Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76162	Canertinib	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	322	HDAC6; SSBP2; ADRB2; TSC22D4; MEN1; SKI; HABP4; ZNF226; LPIN2; NFATC4; E2F2; TRRAP; ZNF671; FOXJ1; ZNF175; ZKSCAN7; ZNF711; WHSC1L1; NR3C2; TP63; HCFC2; ELF3; ZNF510; ZNF639; ZNF536; RELA; NFATC1; CREB3L1; CARF; BCL6; PITX2; CIR1; ZFPM2; ZNF141; THAP10; TDRD3; AFF2; EGR2; NCOA2; HOXA3; PKNOX2; KLF5; ZNF506; ATF3; SERTAD2; ZNF432; EZH1; MYNN; PATZ1; RSF1; SAP18; LHX1; CALCOCO1; KDM5D; NR4A1; ZNF224; RCOR1; MAGED1; HMGN3; ZNF205; ZNF225; NEUROD2; ZNF180; ZNF235; NRBF2; SPDEF; TAF6L; ERBB2; SP2; ZNF112; RARB; ZNF227; ZNF682; ZBTB20; ARNTL; ZNF770; SIM2; BRDT; MYF5; AATF; FOXE1; ZNF248; HOXA1; SOX5; TCF15; ZBTB3; ZNF202; ZNF184; HNRNPD; DDX54; CDK8; ZNF623; GTF2I; ZNF415; MBD2; PRDM2; ANKRD1; LITAF; PBRM1; ONECUT2; ACTL6B; HLF; TFDP2; BHLHE41; ZMYM2; THRAP3; ZBTB16; YEATS4; STAT5B; EHMT2; ZNF10; ZIC1; MYOG; ZSCAN18; CITED1; EGR1; PSPC1; TBX21; IFNB1; ZNF606; CUX2; ZNF493; GATAD2A; ZNF45; GATA2; SOX10; FOSL2; HIVEP2; PLAG1; BANP; NKX2-1; ZNF354A; ZNF8; NFIX; ZNF14; BHLHE40; TGIF1; CD3D; SIRT7; HMGA2; ZKSCAN5; HOXC4; MYT1; ZNF701; TSC22D1; TSHZ2; ARRB1; MAK; RNF111; NR2F1; OVOL2; ERBB4; TCF7L2; SMAD2; ETV1; DPF2; KLF9; IKZF1; CREB3; TRIP11; PBXIP1; ELF5; ZNF652; ZNF768; ZNF222; NKX3-1; NEUROG1; ZBED1; TEAD3; PHOX2B; EBF2; FOXI1; TRIM24; ARID5B; MEIS1; TOX4; ETS2; ZNF350; NRL; ZEB2; HNF1B; STAT2; ZNF131; BNC1; NPAT; NHLH2; TCFL5; ETV7; PRPF6; SAP130; MTA1; HES1; BCOR; ZBTB44; ZSCAN9; EN2; NFX1; MYT1L; HIVEP1; ZNF133; PEX14; FOXF2; NR4A3; YAF2; WHSC1; AEBP1; EHF; CBFA2T3; ERCC2; ARNTL2; HOXA10; ZSCAN16; CRTC1; ENO1; ZNF93; TSC22D3; NR1H3; MAF; TRIM32; TEAD1; YBX1; NR4A2; PAWR; MED4; DEAF1; PPARD; ZNF34; DMTF1; HOXD3; HMGA1; RBL2; GFI1; TERF1; AR; ZNF529; KDM2A; ZNF423; NFKB2; ZNF500; PIAS3; ZNF813; ZNF331; CEBPD; HOXB13; PPARG; ZNF239; NKRF; HOXD1; SOX11; L3MBTL1; ZNF629; NR1H2; TAL1; ATF5; ZNF107; KLF2; CREG1; FOSB; SSX1; TAF1; RING1; ZNF264; TDP2; TAF7; SALL2; GATA6; MYCN; YAP1; GABPB1; SOX9; MXD4; IRF4; FOS; BRCA1; NR1D2; ZNF574; TCEA1; SMAD6; PAX6; THAP11; E2F3; MDM2; ELF1; ZNF273; WT1; RBBP4; NUP62; SLC2A4RG; GTF2IRD1; SPEN; GRHL2; TAF9B; CREBL2; EGR3; FOXF1; IRX5; ZFHX4; CREB1; CUX1; STAT3; RUVBL2; DAXX; CHD3; HMBOX1; ZNF43; KLF4; HTATIP2; SNAI2; AGO2; NFATC3; PAX8; TRIM29; ASH2L; POU2AF1; CEBPA; NCOA1; AHR; ACTL6A; TCF7; ZEB1; TCF4; TXNIP
