Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76167	Ruxolitinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	150	FOXO4; TSC22D4; TCF15; AATF; MLXIPL; TAF10; HMX1; TCF25; ZNF473; ZNF226; MYOG; ERCC2; ZNF646; FOXI1; BLZF1; ELK1; HCFC2; LDB1; CCDC59; MAML1; SIRT2; UIMC1; ZNF222; ID3; ITGB3BP; RB1; ZNF205; ZNF112; MEF2D; HSF2; MED17; PDLIM1; ETV5; MNAT1; RNF14; TDRD3; ERF; FOXA1; RSF1; PEX2; DDIT3; TTF1; RNF6; ATF1; HEY1; THAP1; HOXA5; GABPA; VEZF1; APBB1; DEAF1; DPF2; ILF2; RNF111; MAFF; ZNF576; UBE2I; ZNF165; XRCC6; KAT5; EGR4; MDFI; RRN3; EYA2; RBBP4; CRTC1; ZNF143; ECD; TAF9; TOB1; RLF; MBD2; ZNF232; MLX; USP22; HTATIP2; ETV4; USP16; FOXO1; TSC22D3; TP63; BCL10; NPAT; NRIP1; ELF1; CBFB; ZBED4; YEATS4; MED27; ACTL6A; BRD8; CTR9; CITED1; BAZ1A; ZNF574; RUVBL2; ATF4; ASCL1; ARID5B; COPS5; PTTG1; AIP; PMF1; NR4A1; SFPQ; CDK9; UBE2B; ZMYND11; STAT6; MED4; CCNH; TBP; TSC22D1; ATF7IP; MED1; CRK; TFCP2; ZBTB11; SREBF1; LITAF; RFXANK; RUNX1; NFE2L1; EGR3; SUZ12; KLF2; CCNC; BMI1; COPS2; TCFL5; DLX2; SOX9; ARID4B; CEBPD; YAP1; SATB2; ID1; IKBKAP; RHOA; ZNF281; FOSL1; ASH2L; ID2; HMGB3; HOXD1; STAT1; TCERG1; ATF3; POU2AF1; CEBPB
Down-regulation	147	GTF2I; RORA; MYBL1; NEUROD1; TRIM25; SP3; MYCL; FOXN3; NFE2L2; RARG; FOXM1; MYCBP; KDM5C; EYA1; LMCD1; ZIC3; ZNF611; SSBP3; KAT2B; PCGF3; CD3D; CALCOCO1; ZNF44; TFAP2A; IRF6; KLF3; ATN1; PAX6; PHIP; STAT4; FOXJ2; BACH1; CNBP; MLXIP; TRIM16; TFCP2L1; NFATC3; ZNF536; IRF7; DAXX; NFKB2; ZNF43; FOXF1; TRIM24; ZNF253; ZNF3; ZNF329; ZNF552; BHLHE40; UBP1; ZNF654; NR2F6; OSR2; ZNF264; NKX2-1; CALR; MNDA; ZNF160; ZBTB20; LIN28A; ZNF273; ZNF665; PRDM1; HHEX; MEIS1; SOX2; PHF20; ZNF136; ZNF816; GATA6; TFEB; DACH1; ZNF652; CREB3L2; ZIC1; PRDM2; IRF5; TBL1X; KDM5D; ZNF587; GRHL2; ARID1A; CREB3L1; ZNF512B; NFIB; PEG3; ELF3; ERBB4; ESR1; HLX; ZNF148; KLF4; ZFHX3; BBX; FOS; SMARCA1; IRF9; NR3C2; RREB1; TCF7L1; EHF; AR; E2F2; CREM; ZNF586; VPS72; REL; HMGN3; SALL1; CARM1; TCF4; ZFPM2; TXNIP; EGR2; ZNF721; MYCN; NFE2; CBX4; EN1; ZSCAN18; SIAH2; WNT4; CBX6; SATB1; HIC2; GATA2; JUND; ZBTB38; GATA3; DMTF1; PSIP1; ZNF423; MAF; SCAND1; IKZF1; ZMIZ1; TBX3; ZEB1; WT1; PAWR; RBPMS; KAT6B; MEIS2; SOX10; ZNF331; THAP11; BASP1