Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76275	Ibrutinib	GSE92742	MCF10A	Human	24h	2uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	204	TBX3; ZNF611; IRF9; GATA3; TSC22D3; TRPS1; AR; IRF7; EP300; HBP1; ZHX2; CALCOCO1; PHIP; ZNF74; ING4; ARID5A; SOX5; PNRC1; ZNF117; ZNF652; RB1; PBXIP1; ZNF512B; BTG1; SOX13; ZNF43; HDAC7; ZNF160; ARHGAP35; CHD4; ZNF44; PIAS4; ZNF688; ARID1A; RSF1; ATF3; CSDC2; JUN; SIRT7; SOHLH2; NCOA2; TCF7L1; SOX2; BACH2; KAT6B; IRF6; ZNF331; ZNF721; ZNF268; PQBP1; ZIC1; FUBP1; KAT2B; ZNF264; AEBP1; ELF4; OSR2; POLR3C; ERBB4; MGA; SP140L; ZNF623; MAF; NFAT5; WNT4; FOXK2; ZBTB20; ZNF32; ZNF195; PFDN5; TEAD3; PRRX1; SRCAP; NFATC4; CBX7; ZNF223; GLI3; BPTF; ZNF140; SLC2A4RG; ESR1; ZMYM2; HEY2; TULP3; PRKDC; EYA1; ZMYND8; KLF3; ZNF124; HOXB5; CDIP1; CREBL2; HIC2; GON4L; ZNF816; ZFP36L2; TCEA1; HMBOX1; ZNF85; ZNF224; ZNF354A; HOXB2; ID1; PRPF6; TAL1; TFAP2C; HEY1; FOXA1; SP2; SALL2; MYBL1; ZNF292; INSM1; ID4; CBFA2T2; JUNB; THAP11; GTF3A; RFXANK; ZFHX3; ZNF91; MED23; ZNF22; SP110; TRIM29; MAZ; E4F1; ZNF665; HOXC4; HOXD1; ZFP36L1; SPI1; CREB3L2; NR4A1; RERE; OVOL2; FOXN3; NR4A2; WWP1; CUX2; ZNF107; NR1H4; LIN28A; MLXIP; ZNF83; ZNF532; SPDEF; HOXB13; JUND; JUP; CTBP1; DLX5; CEBPD; NCOR2; TGFB1I1; ARID5B; GTF2F1; ZNF93; DLX4; ZNF423; PITX2; HIPK1; NR1H2; DACH1; PRMT2; SOX10; ZNF467; ATN1; ZBTB16; JAK2; TCF4; HMGB1; PHF1; CTBP2; BCL11A; GATA6; HIRA; SPEN; ARNT2; SMARCC2; CITED2; CREB1; MXI1; RORA; KDM5C; E2F3; MYCL; PBX1; TFAP2A; ZSCAN18; FLNA; IFI16; KLF11; MEIS2; FOSL2; CBFA2T3; ZFPM2; ATF5; MYB; DLX2; PEG3; CREG1; TWIST1; TRIB3
Down-regulation	184	CENPF; PTTG1; FOSL1; HDAC2; CCNA2; MTDH; PSIP1; RBM14; EZH2; CBFB; GABPB1; MED1; MED27; YEATS4; PMS1; CTR9; BRPF1; ETS1; TCERG1; PARP1; MED21; FOXM1; CCDC59; BLM; RUVBL2; CHAF1B; HNRNPD; DRAP1; REST; ERCC2; DNAJC2; XBP1; BAZ1A; ZNF614; WHSC1; PIAS2; ZNF23; TBP; ECD; ORC2; RUNX3; ZNF143; NELFB; NFKBIB; CBX3; UIMC1; NFX1; RHOA; SMAD4; YAF2; NRBF2; RUVBL1; HOXB9; TSC22D2; E2F1; REXO4; HMGA1; GTF2A2; TRIP6; ELK1; GABPA; SAP30; NCOA6; HMGA2; EDF1; MED6; MSX1; ETV1; TAF5; NUP62; ZBTB11; CRY1; SMARCA5; MYCBP; CARHSP1; BCLAF1; NCOA4; TRIM32; PDLIM1; NFYA; RNF138; SATB2; BRCA1; SFMBT1; ZMIZ2; ZBTB24; NR1I2; CCNE1; C1D; TAF9; NEDD8; THAP1; ZNF672; PURA; CHD9; ZSCAN5A; PHF2; HOXA7; ESRRA; CREB3L1; NPM1; NFIB; BATF3; POLR2A; ING1; BRD8; ITGB3BP; KMT5A; PSMC3IP; CRK; DDX5; CEBPZ; HSF2; RNF111; SNW1; CARM1; HLTF; TFAM; TOPORS; MED20; NFYB; MBD2; TRIM28; SUB1; TAF9B; KLF6; RBBP8; ZNF146; YWHAB; ING2; SMARCA2; HMGB3; TOB1; TCFL5; CITED1; EGR4; RBPMS; ZNF329; ZNF165; SMAD2; INSR; BHLHE40; MNAT1; SERTAD2; DNMT3B; SUV39H1; SIX1; LHX2; EGR2; HMGB2; MYT1L; DNAJC1; CHD7; ATF4; ZBTB38; USP16; RYBP; ARNTL2; BASP1; SOX9; TFDP1; POU4F1; SMAD1; UBP1; PLAGL1; KLF10; ZBED2; EGR3; ERBB2; BMI1; KLF4; JARID2; IRF4; HIPK3; TSC22D1; LITAF; KDM5D; PAX5; POU2AF1; ELF5; HOXA10; PPARG; NR2F6; NR1D2