Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76160	Canertinib	GSE92742	MCF10A	Human	24h	10uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	171	E2F2; LEF1; RSF1; CSDC2; BTG1; SSBP2; HOXB1; ZBTB16; ZNF675; ZNF154; SOX17; HOXB13; HAND1; TSC22D3; PBXIP1; ZNF215; TTF2; ZSCAN18; TP73; SMARCC2; SCRT1; ZNF257; TBX5; BACH2; GATA6; ZNF688; FOXI1; GTF2F1; ZNF91; CALCOCO1; ZKSCAN1; ZHX2; SOX13; DYRK1B; SIRT7; MAML1; NAB2; ZNF195; PGR; ZNF141; CDIP1; SOX18; ZNF93; POU4F1; ZNF711; ID3; EHF; ZNF268; TRIM29; BRIP1; CHD9; EHMT2; GTF2I; BAZ2A; ELK4; ZNF85; ZNF117; DDIT3; TRIP11; PBX3; CNOT6; TCF21; JUP; PAX5; MEIS2; NFE2L3; ZNF667; NEUROG1; WNT4; PBX2; SUPT6H; APBB1; TCF3; MZF1; TAF7; SPIB; ZFP69B; CREG1; ZNF354A; POU2AF1; SIRT2; MED12; ZFP36L2; FLI1; TOX; DACH1; CLOCK; ZNF516; E2F5; HBP1; AEBP1; FOXL2; INSM1; ZNF430; FOXN3; ZNF394; RFXANK; PBX1; OSR2; MTA1; CREBL2; BAZ2B; WT1; MED13; MNT; TLE4; KLF5; NPAS2; SREBF1; STAT4; NHLH2; NFKBIA; ETS1; TRAK1; JUND; CDK9; ZBED1; ZNF423; HES1; RFX5; RB1; SOX2; TP63; IFI16; PRKDC; HOXD1; TFAP2C; MYBL1; ID1; HOXA11; CREB1; TAF9B; NR4A2; CTBP2; HOXA5; ZNF586; ZNF415; PFDN5; ERBB2; SPDEF; HOXD3; SSX1; ZNF43; MED1; JUNB; ZEB1; BHLHE41; TAL1; MECP2; TLE1; CUX1; NR1H2; VPS72; ZNF304; ZNF107; PITX1; BCL11A; MYRF; FLNA; SOX9; VDR; ARID4B; CHD7; ZNF331; RUNX1; CRK; RBBP8; SUZ12; TRIM22; TRPS1; TBX3
Down-regulation	213	CCNA2; SP3; ENO1; AHR; FOXM1; DNMT3B; HLTF; GTF2A2; CHAF1B; DR1; CBX3; HDAC2; CDYL; BHLHE40; CENPF; NKRF; EZH2; BACH1; GCFC2; HSBP1; NFIB; BATF3; HMGXB4; KAT7; SAP30; UBP1; KDM5D; DEK; TRIM32; NR1D2; ORC2; MYCBP; EYA1; HSF2; TBPL1; CRY1; ZNF248; BCLAF1; ZNF217; ZNF239; POLR2A; CASZ1; THAP1; PTTG1; ARNTL; ETV5; URI1; CALR; ELF2; ZNF32; DAXX; NKX2-1; PIAS1; TCF7L2; RNF111; FHL2; CEBPZ; SNIP1; EGR1; CCNE1; HOXC6; HDAC3; DRAP1; NANOG; ZNF337; HLF; ADNP2; THAP7; KLF10; YBX1; PPP1R13L; ZNF23; ZNF652; SERTAD2; NCOA4; GTF3A; BRD3; USP16; BANP; LIMD1; BAZ1B; BMI1; HOXB7; BLM; ING1; FUBP1; RNF138; DNAJC2; PSPC1; LMCD1; SUB1; TFCP2L1; CDC5L; NFATC3; MAFG; RBM14; PMS1; ADNP; HOXC10; ATF5; GRHL2; MYNN; XBP1; CNBP; C1D; CARHSP1; CREB3L2; ZNF384; MAZ; SPEN; ELF3; PEX2; SAP18; ETV4; FOSL1; CTNNB1; HMGB2; SMAD4; CARM1; SETD2; BIRC2; TOB1; ETS2; MGA; SUV39H1; PPARG; TAF1D; NFAT5; TSC22D2; ZNF22; NEDD8; ZNF175; CXXC1; IKBKAP; HMGB1; CHD1; HEY1; NFKB2; MED15; SOX4; KLF4; HOXB2; CENPB; MYCL; BRCA1; E2F3; ZNF329; PA2G4; KLF7; MEOX2; ARNTL2; ING3; MAFB; ZBTB11; HOXC4; EP300; NPM1; PDLIM1; CBFB; SALL2; ZNF721; ELF1; SATB1; HNRNPD; TCFL5; ZMIZ1; JARID2; TRIM24; ELK3; CRYM; CITED2; AFF1; PAXBP1; COPS2; NR4A1; ATF3; IRF8; SFPQ; HMGA2; CCNC; TGIF1; ZNF267; TCF7; ZNF124; EGR3; SOX10; HMBOX1; ELF5; ZNF131; SMAD3; SMARCA1; NR2F2; AGO2; HIC2; ING2; HHEX; TRIM28; TSC22D1; ZBED2; SIX1; CBX6; NUP62; KAT6B; RBPMS; MYB; HOXA10; ERBB4; IKZF1; DMTF1; EGR2; GATA2; GATA3; BASP1