Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76273	Linsitinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	53	HDAC9; MED15; DAXX; TFEC; NEUROD1; NCOR2; ATF3; ZNF423; BIRC2; PQBP1; BCL11A; ZNF43; ELF4; ZMYM2; ERBB2; SPDEF; MED14; SALL1; TAF1D; TAL1; TLE4; ZFP36L2; ZBTB16; TCF7L2; GATAD2A; MYCL; E2F5; MYB; TOX; ZBTB18; CUX2; NFE2; FOXG1; SCAND1; FOXF1; OLIG2; CREB1; ZFP36L1; TCF4; SMAD7; CALR; SPIB; CBFA2T3; POU2AF1; GTF3A; ZIC1; ZNF274; ZNF131; CTBP2; CITED2; HOXB6; NRIP1; TRIB3
Down-regulation	69	PSIP1; CENPF; SMAD3; SETD2; PMS1; GABPB1; WWTR1; SFPQ; IRX5; NCOA1; BLM; HSF2; SMARCA2; NFIC; CEBPZ; TEAD1; CTR9; URI1; NFAT5; BCLAF1; KDM2A; NFATC1; HDAC4; SAP30; PTTG1; PIR; NR4A2; NR4A3; RORA; ARNTL2; HLTF; OSR2; LMCD1; TOB1; ZBTB38; POU4F1; TFAM; ZNF281; KLF9; PITX1; ZNF331; SPEN; NFIB; NR1D2; CCNA2; KLF10; MEIS2; JARID2; SNAI2; TCFL5; PURA; NR2F2; ZFHX4; LEF1; TGFB1; HTATIP2; STAT1; IRF4; FOXN3; MAFB; FOXC1; BMI1; SATB2; TWIST1; AHR; TXNIP; PEG3; PPARG; SUV39H1