Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76188	Azd-5438	GSE92742	MCF10A	Human	24h	10uM	EID0438

Response Information :

Types	Number	Response transcription factors
Up-regulation	215	ZNF586; IRF9; AR; ZNF304; ZNF264; ZNF350; ZNF587; ZNF136; ZNF134; ERBB4; NFATC4; SMAD3; ATF3; FOSL1; ZNF419; CIR1; ZNF688; ZNF551; ZNF552; ZNF268; ZNF623; ZNF432; ZNF324; ZNF154; ZNF562; HOXB1; SOX17; ZNF816; ZNF682; PAX6; NHLH2; ZNF529; SOHLH2; ZNF12; ZNF544; SP140L; ZNF671; VENTX; TBX3; ZNF273; EGR1; ZNF211; ZNF195; ZNF573; ZNF91; ZNF611; ALX4; KLF13; ZNF7; RNF2; ZSCAN32; ING4; ATF2; ZNF215; VPS72; ZNF232; ZNF117; ZNF44; RCOR3; ZNF668; SUPT4H1; CDK2; ZNF528; ZNF14; ZNF43; ZNF468; ZNF222; BNC2; BRD4; ZNF83; ZNF764; SP2; ZNF239; ZNF331; ZNF35; SIRT7; CUX2; PRDM2; ZNF266; NEUROD1; ZNF329; SUMO1; SOX2; ZNF3; GMEB2; TAF4B; ST18; FEZF2; PRRX1; RLF; ZNF223; ZNF512B; THRA; SALL2; HOXD1; ZNF557; HBP1; HOXD3; WT1; ZNF8; PHF1; CDC5L; ACTL6B; ZNF124; CDIP1; JUP; SIN3B; MDM4; TULP3; EYA2; ZNF45; LOXL2; ZNF606; TRPS1; ZNF84; SRCAP; ZNF580; HDAC9; BHLHE40; JUND; ZNF394; ZSCAN18; ZNF467; ZNF787; ZNF667; HHEX; ZNF180; DLX2; ESR1; DNAJC2; NR1H2; PFDN5; ZNF654; KLF7; CNOT3; DDIT3; LITAF; TAF11; KLF10; LIN28A; SIX6; ZNF415; HIC2; MEIS2; ZNF665; SPDEF; SP110; CTNNB1; IRF7; ELF4; HOXB5; MAFG; TFAP2A; SP100; THAP10; KLF11; ELK4; MNDA; ZNF426; TAF9B; MECP2; NR5A2; PEX14; NR4A3; TFAP2C; ZNF473; RSF1; ZNF93; ZNF274; GON4L; KAT2B; ZNF165; ZFY; ZNF835; ZIC1; NKX2-2; BHLHE41; ZBED2; TFEC; FOXF2; ZFPM2; CBX4; EGR2; SHOX2; PBX3; MYRF; IRF8; SIRT2; RBM39; MYCL; CCNH; DLX5; IRF6; TAL1; GATA6; TDP2; DACH1; NANOG; TWIST1; NCOA2; HOXB2; SCAND1; MXI1; CEBPG; ZNF593; NRIP1; ARID5B; INSR; STAT1; ZFP36L1; HOXB6; MYBL1; KDM5D; FOSB; TRIB3
Down-regulation	265	TSC22D3; MYC; IKBKAP; HMG20B; HDAC2; NFIL3; CCNA2; CENPF; EZH2; ELF1; RBM14; ATF6; HMG20A; MTDH; PSIP1; GABPB1; PTTG1; PARP1; SMARCA4; SMAD4; TCF20; MBD2; CBFB; PHF2; CARHSP1; EED; FOXO3; BAZ1A; RFX5; SMARCC1; TP53; BRD3; ETV1; POLR2A; ATF1; UBE2I; CDK7; TBL1X; BLM; MXD4; FOXO4; ELK1; TCF12; NCOR2; USF2; PURA; WHSC1; SREBF1; ADRB2; STAT5B; SMARCD2; ZNF672; MKL1; SMARCA5; SAP30; CEBPZ; RBBP4; HNRNPD; SIX2; ORC2; TLE4; TRIM27; BBX; CTR9; BAZ1B; SMARCA2; KLF2; TRIM25; CREBZF; ARID4A; MAGED1; ZNF282; DEK; CHAF1B; CASZ1; HES1; KDM5A; HDAC6; STAT6; YAF2; SP3; ECD; HOXC6; HIVEP2; ZBTB24; NFKBIB; TRIM32; SIAH2; CEBPA; MED1; FOXD1; NR2F2; BRD8; TSC22D1; HLTF; ID2; ENO1; ZBTB38; CHD3; IRF2; PCGF2; GTF2I; TAF1D; ZBTB1; BRCA1; DEAF1; RNF111; ING2; CNOT1; KLF4; PHF8; PML; PNRC1; PAWR; TLE1; KDM2A; TBL1XR1; RBBP7; TSC22D2; PATZ1; ZNF692; SREBF2; NPAT; HOXA5; DDX54; BRPF1; CEBPD; ETV4; NELFB; ELK3; CREM; BCLAF1; UBP1; NPM1; ADNP; BAZ2B; LIMD1; KMT2B; ESRRA; ZNF516; PITX1; ETS2; GTF2IRD1; ASH2L; MEOX2; SFPQ; LPIN2; UBE2B; JARID2; SF1; ARID4B; SMARCE1; DNAJC1; HLF; NCOA4; ERG; CHD1; WWTR1; TADA3; BCL6; PBRM1; CXXC1; ATF7IP; MNAT1; NFKBIA; MSX1; FOXJ3; EP400; CBX3; NR4A1; HOXA10; EBF2; NR3C2; ARRB1; ZHX2; HMGB1; NFAT5; CHD7; EDF1; ZNF189; SMAD5; CRK; BACH2; EYA1; DPF2; ZNF292; YWHAB; CTBP2; NR1I2; CDK9; MYOD1; PRMT2; NCOA6; ZZZ3; HMGB3; DDX17; RCOR1; BTG1; SETD3; BCOR; VGLL4; ABL1; ZMYM2; RBPMS; NAB1; TRIM28; RBBP5; ID1; SIX1; CBX5; CUX1; MAZ; NFIB; TFCP2; HMGB2; MEF2A; HOXB7; SPEN; FOXO1; SOX11; ZNF131; NFATC1; FOXC1; BMI1; VEZF1; ZNF146; NLK; SUZ12; E2F5; HTATIP2; ERBB2; AFF1; SOX4; TCF4; PRKDC; ID3; ZBTB16; BATF3; HIPK3; TFDP1; TXNIP; MLXIP; KAT6A; BASP1; BCL11B; TOB1; NR1D2; TRIP6; MTF2; PAX5; DNMT3B; TRIM16; RUNX1; NFKB1; IRF4; ZBTB20; TOX3; PPARG; CREG1; SMAD7; FOXN3; ELF5; LEF1; ASCL1; PEG3