Down-regulation	347	HDAC2; CCNA2; SP3; TEAD4; BTG1; INSM1; GTF2A2; ITGB3BP; NR0B2; RFC1; RBPJ; BRD2; MYBL2; MED23; MYBBP1A; SOX13; INSR; ZNF516; CCNC; HCFC1; CARHSP1; ZNF263; ESR1; ARID1A; HSF2; GLI3; ATF2; HMG20B; USP22; RYBP; SP110; PHIP; RUVBL1; TAF9; ZNF12; ZNF215; CCDC59; SREBF1; ADNP; FOXM1; RNF138; BCLAF1; NFYA; TADA3; TFCP2L1; ZFP36L2; HDAC5; ZNF668; PPARA; TBPL1; ZNF408; PBX1; ATN1; HMGB2; WWTR1; THAP7; RBM39; MTF1; CDK2; SMARCA5; SCAND1; PIAS1; KLF1; HOXB5; HDAC9; SUPT3H; CHD9; FUBP1; SNIP1; PAX5; KLF6; ZBTB1; ZXDC; TFEB; TAF5L; SAP30; SMARCB1; NCOA3; PMS1; GON4L; RERE; IKZF5; ENY2; ZNF32; UTF1; CARM1; TGIF2; ZNF302; SUPT6H; AES; BAZ2B; CSDE1; SNAPC4; ZNF83; GMEB1; NANOG; MNAT1; SMARCA4; ZMYND8; FOXN2; MED13; RAD21; PHF2; SF1; KLF10; ZNF467; HNF1A; CHD8; ZNF292; TAF10; SMARCD2; ZMIZ1; POU5F1B; PMF1; PAXBP1; CHAF1B; TCF12; CCNE1; ABL1; ERG; HOXD10; NR2F2; MYCBP; FLNA; WWP1; NR0B1; TAF1C; C1D; SIX2; ECD; PFDN5; PARP1; ALX1; ZNF274; PAX9; NFE2L1; GTF2A1; SIM1; RXRG; EED; CBX8; MED24; HBP1; NFIC; PSIP1; IKBKAP; ZKSCAN1; COPS2; MLXIP; EZH2; ZNF444; ELK3; CALR; ING1; MZF1; DLX2; REST; KAT2A; USP16; ZNF148; BRD4; TCF21; ZNF573; ID1; SAFB2; LMCD1; VEZF1; CBX6; ILF2; DDIT3; UBP1; TP53; SPI1; DACH1; RARA; PCGF1; HOXB7; CEBPG; PREB; ZNF528; HOXB6; ZNF654; CEBPZ; TRAK1; JARID2; TAF12; MMS19; ZNF232; C1QBP; TRIM28; KLF11; HMG20A; ZNF692; ZNF672; TRIM33; TCF3; KLF7; ZNF146; MEF2D; TOPORS; MSX1; TTF2; HOXD11; NELFB; ZBTB11; HDAC1; POU4F1; HLTF; SP140; BAZ2A; EWSR1; GABPA; KMT2B; ZNF281; ARID3B; SMAD4; ZNF3; ZNF24; MED14; ZNF552; MLX; MED15; IRF7; MED17; ZNF124; PA2G4; RBBP7; LOXL2; UBTF; PTTG1; NR1H4; IRF8; CDK9; USF2; MED16; RNF10; NCOA4; ZNF721; SMAD1; KDM5B; CHD7; SATB2; STAT6; RAN; ZNF665; MTF2; PPRC1; TGFB1; BAZ1B; EMX2; PIAS4; CENPF; E2F6; TULP3; TBL1XR1; MNT; ETS1; PSMD9; MTDH; BRD8; ZNF44; ELF2; LHX6; ESRRA; CLOCK; IRF2; PEG3; HDAC3; SFPQ; SREBF2; TCERG1; COPS5; FOXK2; KAT6B; SIX3; IRF6; HOXA11; TBP; SMAD3; ID2; NFYC; PLAGL2; ARID3A; ZNF468; HDAC4; TLE1; ZNF91; HIC2; SUB1; TSC22D2; ZNF551; CRK; SOX15; ZNF593; UBE2B; TCF7L1; RHOA; TRPS1; RREB1; HSF1; RBFOX2; TFAP2C; BTAF1; CHD1; HIPK1; PITX1; HIPK3; VPS72; OSR2; STAT1; CITED2; ZBTB18; NRIP1; SIAH2; BBX; FOXO3; TRIP6; TFCP2; BIRC2; NFKB1; ID3; TBL1X; SATB1; TAF1D; MYB; RB1; PNRC1; FOXJ3; PDLIM1; FOXO1; NKX2-2; EDF1; CBFB; SOX2; JUNB; PCGF2; ZNF266; ING2; ZNF160; HMGB3; ASCL1; ZNF586; SUV39H1; ARID4B; BASP1; GATA3; MEIS2