; ITGB3BP; DNAJC1; FOXC1; MNAT1; PCGF1; HMGN3; REPIN1; PBX1; GTF3A; ZBTB38; ZMYM2; BHLHE41; ATF5; BHLHE40; RBBP8; PLAGL1; ZNF267; YWHAB; ZBTB18; NFE2L3; PITX1; HOXB6; POU4F1; SOX9; SPEN; DDIT3; RBPMS; AFF1; CITED2; MYB; TSC22D1; TWIST1; CREG1; SUV39H1; PPARG; KDM5D