Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76228	Doramapimod	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	189	E2F2; NFKB2; ZNF124; BRCA2; CBX7; JAK2; PSPC1; ZNF682; LIN28A; TBX3; REL; ZNF141; BIRC2; THAP9; ZNF695; ZNF257; MTA1; TAF1A; MYT1; CARF; LMCD1; ETV5; TLE2; TBX1; ZNF227; ZNF551; ZMYM2; ZNF273; ZNF652; BHLHE41; FOXF2; RCOR3; ATF4; ZNF43; HDAC3; ZNF426; PHIP; ASCL2; ZNF667; SOX18; SMARCA1; ZMIZ1; PCGF3; SPI1; SATB1; ZNF611; ZFP69B; ARNTL2; NKX2-1; PITX2; KMT5A; NEUROD1; ZNF573; CDK8; NFE2L3; PHF1; DEK; HMGN3; E2F5; ZNF44; PRDM10; KAT6B; ZNF177; ETV6; RBBP4; CARHSP1; HOXA7; TEAD3; SALL1; POU2F1; ZNF12; HIRA; RXRG; SUPT3H; ZIC3; ATF5; ZBED1; ZNF512B; ZNF253; ALX1; IRF2; GTF3A; HMGA1; CTBP1; MDM4; CARM1; SOX13; SP110; INSM1; ZNF93; ZNF586; ELF2; ZBTB20; IRF7; TBL1XR1; ZEB1; ZNF224; AES; SOX12; HIC2; ZNF544; CBX4; NANOG; MTF2; KLF11; CREB1; BNC2; MEIS2; CREM; TGIF1; ZNF331; MXI1; TAF9B; HOXD1; TCEA1; ZNF423; CREBL2; SP140L; ZHX2; PBX2; PBX1; GFI1B; BCL3; ZBTB16; ARID5B; PQBP1; HMGA2; THAP7; UBE2L3; REPIN1; HIVEP1; ZMYND8; FOXA2; CNOT3; BCL10; ZNF264; RBBP5; NR2C1; KAT2B; TEAD4; NR1H2; SRCAP; TP63; SATB2; IRF1; YAP1; RREB1; PGR; ZFHX3; ZNF665; NR4A2; TCF4; PATZ1; SMARCC2; BCL6; MNDA; ARID1A; LOXL2; BACH1; WWTR1; MED17; EYA2; ZNF430; ZIC1; ZSCAN18; TGFB1I1; DACH1; FOXN3; IFI16; PITX1; MAFB; ZNF91; SMAD1; MYBL1; SMAD6; TSC22D1; TCFL5; ZNF131; RORA; TCF7; EMX2; NR1D2; NRIP1; ZFPM2; LEF1; ZFP36L1; SSX1; BASP1; KDM5D
Down-regulation	193	TSC22D3; HDAC6; MTDH; ADRB2; REST; TCERG1; NEDD8; KAT2A; UBE2I; MED24; HEY1; BRPF1; NR0B2; HMG20B; ZNF384; TSC22D4; PSMD9; MED1; ATF6; WIZ; MBD4; SMARCD2; NR2F1; SETD2; VPS72; GTF2A1; GABPB1; PCBD1; ZNF536; ELK1; RUVBL2; ADNP; CTR9; TRIM25; ETV1; ZIM2; HLX; CRYM; AATF; SND1; IKBKAP; ASH2L; ZMYND11; MYNN; ZNF276; CD3D; HIPK2; TAF4; POU3F2; NFKBIB; RELA; LPIN2; ASXL1; CASZ1; MYBBP1A; HDAC9; HIVEP2; RBM14; FOXD1; FOXO4; EP400; TRAK1; HMBOX1; ZNF432; ZNF410; ID2; SMARCA2; BMI1; USF2; MYCBP; RBL2; PIAS3; EPAS1; KLF6; EGR1; NUP62; ERG; POLR3F; THRA; NR2C2; MKL2; TAF10; PHF8; DNAJC1; SERTAD2; HIF1A; SMARCD3; ZNF516; ATF1; TTF2; SSRP1; MAX; KLF7; CEBPA; RAD21; SREBF1; RXRA; MAZ; TAF9; ENY2; TRIB3; MYBL2; HDGF; PBXIP1; SMAD3; TULP4; TRIP6; HSF2; KDM2A; ATF3; FOSL1; CEBPD; CXXC1; BRF2; EGR3; MLX; RNF141; CBFB; SIX2; ZFP64; SNAI2; HMGB2; BRCA1; STAT3; LHX6; ZMIZ2; ZNF629; RBM39; ZNF14; DMTF1; TRIM28; NCOA3; FOXL2; SMARCE1; FOXK2; CREB3L2; PTTG1; TAF1D; BTG1; CHD8; RRN3; FOXO3; TCF12; SIX1; SUB1; RUNX1; NR0B1; ZNF267; GFI1; TFCP2; KAT8; MAF; TAF11; SAP30; EGR4; KLF10; WWC1; EBF2; USP22; CERS6; FOSB; E2F3; PEG3; KDM5B; FOXC1; JARID2; FOXO1; EGR2; SOX9; WT1; SMAD2; NFATC3; ID3; TP53; LITAF; IRX5; MEF2A; PDLIM1; SPEN; BATF3; KLF2; VGLL4; HOXB6; TFAP2A; NR2F2; TRIM16; SCAND1; NFIB; BHLHE40; HTATIP2; PAX5; ASCL1; PPARG