Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76163	Canertinib	GSE92742	MCF10A	Human	24h	0.08uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	151	INSM1; SSBP2; ZBTB16; RSF1; BTG1; ZIC1; MED1; HDAC6; NKX2-5; TTF2; DACH1; SIRT7; TRIM16; EWSR1; TSC22D3; SP2; ZKSCAN1; PRKDC; LEF1; ZNF217; THRAP3; FOXI1; CBFA2T3; HBP1; PNRC1; NCOA2; BAZ2A; ZNF768; NCOR2; BRIP1; TOX3; HDAC5; CHD9; FOXO4; ST18; RBBP5; KDM5B; KLF9; LITAF; SUPT3H; FOXO3; TRIM29; HDAC9; ARL2BP; ZNF224; NPAS2; ZIC3; MAML1; ZHX2; ZNF688; RBL2; FOXA1; JUP; NEUROD1; MDM4; ZNF611; OLIG2; PBXIP1; RRN3; MAZ; KAT2A; MAFF; UBE2B; CERS6; CSDE1; ZBTB20; NR0B1; STAT1; SREBF2; AES; PBX3; MLXIPL; TCF25; ZNF292; CREG1; PRMT2; PIAS4; ZBTB7A; RFX7; ERBB2; MMS19; CUX1; SALL2; UBE2I; ETS1; NHLH2; NAB2; BRD2; LOXL2; BAZ2B; EPAS1; NR2F1; ZNF24; BCOR; SREBF1; UBE2L3; NRIP1; AEBP1; GATAD2A; CREBL2; CUX2; ZEB2; ATF6; TSC22D2; DLX2; ZNF573; TERF1; CITED1; ARID4B; PBX1; TCEB2; THRA; HIPK1; SPDEF; CALR; PRPF6; FOXD1; SOX9; IRF9; MEIS2; BCL10; ZMIZ1; IKZF1; HES1; PSMD9; SND1; ZEB1; HOXB2; RUNX1; RAD21; MTA1; HOXA5; HEY1; CLOCK; PDLIM1; FLNA; FOXF1; ZNF160; ATF5; ASCL1; CCNH; CEBPD; BMI1; SHOX2; BCL11A; ACTL6A; ID1; MTF2; ZNF721; CRK; POU2AF1
Down-regulation	215	TCEA2; CCNA2; CENPF; FOXM1; GTF2A2; RBPJ; SIAH2; ZNF133; TRIM32; DDX54; HMGB2; PCGF3; KDM5D; TGIF2; DNMT3B; THAP10; MXD3; BATF3; PTTG1; ZZZ3; ZNF329; ZNF282; CDYL; LMCD1; RNF4; THAP1; TBL1X; ELF5; USP21; DNAJC2; CCNE1; EZH2; DRAP1; ENO1; RLF; PIR; ARID4A; MED21; CAMTA1; WHSC1; HOXD10; BANP; THAP4; CCDC59; HEY2; EYA1; FOXJ2; BCLAF1; TEAD3; NR1H2; ING1; SMAD1; CBX3; DAXX; NRBF2; ZNF134; HOXC10; IKZF5; CARM1; KLF11; TAF5; TCF7L1; MNAT1; NFIL3; ZXDC; NFKB2; RAN; KAT7; CBX5; RREB1; SUMO1; RXRA; ATF4; NFIB; GATA1; BHLHE40; NR1D2; ZNF248; PRRX2; ARNTL; ZNF467; MAF; PMS1; RBBP7; UIMC1; SP100; ZNF443; ZNF468; ZNF331; ZNF211; WWTR1; NFRKB; ZNF23; BCL6; GRHL2; TGIF1; ZNF3; BBX; PPARD; BACH1; OVOL2; ZNF562; AGO2; MAFG; ZNF8; KDM2A; OSR2; NR2F2; ZNF239; GTF3A; ZNF654; SIN3B; TTF1; FOXC1; COPS2; NFIC; PURA; ZNF266; PSPC1; MED27; ZNF552; ING2; NPM1; ZBTB1; HLF; RYBP; CNBP; ZBTB11; USP16; SERTAD2; SCAND1; RORA; APEX1; HNRNPD; YBX1; SATB1; GATA2; NCOA4; ZNF44; SUV39H1; ZNF180; ABL1; ZNF32; MITF; ZNF787; HOXD11; KAT6A; RNF138; ARNTL2; HOXC6; BCL3; CREM; ZNF419; WIZ; BIRC2; BRD3; ESR1; ZNF580; KLF3; FOS; RBM39; SPEN; XBP1; TCF7L2; HOXB7; CRYM; KMT5A; ZNF544; HDGF; E2F2; NFYC; HMGA2; ZNF148; NFATC3; HOXD3; HOXA11; TLE1; ZNF512B; ASH2L; MAGED1; ZBTB38; DBP; ZNF586; PAXBP1; SOX10; MYCL; RBBP8; MYCBP; SAP18; ZNF587; TRIM28; MECOM; MAFB; CREB1; IL16; TBX3; CBX6; NKX2-2; NFAT5; ZNF423; ZNF131; IRF4; GATA3; SIX1; TCF4; NUP62; HHEX; MSX1; NKX3-1; TCFL5; ERBB4; KAT6B; EGR2; KLF4; BASP1