Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76272	Linsitinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	114	MEF2C; ZNF586; IRF9; ZNF544; ZNF83; ZNF606; ZNF91; ZNF264; ZNF671; ZNF268; ZNF665; NR2C1; ZNF304; VPS72; ZNF44; ZNF611; ZNF43; ZNF587; HBP1; FLI1; ZNF141; ZNF415; ZNF419; LOXL2; TFAP2C; ZNF551; ZNF345; ZNF223; ZNF350; ZNF14; ZNF85; ZNF134; ZNF135; ZNF426; ZNF117; ZNF232; SUPT6H; ZNF202; ATF2; NFATC3; ZNF266; ZIC3; ZNF444; ZFP36L2; SOX17; BACH2; ERBB2; HOXD3; ERBB4; ZFPM2; RBPJ; FOXO1; HOXD1; TOX; SP140L; ZNF331; GATA6; EMX2; ZKSCAN7; TRIM29; ZSCAN18; ZNF195; RSF1; ZNF239; ZNF93; MED14; PQBP1; ESR1; TAF7; ZNF211; ZBED2; TRIM22; DACH1; ZNF22; SRCAP; HIC2; ST18; HDAC4; ELF4; ZNF654; HOXC4; VDR; ZNF468; IRF6; OSR2; ARNT2; ZNF423; HMGN3; WT1; PBX1; PFDN5; SCAND1; LIN28A; TRPS1; ZNF160; JUP; ZFP36L1; NFE2; TCF4; IFI16; DDIT3; HOXB2; MAF; DLX2; CTBP2; PAX5; SMAD6; ID1; ID3; ZBTB16; KLF2; SOX9; TRIB3; MYRF
Down-regulation	116	CENPF; ARNTL; MTDH; MXD1; WWTR1; EZH2; ECD; REST; EED; CTR9; STAT5B; TCERG1; BCLAF1; LMO1; NCOA4; SAP30; PIAS2; PSIP1; BRPF1; ING2; NFKBIB; CREM; TBPL1; CBFB; BAZ1A; EDF1; ZBTB1; ETV1; MYCBP; NFKBIA; MBD2; MED1; ORC2; FOXD1; NFYA; REPIN1; ZBTB24; SMARCA1; TBP; BATF3; ZMYND11; PTTG1; PURA; NELFB; KMT5A; TOB1; RBM14; CRY1; URI1; CEBPA; SMARCA5; RNF138; TADA3; NUP62; PIR; HOXB7; SFPQ; SMARCA4; BRD3; AFF1; JARID2; SIAH2; RNF6; ARNTL2; ATF7IP; POLR2A; ZMIZ2; CDYL; HIPK1; INSM1; HLTF; BBX; HMGB2; CEBPZ; ZNF146; NRIP1; SMAD1; RCOR1; BMI1; SATB2; RUNX3; ASCL1; UBP1; GRHL2; SUB1; PITX1; RFX5; PDLIM1; MTF2; BHLHE40; NFIB; YWHAB; DNMT3B; KLF10; CCNA2; SMARCA2; BCL11B; CREB1; NR2F1; BCL3; JUNB; ZBTB38; NR2F6; ISL1; FOXC1; KDM5B; PPARG; HTATIP2; NR2F2; NR1H2; ELF5; CREG1; EHF; SUV39H1; KDM5D; RELB