Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76194	Afatinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	136	TSC22D3; IRF9; FOXO4; BAZ2B; HBP1; ADRB2; CALCOCO1; HDAC6; ZNF83; TRIM29; MED15; EP300; ID2; PHIP; FOXO3; PQBP1; EZH1; ZNF611; UBE2B; MXD4; ZNF266; ING4; PBX1; ELF1; NCOA1; BTG1; ZHX2; KLF9; ZMYM2; IRF7; AR; NR3C1; TLE4; ERBB2; PNRC1; OSR2; ZNF768; MED13; PFDN5; IRF6; MAF; ZNF358; CBX7; ESRRA; ATF3; ZNF160; BRWD1; SPEN; BRD4; NFKBIA; ZNF711; TEAD3; TCF25; RFX5; JUP; ELF4; TCF7L1; ZNF195; DLX2; SNAI2; FOXO1; TFAP2C; ZNF12; NCOA2; MITF; TAF1D; BBX; SP110; NFE2L1; LITAF; DACH1; SAP18; TBL1X; ZBTB16; SCAND1; ZNF331; ZMIZ1; TCF7L2; BCOR; ZNF264; SOX3; RBL2; PLAG1; SMARCA2; WNT4; CHD1; HDAC9; POU2F1; PBXIP1; ZNF580; TXNIP; NCOR2; ZNF721; HTATIP2; RERE; PDLIM1; ARID1A; KLF4; AES; MEF2A; ZNF91; ZNF665; CEBPD; MEOX1; HMGN3; CREB3L2; ZKSCAN1; TLE1; COPS2; ZFP36L2; TFAP2A; CSDE1; TRPS1; MYCL; TOB1; ZEB2; HEY1; CUX2; RUNX3; CUX1; SALL1; DDIT3; CBFA2T3; TRIM16; POU2AF1; FOXN3; TOX; MXI1; ZSCAN18; FOSL2; MEIS1; ST18; TOX3; MAFB; BASP1; NRIP1
Down-regulation	111	CENPF; FOXM1; UBE2I; PTTG1; CCNA2; HMGB2; FOSL1; HDAC2; WHSC1; EZH2; CBFB; HES1; ETV1; C1QBP; WWTR1; BLM; PARP1; BATF3; ACTL6A; MYBL2; TBPL1; CCNC; HMGXB4; ZNF263; SFPQ; ARNTL2; MED21; BRCA1; ETV4; ECD; BCLAF1; MED27; GTF2A2; MXD3; PSIP1; CARHSP1; GATA4; CHAF1B; WDHD1; RBM14; RNF138; HNRNPD; ELK3; DEK; RXRG; IKBKAP; TTF1; DNMT3B; TBL1XR1; NFYA; CBX3; TAF1A; EGR2; NR4A1; PRRX1; DDX5; CCDC59; NELFB; ZBTB1; TBP; ILF2; URI1; RUVBL2; HOXC10; DR1; PBX3; EN1; EGR3; RAD21; REPIN1; NFE2L3; AGO2; HMGA2; PHOX2B; YWHAB; NFIB; EGR4; SUB1; SHOX2; HLF; PATZ1; NR1H2; RBBP8; ZBTB18; ZBED2; FOXA2; HLX; ING2; SAP30; WDR77; CDK9; HOXC6; TFDP1; FLNA; MYT1L; SUV39H1; HOXB7; BHLHE40; HAND1; ISL1; SMAD1; ZNF281; ZNF274; AHR; HMGB3; KLF2; TCFL5; IFI16; SMAD6; PEG3; KDM5D