Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76193	Afatinib	GSE92742	MCF10A	Human	24h	2uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	128	TSC22D3; ADRB2; ING4; IRF9; HBP1; TBX3; CSDC2; ZNF768; FOXO4; TRIM29; IRF6; ZHX2; OSR2; TEAD3; NCOA2; ZNF611; TCF7L1; PAWR; ARID5A; WNT4; CALCOCO1; VPS72; CHD4; PBX1; ZNF688; SIRT7; EVX1; ZNF268; GATA6; CREBL2; ZFP36L2; UBE2B; FOXO3; IRF7; EZH1; JUND; NCOR2; AR; ZNF224; CBX7; COPS5; SOX17; BIRC2; MAF; ZNF140; ZNF512B; SUPT4H1; ID2; MYCL; TCEA1; ERBB4; ESR1; SCAND1; ZNF266; DACH1; PBXIP1; RNF14; NFATC4; TRIM16; ZNF358; THAP11; SNAI2; TFAP2C; ATF3; MAFB; OVOL2; ZNF226; KLF9; SOX13; CEBPD; HMGN3; CUX2; ZNF44; SPEN; CENPB; ELF4; VEZF1; MEIS1; SP140L; TOX; INSM1; PNRC1; PDLIM1; SRCAP; NR5A2; JUP; TFEC; EMX2; SIRT2; TLE1; PQBP1; SALL1; ZNF91; PRKDC; ZBTB16; SP110; ZNF652; AES; ZNF160; MYRF; PHF1; DLX5; PFDN5; TP63; CNBP; THAP7; DLX2; TAL1; TRPS1; JUNB; ATF5; KAT2B; FOXG1; E2F5; WT1; SSX1; CCNH; KLF11; TFAP2A; ID4; CREG1; LEF1; FOSL2; AEBP1; SOX9; TWIST1; TOX3; TRIB3
Down-regulation	138	CENPF; PTTG1; CCNA2; FOSL1; GABPB1; HDAC2; FOXM1; WHSC1; EZH2; WWTR1; ETV1; HMGB2; HES1; UBE2I; PARP1; EGR3; RUVBL2; REST; RUVBL1; CCNC; BLM; RBM14; MTF2; DEK; RNF138; MED1; ECD; CHAF1B; ETV5; TCERG1; HMG20A; BRCA1; WHSC1L1; ZBTB18; ETS1; BCLAF1; ELK3; RHOA; HOXA5; TBL1XR1; NCOA4; MXD1; NFYA; PSIP1; CBX5; ZNF273; NUP62; BATF3; HMGA2; MTDH; ZBED4; MAGED1; RXRG; IKBKAP; RNF4; CAPN15; CCDC59; CNOT2; WDHD1; ZNF135; ARRB1; RBPJ; DNMT3B; FOXJ3; URI1; CLOCK; TAF1A; NPM1; EGR2; DEAF1; EDF1; PEG3; NFX1; ZEB1; SMARCA1; RAD21; ASXL1; EGR4; HLTF; SMARCA5; ENO1; TRIM28; HSF2; CBFB; HIF1A; HMGXB4; ZNF432; TTF1; PIAS2; BRIP1; KLF6; HOXC10; HNRNPD; SMAD1; MSX1; SFPQ; TRIM32; CNOT6; C1D; ITGB3BP; KLF10; ILF2; NFIB; BHLHE40; SAP30; NEUROD1; CEBPZ; EBF2; MYT1L; NKX2-1; SMARCE1; KDM5D; TRIP6; SUV39H1; SIX1; BAZ1A; TAF1D; NR3C2; ING3; ZNF146; NR2F2; HMGB3; CREB3L2; SMARCA2; MYBL2; IRX5; SERTAD2; CREB3L1; ZNF274; ZBTB38; TSC22D1; SMARCD3; MYCBP; SATB2; CALR; AFF1; PPARG; ETS2