Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76270	Linsitinib	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	110	TSC22D3; IRF9; SMAD3; FOXO4; MITF; HBP1; NRBF2; FOXO3; XBP1; RBL2; CALCOCO1; RB1; MBD1; EGR2; BTG1; SOX13; ARNTL; KAT2B; NR3C1; ZFP36L2; NFIL3; ERBB2; ZNF124; ZNF768; ZNF354A; SPI1; NCOR2; FOXA1; HDAC9; GTF2IRD1; ZMYM2; SP100; KLF9; TBX21; ZNF24; TCF25; TLE4; SOX3; IRF7; MAF; CHD9; GON4L; PAWR; ELF4; RBPJ; PNRC1; ZMIZ1; TSG101; ZNF117; DDX17; RUNX1; UBE2B; SP110; SIRT2; TGIF1; NR0B1; JUP; CNOT6; ST18; FOXO1; NCOA3; ZIC1; PBXIP1; OLIG2; LYL1; ZNF160; TCEB2; GFI1; INSM1; FOXN3; CREBL2; MEF2A; NKX2-1; SCAND1; ASCL1; SOX4; ZSCAN31; CBFA2T3; CUX2; GATA6; ARNT2; MYBL1; MXI1; ZKSCAN1; TFAP2C; ZBTB20; CREG1; TRIM16; ZEB2; NPAS2; NRIP1; MNDA; NKX3-1; VGLL4; TFAP2A; BHLHE41; RORA; PBX3; HOXB2; DDIT3; MYB; CTBP2; HMGB3; KDM5B; MYRF; HTATIP2; TXNIP; WT1; BASP1; CRK
Down-regulation	104	PSIP1; ATF1; C1QBP; RBM14; RUVBL1; HDAC2; CCNC; IKBKAP; ABT1; HES1; EED; PARP1; CCDC59; PITX1; TCERG1; HOXA7; CBFB; SFPQ; ELK3; ETS1; SAFB2; CENPF; NFIC; LHX1; BCLAF1; EZH2; REXO4; TBPL1; ZBTB1; SETD2; ENO1; CTR9; EMX2; HOXA5; TRIM32; SUB1; CRY1; ING1; ETV1; CCNA2; IL16; MECOM; ZNF3; BATF3; MLX; SREBF1; SOX17; ENY2; MSX1; NFIB; MTA1; CHD7; CHD1; TRIM28; TFCP2; YWHAB; ZNF184; BRD7; PIR; ID1; HMGB2; WDR77; EBF2; HNRNPD; MYC; MYT1L; ZNF281; HMBOX1; ZNF551; PURA; DEK; SMARCA5; EDF1; MTF2; PEG3; RXRA; RNF138; ING3; ILF2; COPS5; UBP1; ID3; HMGA2; BHLHE40; RFX5; HLF; NR1H2; MYCBP; SSX1; SMAD1; TWIST1; HOXC6; WWC1; DNMT3B; TCFL5; ATF5; BMI1; MEIS2; PDLIM1; ZEB1; HOXA10; PPARG; SUV39H1; LEF1