Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76164	Ruxolitinib	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	125	TAF10; TTF2; ZNF195; GLI2; DDX5; CHD9; TERF2; LEF1; TRIM27; DR1; MTDH; EED; PATZ1; ILF2; RFX7; NCOR2; POU3F2; SUPT4H1; HAND1; TSG101; MNAT1; YEATS4; VEZF1; ZNF143; ZNF84; IKZF5; CRY1; MED1; MED27; USP22; KLF9; HOXA5; PCGF2; BACH2; ZNF134; ZNF302; MED24; HDAC9; UBE3A; ZNF669; ZKSCAN1; ID3; CBFB; TSC22D2; ATF1; ZNF32; ZNF135; BCL10; CCNC; TFEB; FOXN2; ZBTB1; MLX; ZNF551; TFCP2; KLF6; SMARCA2; HMGA1; MED13; ZNF394; LITAF; HOXA7; NPAS2; UBE2I; RNF14; ZNF140; ZNF12; ZFP36L2; YWHAB; NPAT; ARID4B; ZBTB11; ZFX; PAX5; ZNF281; RFX5; IFI16; TBP; ZNF544; BAZ2B; PSMD9; ZNF573; MMS19; MTA1; ELK3; BMI1; ASH2L; ABL1; ZNF83; TSC22D1; C1D; CHD7; NEDD8; HTATIP2; ZNF652; FOSB; FOXO1; PNRC1; SND1; COPS2; RBM39; STAT1; ZNF586; MEOX1; TCFL5; REPIN1; SUZ12; LOXL2; ZHX2; HEY1; ZNF146; STAT6; ETS2; PBX3; SMAD7; TOX3; TCERG1; CRK; TCEB2; CTBP2; SMAD3; IKBKAP; MAFB; ZNF91; FOS
Down-regulation	117	SOHLH2; TBL1X; MXD1; OSR2; PCGF3; NFKB2; PHF1; SP3; MNDA; NR4A2; RORA; HLTF; CREM; HLF; ZNF331; PRDM2; OVOL2; EYA1; ZXDC; DAXX; ESR1; ZIC1; ERBB4; FOXE1; NKX2-1; ELF3; ZFP36L1; FOXF2; SMARCA1; SALL1; HOXB5; DBP; RNF4; FOXC1; CCNH; NR3C2; RBBP7; TXNIP; TCF7L1; GRHL2; JAK2; TULP4; TGIF1; FLNA; EPAS1; NFATC3; CXXC1; ZNF148; HMGB2; RARG; TCF20; KDM5D; E2F2; MAF; PEG3; AFF1; HOXD1; KLF10; ATF4; HOXB2; DLX5; PRDM1; PBXIP1; NR1D2; PIR; ETV5; CBX7; KLF3; CREB3L1; FOXF1; BHLHE41; NR1H2; SOX5; MYBL1; MYCL; HOXC10; AR; FOSL2; ST18; WNT4; HMGN3; HIC2; IKZF1; NCOA1; HNRNPD; TLE2; TCF4; EYA2; NFAT5; ING2; MECOM; ID4; CEBPD; SPEN; HOXD3; MAGED1; ZNF160; TGFB1I1; TGFB1; CREB3L2; IRF4; CITED2; TRPS1; GATA2; ZNF512B; BCL11A; ATF5; CBX6; NKX3-1; HHEX; KLF4; GATA3; BASP1; FOXG1; KAT6B; TBX3; MEIS2