Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76195	Afatinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	197	TBX3; IRF9; ING4; CALCOCO1; ZHX2; TSC22D3; TFEB; OSR2; SSBP2; ZNF768; CBX7; BTG1; CSDC2; ARID5A; TEAD3; ZNF688; PNRC1; MXI1; IRF6; TGFB1I1; CERS4; PRDM2; ZNF571; ZKSCAN4; ELF1; SOX5; ZNF141; ZNF652; TFAP2C; ZNF350; CDK2; KAT6B; ZNF611; PSMD9; YEATS2; EZH1; MED15; ZNF444; RARG; TRIM29; MTA1; PBXIP1; LITAF; PHF1; CHD9; ZNF623; AR; SOX2; WWP1; SETDB1; RB1; TRIP11; TP63; TRPS1; REL; SP140L; SUPT4H1; SP100; RSF1; KLF13; ZBTB16; PSPC1; FOXI1; MEIS1; SP2; ZNF91; ZNF112; KAT2B; FOXJ1; AES; TCF7L2; ZNF268; MEIS2; PBX1; CIR1; PFDN5; RING1; PAX5; FOXE1; TSHZ2; HDAC5; THAP11; ZFHX3; ZNF665; HSF1; TCF12; ZNF331; YBX1; ZFP36L2; ZNF304; ESRRA; BTF3; TGIF1; EPAS1; HIC2; JAK2; EYA2; SOX3; ZNF423; POU2AF1; ZBED1; TCF4; STAT2; CNOT3; JUP; NFE2L1; ZNF117; SIRT2; CBFA2T2; PHIP; SMARCC2; GATA6; SOX13; YAP1; ZNF232; TCF25; ZNF12; ATF4; CREBL2; ATF3; MED13; CNBP; ZNF557; PAWR; HMGA1; KLF3; SALL1; ESR1; ARID5B; TRIM22; ZNF394; INSR; TRIM24; SRCAP; TCF7; ZNF266; CBX4; MECP2; NR2C1; BCL6; SP110; ZNF512B; ZMYM2; THAP7; NCOA2; ZNF83; HBP1; STAT6; LYL1; ZKSCAN1; SOHLH2; MAF; ATN1; HOXA10; PHOX2B; EHF; FOXA1; NR1H2; HOXB13; ZNF195; PRPF6; KLF11; TAF7; ARNT2; ZNF264; TXNIP; TCF7L1; FOXN3; INSM1; HDAC4; ZNF131; ELF4; ARID1A; MECOM; RBM39; PBX3; CUX2; MLXIP; CTNNB1; ZMIZ1; ZFPM2; SCAND1; LEF1; CREB1; ERBB4; MNDA; FOXO1; HHEX; NKX3-1; IFI16; ZFP36L1; KLF4; TSC22D1; CREG1; WT1; AEBP1; ETS2
Down-regulation	179	CENPF; CCNA2; FOSL1; PTTG1; HOXB7; GABPB1; MED1; EZH2; HDAC2; RUVBL1; CCNC; UBE2I; BLM; HLTF; BAZ1B; MTF2; DRAP1; DNAJC2; CHAF1B; HMG20B; TCERG1; WHSC1; ASH2L; EGR3; C1QBP; SMARCA4; CTR9; PARP1; CARHSP1; CCNE1; RBM14; MTDH; RUVBL2; RHOA; PSIP1; REST; FOXM1; WWTR1; SIX1; CBFB; PSMC3IP; RNF4; ETV1; SFPQ; HOXA7; MED7; SMARCA5; PPRC1; BRCA1; BATF3; TBP; NUP62; MSX1; EED; XBP1; BCLAF1; ATF6; MEOX2; CAPN15; CEBPZ; ELK1; TAF9; AATF; ONECUT2; WIZ; TRAK1; DNAJC1; EGR1; MNX1; EBF2; IKBKAP; TRIP6; CBX3; ALX1; NFIB; HSF2; RFC1; ELK3; HNRNPD; DNMT3B; LHX1; SSRP1; TAF10; ING3; EGR4; HMG20A; SUZ12; GMEB1; MYBBP1A; NFAT5; RXRG; ARRB1; NR1I2; HMGB2; POLR3F; RBBP4; BMI1; TFAM; KDM2A; BAZ1A; CHD7; KMT2B; RBBP8; ZBTB24; MYT1L; HOXC10; TULP4; ING2; ZIC1; ZNF267; PREB; JARID2; WDHD1; TEAD1; MYBL2; SMARCD3; TFDP1; RLF; WWC1; ZFHX4; TMF1; CRY1; GATAD2A; MNAT1; ENO1; SMAD1; TAF1D; SF1; RNF138; POU5F1B; KLF6; TSC22D2; C1D; ID3; BRF2; HMGA2; POLR2A; USP16; CHD1; E2F3; BHLHE40; HMGB3; ILF2; MLX; EN2; SUV39H1; SAP30; HOXB6; BBX; MYCBP; KAT6A; ERBB2; SERTAD2; EGR2; TBL1XR1; LOXL2; HOXA1; ANKRD1; IRX5; RFX5; SATB2; LZTS1; RBPMS; STAT1; NR2F6; SIX2; TWIST1; KLF2; KLF10; PURA; ZBTB18; PPARG; NR1D2; ZEB1; ZBTB20; KDM5D; HTATIP2; HOXC6; BASP1