Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76161	Canertinib	GSE92742	MCF10A	Human	24h	2uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	174	SMARCA5; SMARCD3; MXD1; SIRT2; TSC22D3; RSF1; BACH2; TCF3; FOXN3; SUPT5H; FOXL2; ZNF205; SOX17; TSC22D4; KDM5C; PBX2; FOSL2; TRIM16; HIVEP1; RELA; CRYM; SMARCA2; TFAP4; TCF4; CDK2; MEF2D; HMX1; LPIN2; THRA; SOX2; NR4A3; EVX1; UBE2L3; DACH1; CIR1; RBFOX2; ELK4; NR0B2; ARID5B; WHSC1L1; NR3C1; STAT2; POLR3C; ZKSCAN1; MYRF; SMAD2; GTF2F1; ZNF74; COPS2; TDP2; TWIST1; YEATS2; NFE2L3; ZNF394; BTG1; TAF7; NANOG; ZEB2; ELF4; NAB2; BARX1; MEIS2; BNC2; CUX2; MAZ; NPAS2; TLE4; BCL11A; MKL2; FLI1; TERF1; SF1; POU5F1B; CREBL2; PBXIP1; THAP11; HMGA1; HOXB3; SPDEF; NR2F1; SPIB; SND1; SMARCC2; FOXA1; TOX4; PLAG1; NR4A1; HLX; FOXO1; RING1; SSRP1; SSX1; ARID4B; LITAF; NCOA2; HDAC9; MED13; NCOR2; ARID1A; SREBF1; RB1; ZNF117; BRD7; SOX12; JUNB; MNT; ZEB1; BRF2; WT1; CERS6; IRF2; TCEA2; MED24; ISL1; CREB3L1; HEY1; CBX5; SOX4; NFKBIA; ETS1; ASH2L; POU4F1; BAZ2A; MYCL; NR4A2; CBX4; HOXA5; CREM; MXD4; AES; NR3C2; PLAGL1; MECOM; RBBP8; SMARCA1; KLF2; STAT3; BCL10; TRIM29; PNRC1; SIX2; FOXO3; TSC22D2; FOXG1; FOSB; HMGB3; PFDN5; PCGF2; CCNH; FOS; ATF3; SMAD3; TAL1; ZNF274; MTF2; RFXANK; SNAI2; GATA6; ZBTB38; TFCP2; PBX3; RUNX1; ATF5; KLF5; GATA3; ERBB4; IRF9; KAT6B; EMX2; SMAD7; MYB; MEIS1; ID4; HIC2
Down-regulation	185	GTF3A; GTF2A2; CENPF; DNMT3B; CCNA2; VGLL4; SERTAD2; HDAC2; WWTR1; PMS1; FOXM1; GCFC2; TRIM32; NEUROD1; RBBP7; CNBP; ZNF16; NFIB; ZNF250; ZNF211; PTTG1; FUBP1; EZH2; ATF4; PAX6; ELF5; NR2C1; CTBP1; ZMIZ1; BLM; HMGB1; EN2; RREB1; KDM5D; HDAC1; HLTF; PSPC1; HOXA1; RFC1; WHSC1; TAF1A; ZNF7; HSF2; CRY1; ZXDC; ITGB3BP; CDK8; ARNTL2; ZNF83; AHR; ZNF329; BHLHE41; RXRA; PHF20; DR1; CCNC; PTRF; NCOA6; CD3D; BATF3; ZSCAN32; ZNF419; AATF; TAF9B; TAF5; BCLAF1; CAMTA1; CEBPZ; EN1; SCAND1; ZBTB20; TAF4; ENO1; RBL1; HMGA2; CARHSP1; TLE2; KAT2B; SOX10; ZNF34; NFATC3; CCDC59; TBL1X; FLNA; HOXC10; JARID2; ZNF8; ABL1; BANP; LMCD1; RNF6; PSMC3IP; PSIP1; PAXBP1; ASXL1; HMGN3; TOB1; CHD7; HMGB2; CEBPG; SP110; ZNF217; ZNF304; BRPF1; ELK3; CITED2; RBPMS; PPARG; YEATS4; MSX1; DDIT3; TBL1XR1; RNF4; PCGF1; ZNF692; BTAF1; ZNF180; TFDP1; NAB1; FOSL1; SUV39H1; PIAS1; TFDP2; NKX2-1; HNRNPD; ZNF148; FOXC1; IRF5; RBM39; HLF; SOX9; ZBTB11; NR1H3; HOXB7; DEK; MYCN; ST18; KLF10; HDGF; TBX2; HOXC6; RNF10; SATB1; ETV5; BRCA1; SPEN; DMTF1; RUNX3; TCEA1; TRIM28; OSR2; TCFL5; MAFB; IRX5; C1D; EDF1; SLC2A4RG; ZNF580; BIRC2; TGFB1; NR2F2; CCNE1; MYCBP; ZNF443; ZMYND8; SALL1; TCF7; ZNF586; ZNF266; NUP62; MXI1; ZBED2; CBX7; PDLIM1; ZNF131; CREB1; EGR2; STAT1; CBX6; HOXA10; CREB3L2; MAF; TFAP2C; ID1; BASP1