Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76220	Celastrol	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	155	STAT5B; FUBP1; DMTF1; ZNF611; ZNF83; TEAD3; NUP62; TBX21; NFKB2; BTG1; LOXL2; KLF3; KLF1; ZNF160; ZNF562; ZNF112; ZNF205; ZNF133; ZNF783; ZNF331; TLE2; JAK2; SMAD3; TCF4; TCF3; PAXBP1; ZNF692; EPAS1; LIMD1; ZNF268; ZNF665; NFX1; NR4A2; JUN; PAWR; BIRC2; CBX7; ZNF131; MXD4; KAT2B; ZNF721; HBP1; ERBB2; DLX5; TGIF1; PTRF; PRRX2; ZNF177; BTAF1; ARL2BP; NFATC3; TRIP6; UBE2B; ZNF266; WWP1; CALCOCO1; TBL1X; IRF8; ZBTB20; CTBP1; RBPJ; GTF2F1; NR2C1; CEBPZ; CDIP1; ZNF43; EDF1; SP140L; CREB3; ZNF419; ZNF358; MAF; SFMBT1; ZNF12; ZNF532; NR1H4; ZNF512B; PIAS1; YBX1; EMX2; LIN28A; ZIC1; PNRC1; ZFP36L1; THAP7; RFX5; ZHX2; NFKB1; ID4; ZNF22; TGFB1I1; ZNF580; POU2F1; ZNF415; RBFOX2; USP16; CREB3L2; BANP; CREB1; NR2F1; PAX6; DAXX; EZH2; CSDE1; ARNT2; ID1; TAF1D; CAMTA1; FHL2; TCF7; ZNF91; FLNA; IRF7; BASP1; CITED2; WWTR1; INSM1; NR1H2; BACH1; CEBPD; HIC2; IRF1; CIZ1; VDR; FOXF2; TRIM22; BCL11A; REPIN1; SNAI2; HIRA; DLX2; NFE2; SALL1; TBL1XR1; MYBL1; SOX11; EYA2; CUX1; SOX9; ELF5; NANOG; PAX5; ZFPM2; MECOM; ZBTB38; HOXA10; MXI1; ID3; CREG1; THAP11; FOSL2; CBFA2T3; STAT1; TOX3; PEG3
Down-regulation	218	TSC22D3; TCEA2; PUF60; ELF1; CENPF; ATF6; KAT5; E2F6; HDAC6; TBPL1; BRD4; MED6; TLE4; YEATS4; PMF1; REST; RARA; SREBF1; MKL2; WHSC1; HSF2; CTCF; HMG20B; TCERG1; CTR9; RLF; ETV1; MAZ; NFIC; SFPQ; CCNA2; GABPB1; RHOA; HOXB7; PCBD1; NFKBIB; ZBTB24; BRD2; C1D; C1QBP; SAP30; ARRB1; MED1; ZNF212; BLM; NEDD8; PPRC1; UIMC1; ETS1; RUVBL1; ASH2L; TCF12; HMGXB4; HES1; FLI1; HDAC1; SMAD2; SSRP1; MTDH; JUND; ZFP64; FOXM1; AATF; MNT; MAML1; SOX17; TSG101; HR; POLR2A; SIX3; ING1; PHF8; IKBKAP; SLC2A4RG; ADNP; PLAGL2; CAMTA2; HDAC9; BPTF; SAP18; SMARCD2; MTA1; NAB1; NFIL3; CCNC; TAF5; SMARCE1; MEOX1; KAT6B; PCGF2; PATZ1; MYBL2; ATF3; NCOA6; THAP1; TBP; PBX3; RUVBL2; NR2F6; KLF10; MED24; CITED1; PLAG1; RBM14; BRF2; PROX1; BRIP1; ZNF146; MED13; ZMIZ2; ELF3; PCGF1; NPM1; RNF6; ELF2; EGR1; ISL1; TOB1; MEOX2; CHD8; SOX13; ERF; NONO; MAFF; ASXL1; TCF21; PLAGL1; IRX5; TTF1; MED20; SMAD5; FOXD1; ZBTB1; MNAT1; SMARCD1; PAX9; HEY1; BATF3; HMGA1; SETD3; TDRD3; TOX; ING2; SERTAD2; E2F8; PHOX2B; CD3D; GATA4; CEBPA; TRIB3; ZBTB11; FOXO3; GRHL2; OVOL2; NFATC1; ZKSCAN1; ZNF394; KAT8; LZTS1; MLLT10; TTF2; ATF5; VPS72; HMGB3; EGR3; NFYC; VEZF1; NCOA2; NRIP1; ARID1A; ATF1; ERG; CRYM; BATF; PIR; SMARCB1; MTF2; HSBP1; EGR2; ZNF410; SIAH2; SSBP3; PRKDC; MED17; PPARGC1A; ILF2; ENY2; TRIM28; TFAP2C; COPS5; HOXB6; JUP; JARID2; ZNF267; ZMYM2; NLK; SPEN; ZMIZ1; SIX1; TCFL5; YWHAB; HHEX; FOXN3; PEX2; AFF1; ASCL1; SSX1; BMI1; DNMT3B; NR2F2; TWIST1; KDM5D; RBPMS; CALR; SUV39H1; FOSB; PPARG; MYRF