Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID76150	Olaparib	GSE92742	MCF10A	Human	24h	0.4uM	EID0437

Response Information :

Types	Number	Response transcription factors
Up-regulation	172	CHD9; CREM; GTF2I; ETV6; ENO1; NSD1; SFMBT1; NEUROD1; DACH1; MLLT10; PEX14; INSM1; ID2; MDM4; TTF2; SMAD6; ERG; ACTL6B; ZNF235; TAF4B; ATF6B; RBL2; FOXN2; BRD4; RFX7; MAP3K10; MAML1; CRYM; SMAD2; LMCD1; TP73; ZNF10; MED25; KLF15; VGLL4; ZNF195; HNF1A; ARL2BP; ZNF215; BRD2; ZBTB25; UBP1; ZNF124; TCF12; CDX1; BRCA2; ZFP64; HTATIP2; PBX3; EHMT1; HOXA10; FOXJ3; REL; NR0B2; TAF9; TFDP2; YEATS4; HMBOX1; EPAS1; NR1I2; NR4A3; ZNF444; HOXA5; NLK; GATA1; NEUROG1; TDP2; ARID1A; TEAD4; LEF1; NKX2-1; RNF14; GABPA; HOXA7; EHMT2; BTG1; ZNF302; BCL6; MZF1; NFE2L3; ZNF43; POU2F1; MNT; ZNF85; SMAD4; SPDEF; ERBB2; SP140L; CBFB; NHLH2; CDK8; ZNF232; MED27; RSF1; RNF138; FOXJ1; ZFP36L2; BRCA1; HMG20A; PKNOX1; ID1; CUX1; RFX5; CREBL2; ZNF33B; TOX3; ID3; CTBP2; SP100; RAD21; PRMT2; KLF10; CBFA2T3; HMGA1; STAT1; SMAD7; PDLIM1; PAWR; SOX4; ZNF551; ETV5; CCNT1; STAT4; REPIN1; TRIM24; FOXA1; TCF7; MTF2; PURA; IRX5; SERTAD2; PROX1; FOXA2; ABL1; PCGF1; ETS1; ASCL1; ATF1; MED13; ZNF131; RBBP8; ZNF544; SNAI2; ZEB1; TRIM22; DAXX; ZNF586; IRF7; CLOCK; RB1; NR4A2; NFKB1; SREBF1; KLF5; TCFL5; ZNF423; BCL3; RUNX1; FOXC1; TRIM28; BIRC2; KLF13; VDR; BCL11A; IRF8; GATA6; SOX9; CRK; CREB1; SATB1; FOS; IKZF1
Down-regulation	202	SALL2; MTF1; PBX1; PITX1; RCOR1; HDAC5; SMARCD3; PCGF3; CALCOCO1; CCNA2; HMGB1; MED15; TRRAP; PEG3; NANOG; CERS4; CEBPE; TFE3; HEY2; TSHZ2; NFIB; TRIM16; NKX2-2; CHD8; BTAF1; SIAH2; ZNF133; RNF141; TCEA1; UBE3A; PKNOX2; HSF2; ZFP36L1; CIR1; PBXIP1; HLF; TEAD3; CENPB; KDM5D; SCAND1; NEDD8; ZNF337; CITED2; FHL2; HMGXB4; ZNF410; NR2F2; REXO4; PSMC3; RLF; L3MBTL1; ADNP2; SNIP1; ZNF32; ZMYND11; HIVEP2; ZNF426; HIPK2; SPIB; PTRF; RBM39; TLE4; FOXK2; GMEB2; SOX15; WT1; YBX3; IKBKAP; PLAGL1; SUZ12; NR2F1; NR1H2; TSG101; WWP1; COPS5; ZNF611; SUB1; WWC1; KDM5B; NELFB; TSC22D3; CTNNB1; ZNF467; TOX4; VEZF1; MEOX2; BRD3; RBBP5; MLXIP; TLE1; ZNF274; EZH1; NR1H3; MAF; KAT2B; MED12; ZMIZ1; HOXD11; ZNF83; MXI1; MAFF; ZNF266; SAP18; GTF3A; ESR1; MEIS1; ARID3B; SPEN; BHLHE41; MITF; NCOA2; RNF10; ZNF516; EZH2; JARID2; NCOA4; IRF1; ST18; OLIG2; THAP11; MEOX1; TBPL1; GATAD2A; CD3D; ZNF512B; CCNE1; MED24; HOXB2; ZFHX3; BAZ1B; RBPMS; RORA; ISL1; SIX1; HDAC3; USF2; ZNF652; HIRA; TRPS1; OSR2; EMX2; PSIP1; USP16; MED6; HIC2; KAT6B; TOX; ZNF281; MAFB; PIAS3; ZBTB20; MYCN; TFAP2C; GTF2IRD1; PLAGL2; SRF; HOXC6; RREB1; HNRNPD; ARID4B; FLNA; HHEX; BACH2; HMGB3; CIZ1; ZMYM2; ZFHX4; HOXC4; JUP; KAT2A; GRHL2; MTA1; TCF4; TP53; PRKDC; PHF20; GABPB1; SHOX2; CBX7; ID4; FOSL1; POU2AF1; UBE2B; CNOT2; PCGF2; SMAD3; MYCL; EGR3; YWHAB; ZFPM2; EDF1; CBX6; TBX3; TRIM29; KLF4; TCEB2; TGFB1; EGR2; DMTF1; BASP1; NUP62; MEIS2