Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76229	Doramapimod	GSE92742	MCF10A	Human	24h	2uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	122	MEF2C; SATB1; DAXX; RARB; ZNF652; ZNF160; PRDM2; ZNF768; IRF9; HOXC10; CBX7; GTF2IRD1; RCOR3; ZNF611; ARID4A; NFYC; NR4A1; AES; RBPJ; ZNF117; PA2G4; EGR3; NFKB2; SLC2A4RG; ZNF586; TGIF1; DEK; UBE2B; ZNF264; MTA1; HMGB1; EGR2; ZMIZ1; CBX4; REL; IRF8; ZNF304; NKX2-1; CNOT3; NR4A2; ZNF587; CRYM; MNDA; STAT2; ZEB2; ZNF500; HLF; ZNF331; ZNF12; CREB3L1; ELF2; ELK3; ZNF711; ZNF358; BCL10; DLX4; ZNF721; FOXM1; THAP10; HMGB2; POU2AF1; ZBTB20; ZNF551; NFAT5; CERS6; NFE2L3; TSC22D2; YAP1; PBX2; E2F8; HMGA1; TCF7; ZNF512B; TFAP2C; ERF; RUNX3; ELF3; KAT2B; SSBP3; CALR; PSMC3; RBBP4; PHF20; TRIP6; MLXIP; SOX11; HMGN3; KLF10; ZMYND8; ZNF665; ERBB2; ELF5; LOXL2; JAK2; NR4A3; MYBL1; TCF4; FOXF1; ARNTL2; MAZ; ZNF430; NPAS2; GRHL2; ZNF217; TOX3; HOXC6; CITED2; ZBED2; MYRF; SPIB; SSX1; ZBTB16; ZFP36L1; SCAND1; TXNIP; CTBP2; MAFB; RORA; JUP; IRF4; ATF5; ETS2
Down-regulation	130	PUF60; IKBKAP; SOX15; SOX17; MSX1; C1QBP; HEY1; KDM4C; YEATS4; HOXA5; HEY2; CHD7; ZNF7; CITED1; POU3F2; ZFP64; UIMC1; FOXJ3; ZBTB11; WHSC1; CREB3; DDX5; MSC; TAF10; RFC1; ING2; ID3; ZNF302; ENY2; SIRT7; TDRD3; ZNF529; MYCBP; EDF1; AATF; TAF9; GLI3; RUVBL2; NCOA1; ZFP36L2; PRPF6; PRDM10; PTTG1; ERG; MNT; INSM1; YAF2; AFF4; EYA2; PURA; NHLH2; AEBP1; TMF1; RNF4; DPF2; ZNF189; NAB1; TBL1X; MTDH; MEIS1; MED20; HOXB7; PREB; COPS5; SREBF1; HSBP1; NR5A2; TCEA1; RBBP8; MBD2; ZNF432; SREBF2; NCOA6; RNF14; ZIC1; CNBP; LEF1; SPEN; ZNF473; ZBTB32; LZTS1; TDP2; NR2E1; KLF5; BCOR; PATZ1; OSR2; CRY1; PEX2; TRIM29; PRMT2; JARID2; TAF5; SNAI2; ATF4; SUB1; ASH2L; PGR; NKX2-2; RAD21; HOXB6; POU4F1; ID4; MYCN; ASCL1; BCLAF1; CEBPG; ESR1; ZNF415; EMX2; SMARCB1; DLX2; NRIP1; TP63; TOX; NR2F1; PEG3; TCFL5; ZNF423; NR2F6; MEIS2; SOX10; BTG1; RERE; SMAD1; PBX3; ISL1; MECOM; RELB; KDM5D