Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76165	Ruxolitinib	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	144	TAF10; TTF2; HDAC9; PHF8; MLXIPL; PCBD1; POU3F2; HDAC6; AATF; BAZ1A; CREB3; MED1; MED17; ZNF143; ELK1; ZNF576; RNF141; ID3; SAFB2; CCDC59; ZNF646; BAZ2A; TDRD3; EGR1; TAF4; RFX7; ZNF432; PHF2; RNF111; ZNF83; UIMC1; ZNF84; RNF6; ZNF302; GLI3; ATF1; STAT6; RYBP; HOXA10; KMT2B; HOXA7; TAF9; YEATS4; ZBTB7A; MLX; PATZ1; VEZF1; CITED1; RFX5; HOXA5; ZNF430; NR1I2; ZNF384; MAFB; MDFI; ACTL6A; MBD2; EP400; NCOR2; TTF1; ZBED2; PMS1; BAZ1B; ARID4B; BAZ2B; SOX15; ETV1; ZNF140; TFAM; RB1; MTF2; HTATIP2; ETV4; ZNF692; ZNF32; ZNF274; ZNF12; ZNF195; SUPT4H1; BACH2; USP22; LEF1; HOXD11; MAZ; ITGB3BP; HEY1; TRIP6; HMGA1; ZNF532; OLIG2; TBP; IFI16; SMARCA2; PMF1; BRF2; KAT5; CRK; ZHX2; PSMD9; KLF7; C1D; ASH2L; UBE2I; TSC22D3; BMI1; ATF7IP; ZBTB11; MED6; DPF2; BCL6; PCGF2; EMX2; PCGF1; TFCP2; CUX2; BIRC2; PAX5; PBX3; BCL10; NEDD8; KAT2A; EHF; SND1; DDIT3; EZH2; FOSB; TCFL5; SREBF1; NR2C1; ELK3; SPEN; TCERG1; LOXL2; TSC22D1; TLE1; ZBTB18; PTTG1; VPS72; IKBKAP; TCEB2; FLNA; ATF5; ZNF91; ID1
Down-regulation	131	RORA; LMCD1; NFE2L2; SOHLH2; NFKB2; ZNF611; PUF60; RBPJ; OSR2; TCF7L1; HMGB2; PLAGL1; TGIF2; PHIP; GATA6; KAT2B; MAF; ZNF711; MYCL; HOXC11; GTF2I; CREB3L1; E2F2; SOX3; ZNF701; ZNF623; ELF3; DAXX; KLF3; SMARCA1; PCGF3; TEAD3; RUNX3; URI1; SSBP3; ZNF331; IRF7; KDM5D; OVOL2; ZXDC; ZNF44; AR; NR3C2; DACH1; TBL1X; TULP4; CDYL; MEOX2; ESR1; GRHL2; ZNF160; PRDM2; PHF20; ERBB4; FOXF1; ZNF3; SP100; NFATC3; RNF4; ID4; MNDA; REL; TXNIP; ZNF665; TCF4; FOXF2; RARG; PRDM1; NR4A3; NR1D2; NR1H3; ING2; NR4A2; IKZF1; RREB1; STAT4; CREM; NR5A2; THAP11; HLF; HHEX; NCOA1; YWHAB; ZFPM2; PAWR; IRF6; CREB3L2; HLTF; PHOX2B; PBXIP1; ATF4; FOSL2; ZNF512B; ZNF721; IL16; SOX2; PLAG1; WT1; BHLHE41; TGFB1I1; IRF4; SOX10; RBBP7; SIAH2; CARM1; HSF1; IRF9; CBX7; TRPS1; TOX; ZNF586; GATA2; SALL1; XBP1; TCF7; ZNF264; HIC2; KLF4; KDM5A; DLX5; TBX3; GATA3; KLF13; EGR3; DMTF1; MEIS2; CBX6; TFAP2C; NR2F2; FOXG1; HOXC6