Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76244	Gsk-2126458	GSE92742	MCF10A	Human	24h	2uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	187	ADRB2; HDAC6; IRF9; TSC22D3; EP300; HBP1; RCOR3; PNRC1; FOXO4; CTBP1; MED15; CIR1; ZNF444; RB1; ZNF688; CALCOCO1; PRDM2; ZNF611; MTA1; TGFB1I1; PFDN5; MED16; AR; TFDP2; IRF7; TGIF1; ZKSCAN4; KAT2B; ZNF141; SUPT3H; POLR3C; UBE2B; ERBB4; KLF3; PHF1; AES; ZNF768; CBX7; MXI1; RBPJ; JUND; ZNF264; ZFPM2; ZIC1; ATF3; NFE2L1; BRD4; SOX3; ZNF331; BIRC2; PBX2; ZNF136; NCOA1; PCGF3; PAWR; BNC2; BACH1; NR2C1; NFE2; HIPK1; HOXB13; TAF11; ZHX2; ESR1; ZNF44; ZNF787; FOXJ2; CREM; MAZ; ZNF350; FOXM1; SSBP3; ZNF580; CNOT3; KLF6; SOX17; ZNF665; CDK2; CREBL2; TAL1; SP140L; PGR; EPAS1; ZXDC; KLF7; SP100; FLNA; MITF; SRCAP; ZNF467; PSMC3; TCEB2; NR1H2; RNF10; DDIT3; OSR2; CD3D; ZNF544; ST18; AIP; WT1; SPDEF; ZNF652; HOXD1; ARID1A; TSG101; ZNF91; NCOR2; HEY2; NR5A2; HMGN3; MYBL1; ZFP36L1; ZNF721; LEF1; CTNNB1; ZBTB16; TCF7L1; SCMH1; LYL1; NR4A3; CBX4; BTG1; YAP1; KLF13; TBL1X; ZNF32; ERBB2; PBXIP1; ARNT2; SP110; ZBED1; THAP7; KAT8; FOSL2; VEZF1; NEUROD1; ZNF394; AEBP1; REL; ZNF160; SIAH2; ZNF165; ZEB1; ELF4; CBFA2T3; FOS; TXNIP; ZNF423; ZFHX3; ELK4; TFAP2C; KLF11; ZMYM2; JAK2; LIN28A; NR4A2; CUX1; HOXC10; AHR; HOXC4; TDP2; TGFB1; CRYM; SALL1; ZNF415; ZFP36L2; FOXO1; CUX2; TFAP2A; ZSCAN18; NKX3-1; MLXIP; STAT6; CITED2; MNDA; JUP; INSR; TCF7; TSC22D1; ABL1; SSX1; TCF4; ZKSCAN1; ID1; TRIB3; ARID5B
Down-regulation	201	IKBKAP; PARP1; PUF60; C1QBP; RUVBL1; PMS1; CBFB; HES1; HDAC2; ELK3; E2F6; TBPL1; SMARCA5; BCLAF1; CENPF; RBM14; EZH2; SMARCA4; MYC; CCNC; CTR9; ENO1; EED; PAXBP1; MED27; PSIP1; MYCBP; TCERG1; ID2; ARNTL; NR1I2; NAB1; CEBPZ; RFX5; GABPB1; SREBF1; HNRNPD; PIAS2; ZNF200; HDAC3; BLM; FOSL1; REXO4; EGR1; ZNF143; ETV4; HDAC1; ZBTB24; ADNP; FEV; PPRC1; ZHX3; NCOA6; BRPF1; MTDH; TRIM32; MED4; EDF1; TBP; DMTF1; RBBP4; ZBTB11; DNAJC2; TGS1; PTTG1; ECD; IRX5; ZNF443; RUVBL2; HSF2; HOXA11; SFPQ; NUP62; PLAGL2; TAF1D; GATA3; TRIM24; NR0B2; BAZ1A; CNOT1; DNMT3B; SUB1; MED1; GTF2I; BRD3; PURA; ORC2; ACTL6A; ZNF189; SATB1; MED17; UBP1; RNF111; SOX9; ZFP64; CEBPA; MSX1; VDR; FOXE1; CREB5; ZNF556; ZNF146; TOB1; TBX3; ASH2L; POLR3F; PHOX2B; PREB; HLTF; TERF1; TFDP1; HMGA2; ING2; CCNE1; DDX5; BRCA1; BHLHE40; URI1; MYOD1; ZBTB1; SMARCA2; NPM1; PITX1; BBX; HMGA1; POLR2A; WDR77; ATF1; PHOX2A; TFAM; HAND1; EGR2; BATF3; MEOX2; ING3; NFYA; EGR3; TCFL5; CREB3L2; YWHAB; AGO2; BMI1; SAP30; DEK; HOXA10; TLE4; PCGF2; SCAND1; PLAG1; NFIB; NR2F2; SATB2; NPAT; RXRA; NKX2-2; NFE2L3; HSBP1; SUZ12; TFCP2; CEBPD; SMARCD2; RNF138; CITED1; ISL1; MECOM; PITX2; SSRP1; ZBTB18; ZNF267; RNF6; ILF2; HOXA5; TRIP6; FOXC1; CCNA2; WWTR1; ELF5; TRIM16; JARID2; BASP1; DACH1; CREG1; PIR; SMARCD3; THAP11; TOX3; KAT6A; RBPMS; PEG3; SMAD7; CBX6; ZBTB38; IRF4; RUNX1; NR2F6; MYCN; PPARG; ASCL1; MYB; ETS2; SUV39H1