Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76243	Gsk-2126458	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	TSC22D3; IRF9; HBP1; SUPT3H; TBX3; RCOR3; FOXO4; FOXJ3; TGFB1I1; PRDM2; XBP1; GATA3; DAXX; ATF3; CERS4; NR2C1; ZNF587; RB1; CALCOCO1; AES; EZH1; YAP1; WWP1; ING4; SOX2; CD3D; PBXIP1; ZNF611; TULP4; TGIF1; TFEB; DEAF1; ZNF75D; PHF1; ZNF688; KLF7; PBX2; CBX7; SATB1; DMTF1; ZNF623; PHIP; CIR1; TBX21; SMAD3; TCF7L1; DDX17; SP100; NKX2-1; ZNF532; MED16; SPDEF; POLR3C; HSF1; TRIP11; MTA1; PAWR; SMAD4; EYA1; CDK2; POU2AF1; ZNF91; TCEA1; TLE2; SP140L; PNRC1; IRF7; RBPJ; BIRC2; KLF6; GTF2IRD1; FHL2; AR; ZNF266; TFAP2C; ZNF264; KLF3; TRPS1; FOXF2; MED14; MAZ; CBFA2T2; SOX13; TCF7L2; SRCAP; GATA6; ERBB2; SPI1; ZNF160; INSR; GON4L; WNT4; ZNF331; TSG101; DDIT3; NFX1; PAX6; CTBP1; CTNNB1; LIN28A; MNDA; ERBB4; ZNF117; ZNF580; SALL1; ZFPM2; KLF11; HOXB13; ARNT2; HDAC5; ID4; SIX3; ZNF423; CEBPD; FOXN3; CITED2; TFDP2; ZNF721; MXI1; ZNF83; CARM1; ZBED1; JUND; KLF2; ZBTB16; CHD8; TAF11; RAD21; TDP2; CBX4; CUX2; SIX2; JUP; FLNA; ZMYM2; SMARCC2; KAT2B; ARID1A; FOXO1; HMGB1; MYBL1; LEF1; STAT6; ID1; FOS; CREG1; OSR2; IRF1; POU4F1; NKX3-1; GRHL2; ESR1; CREBL2; NR1H2; IRF6; ZFP36L2; IFI16; TGFB1; HHEX; ZBTB20; CALR; TCF4; NR4A2; DLX2; ZFP36L1; AEBP1; PAX5; LITAF; PBX3; ZKSCAN1; WT1; FOSL2; TRIB3; BASP1
Down-regulation	195	RUVBL1; HDAC2; C1QBP; HES1; PARP1; MED1; PPRC1; WHSC1; PUF60; EED; TOB1; MYCBP; GABPB1; TCERG1; PMS1; MTDH; TTF2; MYC; TAF4; ZSCAN5A; GTF2I; FOSL1; AATF; RFX7; ZBTB24; BBX; GTF2A2; TBPL1; CCNE1; CCNC; MED27; PURA; RUVBL2; BAZ1A; ZNF143; PTTG1; TBP; YY1; CENPF; WDHD1; CHAF1B; ZBTB18; NEDD8; SMAD5; ZBTB11; HOXA11; HIF1A; EGR3; ZNF614; ZNF267; EZH2; VDR; PCGF2; BRCA1; NFAT5; IKBKAP; CEBPZ; CBFB; HOXB7; SERTAD2; E2F8; HOXA5; SMARCA5; MSX1; EGR1; NUP62; ELK3; EDF1; SREBF1; ENO1; CDYL; MED21; ACTL6A; TAF5; TFDP1; PLAGL2; TAF9; PIAS2; SMARCD2; SUB1; ZMIZ2; ING2; SAP30; NAB1; TFAM; ZNF184; RNF4; CREM; RFX2; ELK1; HSF2; SMARCA4; ABT1; BLM; MEOX1; ETV1; ARRB1; SETD3; ID2; PAXBP1; NR0B1; ZNF443; MEN1; ING1; MSC; POLR2A; HOXA7; BRIP1; RBM14; HOXB6; MYOD1; EBF2; NCOA6; ZNF672; HNRNPD; ELF3; CRY1; TEAD1; MED6; ATF1; HLTF; FOXC1; BATF; RNF6; PLAGL1; RNF138; RCOR1; MAGED1; MBD2; ING3; E2F3; PITX1; UBE2L3; BCLAF1; BCOR; SMARCA2; MTF2; ENY2; ILF2; EGR4; EP400; STAT3; ZFHX4; BCL3; C1D; MNAT1; DR1; CCNA2; ZFP64; TAF9B; RYBP; MYBL2; KLF10; SOX9; IRF4; TCFL5; RXRA; SPEN; RFX5; MYCN; THAP11; ITGB3BP; LZTS1; REPIN1; ATF5; TRIM28; IRF8; KLF5; BATF3; YWHAB; TGIF2; IRX5; ETS2; SMARCB1; NFKB1; CBX6; ZBED2; ZMIZ1; EMX2; HDAC9; VGLL4; ZNF131; HEY1; TOX3; ZBTB38; ELF5; KDM5D; TSC22D1; BMI1; NR2F6; NR2F2; PEG3; HOXC6; SUV39H1; PPARG